公开(公告)号：RU2153504C2

公开(公告)日：2000-07-27

申请号：RU96123123

申请日：1995-04-26

Applicant: BASF AG

Inventor： VIL GEL M AMBERG ,  KHARAL D BERNARD ,  EHRNST BUSHMANN ,  ANDREAS KHAUPT ,  LOTAR JANICHKE ,  BERND JANSSEN ,  UL RIKH KARL ,  ANDREAS KLING ,  SHTEFAN MJULLER ,  BERND DEH POTTSOLLI ,  KURT RITTER ,  MARKO TIES ,  TOMAS TSIRKE

IPC: A61K38/08 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  A61K38/00 ,  C07K7/06 ,  C07K14/52

Abstract: medicine. SUBSTANCE: described is pentapeptide hydrochloride of formula I: Me2Val-Val-MeVai-Pro-Pro-NHBzl.HCl (I) wherein Me is methyl and Bzl is benzyl. Compound has antitumor activity. Also described are methods of preparation thereof. EFFECT: improved properties of the title compound. 6 cl, 2 ex