公开(公告)号：NO20012734A

公开(公告)日：2001-06-01

申请号：NO20012734

申请日：2001-06-01

Applicant: BASF AG

Inventor： BERTLEFF WERNER ,  BROECKEL ULRICH ,  FRICKE HELMUT ,  HARZ HANS-PETER ,  WITT REINER

IPC: A61K9/16 ,  A61K20060101 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/62 ,  A61K9/64 ,  B01J2/00 ,  B01J2/10 ,  B01J2/28

CPC classification number: B01J2/006

公开(公告)号：DE19856149C1

公开(公告)日：2000-06-15

申请号：DE19856149

申请日：1998-12-04

Applicant: BASF AG

Inventor： BERTLEFF WERNER ,  BROECKEL ULRICH ,  FRICKE HELMUT ,  HARZ HANS-PETER ,  WITT REINER

IPC: A61K9/16 ,  A61K20060101 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/62 ,  A61K9/64 ,  B01J2/00 ,  B01J2/10 ,  B01J2/28

Abstract: The invention relates to a method for producing agglomerates comprising a core-shell structure in which: i) primary agglomerates are prepared that contain a first particle-shaped solid; ii) a second particle-shaped solid is agglomerated in the presence of the primary agglomerates while adding a binding liquid in order to obtain agglomerates of the second stage, and optionally; iii) an nth (n>/=3) solid is agglomerated in the presence of the agglomerates of the (n-1)th stage while adding a binding liquid in order to obtain agglomerates of the nth stage.

公开(公告)号：NO972912L

公开(公告)日：1997-08-19

申请号：NO972912

申请日：1997-06-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16 ,  A61J3/06

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：ZA9510958B

公开(公告)日：1997-06-23

申请号：ZA9510958

申请日：1995-12-19

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16 ,  A61J

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：AU4434196A

公开(公告)日：1996-07-19

申请号：AU4434196

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JORG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：DK1135108T3

公开(公告)日：2004-07-12

申请号：DK99962207

申请日：1999-12-03

Applicant: BASF AG

Inventor： BERTLEFF WERNER ,  BROECKEL ULRICH ,  FRICKE HELMUT ,  HARZ HANS-PETER ,  WITT REINER

IPC: A61K9/16 ,  A61K20060101 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/62 ,  A61K9/64 ,  B01J2/00 ,  B01J2/10 ,  B01J2/28

Abstract: A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated in the presence of the initial agglomerates with the addition of a binder liquid to give second stage agglomerates and, where appropriate, iii) an nth (n>=3) solid is agglomerated in the presence of the (n-1)th stage agglomerates with the addition of a binder liquid to give nth stage agglomerates.

公开(公告)号：BR9915952A

公开(公告)日：2001-08-21

申请号：BR9915952

申请日：1999-12-03

Applicant: BASF AG

Inventor： BERTLEFF WERNER ,  CKEL ULRICH BR ,  FRICKE HELMUT ,  HARZ HANS-PETER ,  WITT REINER

IPC: A61K9/16 ,  A61K20060101 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/62 ,  A61K9/64 ,  B01J2/00 ,  B01J2/10 ,  B01J2/28

Abstract: A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated in the presence of the initial agglomerates with the addition of a binder liquid to give second stage agglomerates and, where appropriate, iii) an nth (n>=3) solid is agglomerated in the presence of the (n-1)th stage agglomerates with the addition of a binder liquid to give nth stage agglomerates.

公开(公告)号：AU699971B2

公开(公告)日：1998-12-17

申请号：AU4434196

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JORG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：AT171613T

公开(公告)日：1998-10-15

申请号：AT95943202

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：ES2217857T3

公开(公告)日：2004-11-01

申请号：ES99962207

申请日：1999-12-03

Applicant: BASF AG

Inventor： BERTLEFF WERNER ,  BROCKEL ULRICH ,  FRICKE HELMUT ,  HARZ HANS-PETER ,  WITT REINER

IPC: A61K9/16 ,  A61K20060101 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/62 ,  A61K9/64 ,  B01J2/00 ,  B01J2/10 ,  B01J2/28

Abstract: A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated in the presence of the initial agglomerates with the addition of a binder liquid to give second stage agglomerates and, where appropriate, iii) an nth (n>=3) solid is agglomerated in the presence of the (n-1)th stage agglomerates with the addition of a binder liquid to give nth stage agglomerates.