公开(公告)号：DE102005060803A1

公开(公告)日：2007-06-28

申请号：DE102005060803

申请日：2005-12-20

Applicant: BASF AG

Inventor： ERNST MARTIN ,  KUSCHE ANDREAS ,  HEYDRICH GUNNAR ,  GRAFMANS HORST ,  EVERS HOLGER ,  MELDER JOHANN-PETER ,  MEISNER HARALD ,  FREUND TORSTEN

IPC: C07C231/06

Abstract: Preparation of aminoalkanoic acid amide comprises reaction of cyanoalkanoic acid ester with (a) at least a mol-equivalent of ammonia or amine, and (b) hydrogen in the presence of catalyst, at increased pressure, where optionally the formed intermediate stages are not isolated and the reaction with (b) takes place simultaneously or less than 100 minutes, after the beginning of the reaction of cyanoalkanoic acid ester with (a).

公开(公告)号：DE102005044090A1

公开(公告)日：2007-03-22

申请号：DE102005044090

申请日：2005-09-15

Applicant: BASF AG

Inventor： EVERS HOLGER ,  MELDER JOHANN-PETER ,  PREISS THOMAS ,  MEISNER HARALD

IPC: C07C253/30 ,  C07B43/04 ,  C07C227/06 ,  C07C229/00 ,  C07C255/24

Abstract: Preparation of beta -aminopropionic acid derivatives by reacting primary/secondary amine with an acrylic acid derivative, comprises reacting first primary or secondary amine with acrylic acid derivative to obtain a first beta -aminopropionic acid derivative and unreacted acrylic acid derivative; and completely reacting the unreacted acrylic acid derivative with a second secondary amine to obtain a second beta -aminopropionic acid derivative, where the reaction mixture contains beta -aminopropionic acid derivative and unreacted secondary amine. Preparation of beta -aminopropionic acid derivatives by reacting a primary/ secondary amine with an acrylic acid derivative, comprises reacting first primary or secondary amine as value amine with acrylic acid derivative to obtain reaction mixture containing a first beta -aminopropionic acid derivative as an end product in addition with unreacted acrylic acid derivative, where the amount of the acrylic acid derivative is large, when compared with the value amine; and completely reacting the unreacted acrylic acid derivative with a second secondary amine as a trapping amine to obtain a second beta -aminopropionic acid derivative, where the reaction mixture contains first beta -aminoproionic acid derivative as end product, second beta -aminopropionic acid derivative and unreacted secondary amine.