公开(公告)号：ES2187678T3

公开(公告)日：2003-06-16

申请号：ES96934494

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JURGEN ,  ROSENBERG JOERG ,  NEUMANN JORG ,  BREITENBACH JORG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：CA2230950C

公开(公告)日：2007-12-04

申请号：CA2230950

申请日：1996-09-30

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  ROSENBERG JOERG ,  ZEIDLER JURGEN ,  NEUMANN JORG

IPC: A61K9/20 ,  A61J3/06 ,  A61K9/16 ,  A61K31/275 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30 ,  A61K47/34 ,  A61K47/38

Abstract: The invention concerns solid medicaments obtained by extrusion with subseque nt shaping of a solvent-free melt, containing in addition to one or a plurality of active substances: A) between 10 and 90 wt.% of a thermoplastically processable water-soluble polymer, B) between and 85 wt.% isomalt; and C) between 0 and 5 wt.% lecithin, the total of all the contents equalling 100 wt.%.

公开(公告)号：AU7282896A

公开(公告)日：1997-04-28

申请号：AU7282896

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JURGEN ,  ROSENBERG JOERG ,  NEUMANN JORG ,  BREITENBACH JORG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：CA2298659C

公开(公告)日：2007-09-11

申请号：CA2298659

申请日：1998-07-21

Applicant: BASF AG

Inventor： NEUMANN JORG ,  LIEPOLD BERND ,  VOLLGRAF CHRISTIANE ,  ROSENBERG JORG ,  ZEIDLER JURGEN ,  BREITENBACH JORG ,  BERNDL GUNTHER

IPC: A61K31/192 ,  A61J3/00 ,  A61K9/20 ,  A61K47/02 ,  A61K47/22 ,  A61K47/32 ,  A61P29/00

Abstract: The invention relates to a fast acting analgesic, containing ibuprofen as th e active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.

公开(公告)号：EA002853B1

公开(公告)日：2002-10-31

申请号：EA200000132

申请日：1998-07-21

Applicant: BASF AG

Inventor： ZEIDER JURGEN ,  NEUMANN JORG ,  LIEPOLD BERND ,  ROSENBERG JOERG ,  BERNDL GUNTHER ,  BREITENBACH JORG ,  VOLLGRAF CHRISTIANE

IPC: A61K9/20 ,  A61K31/192 ,  A61K47/02 ,  A61K47/32 ,  A61P29/00 ,  A61P29/02

Abstract: Настоящееизобретениеотноситсяк быстродействующемуобезболивающемупрепарату, содержащемув качествеобезболивающеговеществаибупрофенв матрицевспомогательныхвеществи имеющемупористуюструктуруи плотностьотболее 1 г/смидо 2,5 г/см. Изобретениетакжеотноситсяк способуполучениятакогопрепарата.

公开(公告)号：CA2298659A1

公开(公告)日：1999-02-11

申请号：CA2298659

申请日：1998-07-21

Applicant: BASF AG

Inventor： ZEIDLER JURGEN ,  ROSENBERG JORG ,  BREITENBACH JORG ,  BERNDL GUNTHER ,  VOLLGRAF CHRISTIANE ,  NEUMANN JORG ,  LIEPOLD BERND

IPC: A61K9/20 ,  A61K31/192 ,  A61K47/02 ,  A61K47/32 ,  A61P29/00 ,  A61K31/19

Abstract: The invention relates to a fast-acting analgesic, containing ibuprofen as the active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.