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公开(公告)号：PL355487A1
公开(公告)日：2004-05-04
申请号：PL35548700
申请日：2000-10-20
Applicant: BASF AG
Inventor： KESSELER MARIA , HAUER BERNHARD , FRIEDRICH THOMAS , MATTES RALF
Abstract: The present invention relates to proteins which have an enzymatic activity for hydrolyzing L-pantolactone. The invention further relates to nucleic acids which code for these proteins, to nucleic acid constructs, vectors, genetically modified microorganisms and to a process for preparing D-pantolactone.
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公开(公告)号：HU0300155A2
公开(公告)日：2003-05-28
申请号：HU0300155
申请日：2001-02-27
Applicant: BASF AG
Inventor： ENGELS DIRK , HAUER BERNHARD , MATTES RALF , RESS-LOESCHKE MARION
Abstract: Isolated nucleic acid (I), encoding a polypeptide (II) with nitrilase activity, is (i) a 1483 bp sequence (1), reproduced; (ii) a sequence equivalent to (1) within the degeneracy of the genetic code or (iii) a derivative of (1) that encodes a polypeptide having at least 95% homology with a 366 amino acid polypeptide (2), reproduced, and essentially the same enzymatic activity as (2). Independent claims are also included for the following: (a) (II) encoded by (I); (b) nucleic acid construct containing (I) linked to one or more regulatory signals; (c) vector containing (I) or the construct of (b); (d) recombinant microorganism containing (I), the construct of (b) or the vector of (c); and (e) method for producing achiral or chiral carboxylic acids (III) by treating nitriles (IV) with (II) or with growing, resting or lysed microorganisms of (d).
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公开(公告)号：CZ20021449A3
公开(公告)日：2002-10-16
申请号：CZ20021449
申请日：2000-10-20
Applicant: BASF AG
Inventor： KESSELER MARIA , HAUER BERNHARD , FRIEDRICH THOMAS , MATTES RALF
Abstract: The present invention relates to proteins which have an enzymatic activity for hydrolyzing L-pantolactone. The invention further relates to nucleic acids which code for these proteins, to nucleic acid constructs, vectors, genetically modified microorganisms and to a process for preparing D-pantolactone.
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公开(公告)号：EE200100232A
公开(公告)日：2002-08-15
申请号：EEP200100232
申请日：1999-10-13
Applicant: BASF AG
Inventor： RESS-LOESCHKE MARION , FRIEDRICH THOMAS , HAUER BERNHARD , MATTES RALF , ENGELS DIRK
IPC: C12N15/09 , C07H21/00 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N15/63
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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公开(公告)号：ZA200104066B
公开(公告)日：2002-07-01
申请号：ZA200104066
申请日：2001-05-18
Applicant: BASF AG
Inventor： RESS-LOESCHKE MARION , FRIEDRICH THOMAS , HAUER BERNHARD , MATTES RALF , ENGELS DIRK
IPC: C07H21/00 , C12N1/21 , C12N9/78 , C12N15/09 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N , C12P , C12R
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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Patent Agency Ranking
公开(公告)号：CA2400446A1
公开(公告)日：2001-09-07
申请号：CA2400446
申请日：2001-02-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , RESS-LOSCHKE MARION , MATTES RALF , ENGELS DIRK
IPC: C12N15/09 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P41/00 , C12R1/19 , C12N15/70 , C12N15/76
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide with nitrilase activity, nucleic acid constructs containing said nucleic aci ds and vectors containing said nucleic acids or said nucleic acid constructs. T he invention also relates to amino acid sequences which are coded by the nuclei c acid sequences and micro-organisms containing said nucleic acid sequences, said nucleic acid constructs or vectors containing said nucleic acid sequenc es or said nucleic acid constructs. The invention also relates to an enzymatic method for producing carboxylic acids from the corresponding nitriles.
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公开(公告)号：ID29136A
公开(公告)日：2001-08-02
申请号：ID20010881
申请日：1999-10-13
Applicant: BASF AG
Inventor： RESS-LOSCHKE MARION , FRIEDRICH THOMAS , HAUER BERNHARD , MATTES RALF , ENGELS DIRK
IPC: C07H21/00 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N15/09 , C12N15/63
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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公开(公告)号：BR9914629A
公开(公告)日：2001-06-26
申请号：BR9914629
申请日：1999-10-13
Applicant: BASF AG
Inventor： RESS LOSCHKE MARION , FRIEDRICH THOMAS , HAUER BERNHARD , MATTES RALF , ENGELS DIRK
IPC: C12N15/09 , C07H21/00 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N15/63
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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公开(公告)号：CA2389064A1
公开(公告)日：2001-05-10
申请号：CA2389064
申请日：2000-10-20
Applicant: BASF AG
Inventor： KESSELER MARIA , MATTES RALF , FRIEDRICH THOMAS , HAUER BERNHARD
Abstract: The invention relates to proteins which have an enzymatic activity for hydrolysing L-pantolactone. The invention also relates to nucleic acids that code for these proteins, to nucleic acid constructs, to vectors, to genetically modified micro-organisms and to a method for producing D- pantolactone.
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公开(公告)号：AT349517T
公开(公告)日：2007-01-15
申请号：AT99952558
申请日：1999-10-13
Applicant: BASF AG
Inventor： RESS-LOESCHKE MARION , FRIEDRICH THOMAS , HAUER BERNHARD , MATTES RALF , ENGELS DIRK
IPC: C12N15/09 , C07H21/00 , C12N1/21 , C12N9/78 , C12N15/55 , C12P7/40 , C12P7/42 , C12P41/00 , C12R1/05 , C12N15/63
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
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