公开(公告)号：WO2006002999A3

公开(公告)日：2006-09-08

申请号：PCT/EP2005007289

申请日：2005-07-06

Applicant: BASF AG ,  HETTCHE FRANK ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  PACIELLO ROCCO

Inventor： HETTCHE FRANK ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  PACIELLO ROCCO

IPC: C07C67/303 ,  C07C69/34

CPC classification number: C07C67/303 ,  C07B2200/07 ,  C07C69/34

Abstract: The invention relates to a method for producing optically active alkyl succinic acid monoalkyl esters of formula (I), wherein D and E independently represent H, C 1 -C 10 alkyl, RC 1 -C 10 alkyl, aryl, or alkylaryl.

Abstract translation: 本发明涉及一种制备式的旋光活性Alkylbernsteinsäuremonoalkylestern（I），其中D和E彼此独立地H，C _{1 -C 10 烷基，RC 的制备 1 -C 10 - 烷基，芳基，或烷芳基。}

公开(公告)号：DE102005044518A1

公开(公告)日：2007-03-22

申请号：DE102005044518

申请日：2005-09-16

Applicant: BASF AG

Inventor： FRIEDRICH MARKO ,  EBEL KLAUS ,  ZAHM CHRISTIAN ,  GOETZ NORBERT ,  KRAUSE WOLFGANG

IPC: C07C35/12 ,  A23L27/20 ,  B01J31/22 ,  C07C29/56 ,  C07C35/08

Abstract: Diarylphenoxy-aluminum compound (A), obtained by a reaction of bis(diarylphenol) ligand (I) with aluminum compound (II) and/or aluminum compound (III), is new. Diarylphenoxy-aluminum compound, obtained by a reaction of bis(diarylphenol) ligand of formula (I) with aluminum compound (II) of formula ((R 14>) 3-pAlH p) and/or aluminum compound (III) of formula (MAlH 4), is new. T : 1-6C-alkyl, 1-6C-perfluoroalkyl, 1-6C-alkoxy, 7-12C-aralkyl, halo, optionally substituted 6-10C-aryl or NO 2; Ar 1>-Ar 4>6-15C aryl or 2-15C heteroaryl (optionally substituted by 1-7 substitutions of T, SiR 5>aR 6>aR 7>a, NR 8>aR 9>a or SR 1>0a); either R 1>-R 4>H, T, SiR 5>bR 6>bR 7>b, NR 8>bR 9>b or SR 1>0b; or A+R 1>-R4 : aromatic or non-aromatic cycle; D : O, S, NR 11>, C(O), S(O) and/or S(O) 2; A : 1-25C-hydrocarbon, heteroatom of D, T, 1-10C-acyloxy, SiR 5>cR 6>cR 7>c, 2-10C-heteroaryl, NR 8>cR 9>c, SR 1>0c, 1-12-acyl, 1-10C-carboxyl, 6-15C-aryl or 2-15C-hereroaryl optionally substituted by 1-5 substitutions of T, SiR 5>dR 6>dR 7>d, NR 8>dR 9>d, SR 10>d, heteroatom of D, P(R 11>), (R 11>)P(O) or Si(R 12>R 13>); R 5>a-R 5>d, R 6>a-R 6>d, R 7>a-R 7>d, R 10>a-R 10>d, R 11>-R 13>, R 11>a : 1-6C-alkyl, 7-12C-aralkyl and/or optionally substituted 6-10C-aryl; either R 8>a-R 8>d, R 9>a-R 9>d : 1-6C-alkyl, 7-12C-aralkyl and/or optionally substituted 6-10C-aryl; or R 8>aR 9>a, R 8>bR 9>b, R 8>cR 9>c, R 8>dR 9>d : 2-8C cyclic hydrocarbon containing one or more hetero atoms of O, S or NR 11>a; Al : aluminum; R 14>1-5C-alkyl; p : 0-3; and M : Li, Na or K. Independent claims are included for: (1) a preparation of isopulegol (IV) comprising cyclization of citronellal (V) in the presence of (I) as a catalyst; and (2) a method for preparing menthol comprising preparing (IV) and subsequently hydrogenating the ethylenic double bonds in (IV). [Image].

公开(公告)号：DE102005023953A1

公开(公告)日：2006-11-23

申请号：DE102005023953

申请日：2005-05-20

Applicant: BASF AG

Inventor： GOETZ NORBERT ,  EBEL KLAUS ,  FRIEDRICH MARKO ,  KRAUSE WOLFGANG

IPC: C07C35/17 ,  A23L27/20 ,  B01J31/14 ,  C07C29/56 ,  C07C35/08

Abstract: A method for the production of isopulegol involves the cyclisation of citronellal in presence of a tris-(1,3-diaryl-2-naphthoxy)-aluminum compound as catalyst. A method for the production of isopulegol (formula I) involves the cyclisation of citronellal (formula II) in presence of a tris-(1,3-diaryl-2-naphthoxy)-aluminum catalyst of formula (III), in which R1>, R2>H, halogen and/or 1-4C alkyl (in the o-, m- and/or p- positions); R3>-R6>H, halogen or 1-4C alkyl. Independent claims are included for (1) aluminium compounds of formula (III) (2) a method for the production of 1,3-diaryl-2-naphthols of formula (VI) by reacting a benzaldehyde of formula (XI) with a diphenyl ketone of formula (XII) to give an unsaturated ketone of formula (XIII), then reacting (XIII) with bromine and cyclising the product by treatment with a carbonate. [Image] [Image] [Image].

公开(公告)号：DE102004063003A1

公开(公告)日：2006-07-13

申请号：DE102004063003

申请日：2004-12-22

Applicant: BASF AG

Inventor： FRIEDRICH MARKO ,  EBEL KLAUS ,  GOETZ NORBERT

IPC: C07C29/56 ,  C07C35/17

Abstract: The present invention relates to a process for the preparation of isopulegol of formula (I): comprising the cyclization of citronellal of formula (II): in the presence of a tris(aryloxy)aluminum catalyst, wherein the cyclization is carried out in the presence of I. at least one acid and/or II. at least one compound selected from the group comprising carboxylic anhydrides, aldehydes, ketones and vinyl ethers.

公开(公告)号：DE102004055731A1

公开(公告)日：2006-05-24

申请号：DE102004055731

申请日：2004-11-18

Applicant: BASF AG

Inventor： PINKOS ROLF ,  EBEL KLAUS ,  HAUNERT ANDREA ,  KOCH MICHAEL ,  FRIEDRICH MARKO ,  MAAS STEFFEN

IPC: C07C209/68 ,  C07B63/00 ,  C07C209/84 ,  C07C211/62 ,  C07C211/63 ,  C07D521/00

Abstract: Single-step preparation of quaternary ammonium hydroxide (I) comprises conversion of quaternary ammonium formates (IIa) or quaternary ammonium carbonates (IIb) into (I) in the presence of a solvent and a catalyst, which is at least a metal of the groups 8-12 of the periodic system of the elements. Independent claims are included for: (1) (I) obtained by the method; and (2) use of metal of the Group 8-12 of the periodic system of element for preparing (I).

公开(公告)号：DE102004032968A1

公开(公告)日：2006-02-09

申请号：DE102004032968

申请日：2004-07-07

Applicant: BASF AG

Inventor： HETTCHE FRANK ,  JAEKEL CHRISTOPH ,  FRIEDRICH MARKO ,  PACIELLO ROCCO

IPC: B01J31/24 ,  C07C67/303 ,  C07C69/40

Abstract: Preparation of optically active alkyl succinic acid monoalkyl esters (I) comprises enantioselective hydrogenation of ester compounds (II) in the presence of a catalyst, which carries a phospholane ligand (L). Preparation of optically active alkyl succinic acid monoalkyl esters of formula (I) comprises enantioselective hydrogenation of ester compound of formula (II) in the presence of a catalyst, which carries a phospholane ligand of formula (L). D, E : H or 1-10C alkyl; R : 1-10C alkyl, aryl or alkylaryl; R 2>1-6C alkyl, aryl or alkylaryl; R 1>H or R 2>; A : R 1>or heterocyclic compound of formula (b); and B1 : bridge member with 1-5C between two P-atom or Cp-Fe-Cp. [Image] [Image].

公开(公告)号：DE102005010329A1

公开(公告)日：2006-09-07

申请号：DE102005010329

申请日：2005-03-03

Applicant: BASF AG

Inventor： FRIEDRICH MARKO ,  EBEL KLAUS ,  GOETZ NORBERT ,  KRAUSE WOLFGANG

IPC: C07F5/06 ,  B01J31/12 ,  C07B37/10 ,  C07B53/00 ,  C07C29/143 ,  C07C29/17 ,  C07C35/12 ,  C07C35/17

Abstract: Diarylphenoxy-aluminum compound (A), obtained by a reaction of bis(diarylphenol) ligand (I) with aluminum compound (II) and/or aluminum compound (III), is new. Diarylphenoxy-aluminum compound, obtained by a reaction of bis(diarylphenol) ligand of formula (I) with aluminum compound (II) of formula ((R 1> 4>) 3 - pAlH p) and/or aluminum compound (III) of formula (MAlH 4), is new. T : 1-6C-alkyl, 1-6C-perfluoroalkyl, 1-6C-alkoxy, 7-12C-aralkyl, halo, optionally substituted 6-10C-aryl or NO 2; Ar 1>-Ar 4>6-15C aryl or 2-15C heteroaryl (optionally substituted by 1-7 substitutions of T SiR 5>aR 6>aR 7>a, NR 8>aR 9>a or SR 1>0a); either R 1>-R 4>H, T, SiR 5>bR 6>bR 7>b, NR 8>bR 9>b or SR 1>0b; or A+R 1>-R4 : aromatic or non-aromatic cycle; D : O, S, NR 1> 1>, C(O), S(O) and/or S(O) 2; A : 1-25C-hydrocarbon, heteroatom of D, T, 1-10C-acyloxy, SiR 5>cR 6>cR 7>c, 2-10C-heteroaryl, NR 8>cR 9>c, SR 1>0c, 1-12-acyl, 1-10C-carboxyl, 6-15C-aryl or 2-15C-hereroaryl optionally substituted by 1-5 substitutions of T, SiR 5>dR 6>dR 7>d, NR 8>dR 9>d, SR 1>0d, heteroatom of D, P(R 1> 1>), (R 1> 1>)P(O) or Si(R 1> 2>R 1> 3>); R 5>a-R 5>d, R 6>a-R 6>d, R 7>a-R 7>d, R 1> 0>a-R 1> 0>d, R 1> 1>-R 1> 3>, R 1> 1>a : 1-6C-alkyl, 7-12C-aralkyl and/or optionally substituted 6-10C-aryl; either R 8>a-R 8>d, R 9>a-R 9>d : 1-6C-alkyl, 7-12C-aralkyl and/or optionally substituted 6-10C-aryl; or R 8>aR 9>a, R 8>bR 9>b, R 8>cR 9>c, R 8>dR 9>d : 2-8C cyclic hydrocarbon containing one or more hetero atoms of O, S or NR 1> 1>a; Al : aluminum; R 1> 4>1-5C-alkyl; p : 0-3; and M : Li, Na or K. Independent claims are included for: (1) a method for preparation of isopulegol of the formula (IV) comprising cyclization of citronellal compound of formula (V) in the presence of (I) as a catalyst; and (2) a method for preparing menthol comprising preparing (IV) and hydrogenating the ethylenic double bonds in the (IV).

公开(公告)号：DE10321627A1

公开(公告)日：2004-12-02

申请号：DE10321627

申请日：2003-05-13

Applicant: BASF AG

Inventor： GOETZ NORBERT ,  EBEL KLAUS ,  FRIEDRICH MARKO ,  MUELLER ULRICH

IPC: C07C29/56 ,  C07C29/00 ,  C07C35/17

公开(公告)号：DE10318043A1

公开(公告)日：2004-11-04

申请号：DE10318043

申请日：2003-04-17

Applicant: BASF AG

Inventor： FRIEDRICH MARKO ,  EBEL KLAUS ,  GOETZ NORBERT ,  MUELLER ULRICH

IPC: C07C29/56 ,  C07C35/08 ,  B01J21/12