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1.发明专利
公开(公告)号：ZA90963B
公开(公告)日：1991-10-30
申请号：ZA90963
申请日：1990-02-09
Applicant: BASF AG
Inventor： JANSSEN BERND , BERND JANSSEN , WUEST HANS-HEINER , HANS-HEINER WUEST
IPC: A61K31/085 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/67 , A61K31/10 , A61K31/135 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/235 , A61K31/255 , A61K31/66 , A61P17/00 , A61P29/00 , A61P35/00 , A61P39/02 , A61Q19/00 , C07C39/17 , C07C43/20 , C07C43/205 , C07C43/21 , C07C43/23 , C07C45/44 , C07C47/575 , C07C49/643 , C07C59/68 , C07C59/70 , C07C63/44 , C07C65/21 , C07C65/24 , C07C65/26 , C07C69/035 , C07C69/76 , C07C69/773 , C07C69/92 , C07C69/94 , C07C205/34 , C07C205/37 , C07C211/60 , C07C215/76 , C07C217/48 , C07C217/58 , C07C217/76 , C07C217/84 , C07C217/86 , C07C219/34 , C07C223/02 , C07C223/06 , C07C225/16 , C07C225/22 , C07C229/36 , C07C229/38 , C07C229/60 , C07C233/18 , C07C233/25 , C07C233/43 , C07C233/44 , C07C233/47 , C07C233/55 , C07C233/75 , C07C233/80 , C07C235/42 , C07C237/30 , C07C239/02 , C07C239/08 , C07C255/51 , C07C255/54 , C07C259/10 , C07C309/42 , C07C309/46 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/16 , C07C323/19 , C07C323/20 , C07C323/32 , C07C323/34 , C07C323/36 , C07C323/40 , C07C323/41 , C07C323/56 , C07C323/62 , C07C327/22 , C07C327/30 , C07D257/04 , C07F9/38 , C07F9/40 , C07C , A61K
Abstract: Diphenylheteroalkyl derivatives of the formula I in which A and R -R have the meaning indicated in the description, and their preparation are described. The substances are suitable for controlling diseases and as cosmetic agents.
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2.发明专利
公开(公告)号：ZA9000963B
公开(公告)日：1991-10-30
申请号：ZA9000963
申请日：1990-02-09
Applicant: BASF AG
Inventor： JANSSEN BERND , BERND JANSSEN , WUEST HANS-HEINER , HANS-HEINER WUEST
IPC: A61K31/085 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/67 , A61K31/10 , A61K31/135 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/235 , A61K31/255 , A61K31/66 , A61P17/00 , A61P29/00 , A61P35/00 , A61P39/02 , A61Q19/00 , C07C39/17 , C07C43/20 , C07C43/205 , C07C43/21 , C07C43/23 , C07C45/44 , C07C47/575 , C07C49/643 , C07C59/68 , C07C59/70 , C07C63/44 , C07C65/21 , C07C65/24 , C07C65/26 , C07C69/035 , C07C69/76 , C07C69/773 , C07C69/92 , C07C69/94 , C07C205/34 , C07C205/37 , C07C211/60 , C07C215/76 , C07C217/48 , C07C217/58 , C07C217/76 , C07C217/84 , C07C217/86 , C07C219/34 , C07C223/02 , C07C223/06 , C07C225/16 , C07C225/22 , C07C229/36 , C07C229/38 , C07C229/60 , C07C233/18 , C07C233/25 , C07C233/43 , C07C233/44 , C07C233/47 , C07C233/55 , C07C233/75 , C07C233/80 , C07C235/42 , C07C237/30 , C07C239/02 , C07C239/08 , C07C255/51 , C07C255/54 , C07C259/10 , C07C309/42 , C07C309/46 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/16 , C07C323/19 , C07C323/20 , C07C323/32 , C07C323/34 , C07C323/36 , C07C323/40 , C07C323/41 , C07C323/56 , C07C323/62 , C07C327/22 , C07C327/30 , C07D257/04 , C07F9/38 , C07F9/40 , C07C , A61K
CPC classification number: C07F9/3834 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/411 , A61K8/42 , A61K8/445 , A61K8/46 , A61K8/671 , A61Q19/00 , C07C39/17 , C07C43/202 , C07C43/2055 , C07C43/21 , C07C43/23 , C07C45/44 , C07C47/575 , C07C59/70 , C07C65/24 , C07C65/26 , C07C69/76 , C07C69/92 , C07C205/34 , C07C205/37 , C07C211/60 , C07C217/48 , C07C217/58 , C07C217/76 , C07C217/86 , C07C223/06 , C07C229/38 , C07C229/60 , C07C233/18 , C07C233/25 , C07C233/43 , C07C233/47 , C07C233/75 , C07C255/54 , C07C259/10 , C07C309/42 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/16 , C07C323/19 , C07C323/20 , C07C323/32 , C07C323/34 , C07C323/36 , C07C323/41 , C07C323/56 , C07C323/62 , C07C327/30 , C07C2602/10 , C07F9/4021
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公开(公告)号：ZA9000962B
公开(公告)日：1991-10-30
申请号：ZA9000962
申请日：1990-02-09
Applicant: BASF AG
Inventor： JANSSEN BERND , BERND JANSSEN , WUEST HANS-HEINER , HANS-HEINER WUEST , MURRAY WILLIAM V , WILLIAM V MURRAY , WACHTER MICHAEL P , MICHAEL P WACHTER , BELL STANLEY , STANLEY BELL
IPC: A61K31/15 , A61K8/00 , A61K8/30 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/46 , A61K8/49 , A61K8/55 , A61K8/58 , A61K31/165 , A61K31/18 , A61K31/19 , A61K31/225 , A61K31/235 , A61K31/275 , A61K31/33 , A61K31/445 , A61K31/495 , A61K31/535 , A61K31/5375 , A61K31/54 , A61K31/66 , A61P17/00 , A61P19/06 , A61P27/02 , A61P29/00 , A61P31/04 , A61P35/00 , A61Q17/04 , A61Q19/00 , C07C243/22 , C07C251/86 , C07C251/88 , C07C255/58 , C07C255/61 , C07C255/66 , C07C259/10 , C07C309/45 , C07C309/46 , C07C311/39 , C07C317/32 , C07C323/48 , C07D211/06 , C07D215/22 , C07D215/227 , C07D241/04 , C07D295/18 , C07D295/192 , C07D295/22 , C07D295/26 , C07D311/58 , C07D317/32 , C07F9/11 , C07F9/40 , C07C , A61K , C07D
CPC classification number: C07D215/227 , C07C251/86 , C07C255/66 , C07C259/10 , C07C309/46 , C07C317/32 , C07C2601/02 , C07C2602/08 , C07C2602/10 , C07D295/192 , C07D295/26 , C07D311/58 , C07F9/4021
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公开(公告)号：ZA8901757B
公开(公告)日：1990-11-28
申请号：ZA8901757
申请日：1989-03-08
Applicant: BASF AG
Inventor： SEELE RAINER , RAINER SEELE , KARBACH STEFAN , STEFAN KARBACH , JANSSEN BERND , BERND JANSSEN , KOBER REINER , REINER KOBER , AMMERMANN EBERHARD , EBERHARD AMMERMANN , LORENZ GISELA , GISELA LORENZ
IPC: C07D405/06 , A01N43/50 , C07D405/14 , C07D521/00 , C07D , A01N
CPC classification number: C07D249/08 , A01N43/50 , C07D231/12 , C07D233/56
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公开(公告)号：HK1041007A1
公开(公告)日：2002-06-28
申请号：HK02101870
申请日：2002-03-12
Applicant: BASF AG
Inventor： KURT RITTER , BERND JANSSEN , ANDREAS HAUPT , ANDREAS KLING , TERESA BARLOZZARI , WILHELM AMBERG
IPC: A61K38/00 , C07K20060101 , A61K20060101 , A61K35/56 , A61P35/00 , C07K5/103 , C07K5/117 , C07K7/02
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Patent Agency Ranking
公开(公告)号：RU2132334C1
公开(公告)日：1999-06-27
申请号：RU95115135
申请日：1993-12-04
Applicant: BASF AG
Inventor： ANDREAS KHAUPT , BERND JANSSEN , KURT RITTER , DAGMAR KLINGE , GERKHARD KEJL KHAUER , SINTIJA ROMERDAL , TEREZA BARLOZZARI , KSIAO-DONG KVIAN
Abstract: FIELD: organic chemistry, peptides. SUBSTANCE: invention relates to peptides of the general formula (I) where R is C 1-7 -alkyl; R is C 1-4 -alkyl; X is C 1-5 -alkyl; R is a lower alkyl; B - is C 1-5 -alkyl; D is C 1-5 -alkoxy; M - phenylalanine; R - H; R - H or benzyl; d = 0 or 1, or their salts showing the improved therapeutic properties for treatment of patients with neoplasms as compared with dolostatine-10. Proposed analog can be synthesized by conventional methods unlike to the latter. EFFECT: improved therapeutic properties. 2 cl, 2 tbl, 2 ex
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公开(公告)号：ZA906201B
公开(公告)日：1992-04-29
申请号：ZA906201
申请日：1990-08-07
Applicant: BASF AG
Inventor： JANSSEN BERND , BERND JANSSEN , WUEST HANS-HEINER , HANS-HEINER WUEST
IPC: A61K31/095 , A61K8/46 , A61K31/10 , A61K31/255 , A61K31/35 , A61K31/352 , A61P17/00 , A61P35/00 , A61P37/00 , A61Q19/00 , C07C315/04 , C07C317/14 , C07C317/22 , C07C319/00 , C07C319/20 , C07C321/24 , C07C321/28 , C07C323/18 , C07D311/04 , C07D311/58 , C07C , C07D , A61K
Abstract: Diarylacetylenes of the formula I I where R1 is hydrogen or C1-C4-alkyl, R2 and R3 are each hydrogen or, when R1 is hydrogen, together form a -C(CH3)2-B-C(CH3)2- group (where B is -CH2Ch2- or -CH(CH3)-) or -OC(Ch3) (Z)CH2CH2- group (where Z is C1-C2-alkyl) or R2 is C1-C3-alkoxy and R3 is C1-C10-alkyl or, when R2 is hydrogen, R1 and R3 are each alkyl as defined above, R4 is C1-C6-alkyl and n is 0, 1 or 2, are prepared as described and used as active compounds in drugs and cosmetics.
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8.发明专利
公开(公告)号：ZA9000964B
公开(公告)日：1991-10-30
申请号：ZA9000964
申请日：1990-02-09
Applicant: BASF AG
Inventor： JANSSEN BERND , BERND JANSSEN , WUEST HANS-HEINER , HANS-HEINER WUEST
IPC: A61K31/15 , A61K20060101 , A61K8/00 , A61K8/30 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/235 , A61K31/255 , A61K31/275 , A61P17/00 , A61P27/02 , A61P29/00 , A61P31/04 , A61P35/00 , A61Q17/00 , C07C20060101 , C07C229/60 , C07C233/65 , C07C249/16 , C07C251/80 , C07C255/66 , C07C259/10 , C07C309/46 , C07C317/32 , C07C317/34 , C07C403/18 , C07C , A61K
CPC classification number: C07C403/18 , C07C2601/16
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公开(公告)号：RU2153504C2
公开(公告)日：2000-07-27
申请号：RU96123123
申请日：1995-04-26
Applicant: BASF AG
Inventor： VIL GEL M AMBERG , KHARAL D BERNARD , EHRNST BUSHMANN , ANDREAS KHAUPT , LOTAR JANICHKE , BERND JANSSEN , UL RIKH KARL , ANDREAS KLING , SHTEFAN MJULLER , BERND DEH POTTSOLLI , KURT RITTER , MARKO TIES , TOMAS TSIRKE
Abstract: medicine. SUBSTANCE: described is pentapeptide hydrochloride of formula I: Me2Val-Val-MeVai-Pro-Pro-NHBzl.HCl (I) wherein Me is methyl and Bzl is benzyl. Compound has antitumor activity. Also described are methods of preparation thereof. EFFECT: improved properties of the title compound. 6 cl, 2 ex
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公开(公告)号：RU95115135A
公开(公告)日：1997-06-10
申请号：RU95115135
申请日：1993-12-04
Applicant: BASF AG
Inventor： ANDREAS KHAUPT , BERND JANSSEN , KURT RITTER , DAGMAR KLINGE , GERKHARD KEJL KHAUER , SINTIJA ROMERDAL , TEREZA BARLOZZARI , KSIAO-DONG KVIAN
IPC: A61K38/00 , C07K5/103 , A61K38/07 , A61K38/08 , A61P35/00 , C07K1/00 , C07K5/02 , C07K5/027 , C07K7/02 , C07K7/06
Abstract: Описаныновыепептидыформулы I,вкоторойзначения R, R, X, А, R, В, D, E, R, M, Q, a, b и d указаныв описании, испособыихполучения. Новыевеществаобладаютантинеопластическимдействием.
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