公开(公告)号：AT20345T

公开(公告)日：1986-06-15

申请号：AT83103054

申请日：1983-03-28

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER DR

IPC: A61K31/55 ,  A61P1/04 ,  C07D223/20

公开(公告)号：DE3171074D1

公开(公告)日：1985-07-25

申请号：DE3171074

申请日：1981-12-23

Applicant: BASF AG

Inventor： THIEME PETER C DR ,  STEINER GERD DR ,  ROHR WOLFGANG DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  WEIFENBACH HARALD DR ,  TESCHENDORF HANS-JUERGEN DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

公开(公告)号：GR81309B

公开(公告)日：1984-12-11

申请号：GR810165114

申请日：1981-06-01

Applicant: BASF AG

Inventor： THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  LENKE DIETER DR ,  LEHMANN HANS DIETER DR ,  GRIES JOSEF DR

IPC: A61K31/50 ,  C07D237/04

Abstract: Novel 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are substituted in the p-position of the phenyl ring by a carbamate or thiocarbamate group, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders, and as anti-hypertensives.

公开(公告)号：DE3162110D1

公开(公告)日：1984-03-08

申请号：DE3162110

申请日：1981-06-29

Applicant: BASF AG

Inventor： EILINGSFELD HEINZ DR ,  NEUMANN PETER DR ,  SEYBOLD GUENTHER DR ,  LENKE DIETER DR ,  FRIEDRICH LUDWIG DR

IPC: A61K31/425 ,  A61K31/428 ,  A61P37/08 ,  C07D277/60 ,  C07D277/82

公开(公告)号：DE3328438A1

公开(公告)日：1984-02-16

申请号：DE3328438

申请日：1983-08-06

Applicant: BASF AG

Inventor： EILINGSFELD HEINZ DR ,  NEUMANN PETER DR ,  SCHLECKER RAINER DR ,  LENKE DIETER DR ,  FRIEDRICH LUDWIG DR

IPC: C07D275/06 ,  C07D277/82 ,  A61K31/215 ,  A61K31/425 ,  A61K31/445 ,  C07D275/04

Abstract: Novel oxamic acid esters, a process for their preparation and therapeutic compositions containing these, which can be used in the treatment of allergic diseases.

公开(公告)号：CH638186A5

公开(公告)日：1983-09-15

申请号：CH278478

申请日：1978-03-14

Applicant: BASF AG

Inventor： PHILIPSBORN GERDA VON DR ,  BOELL WALTER DR ,  LENKE DIETER DR

IPC: A61C8/00 ,  A61K31/435 ,  A61K31/44 ,  A61K31/4406 ,  A61K31/4415 ,  A61K31/4418 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/455 ,  A61K31/495 ,  A61K31/496 ,  A61P9/00 ,  A61P9/04 ,  A61P9/06 ,  C07D213/127 ,  C07D213/65 ,  C07D213/66 ,  C07D213/67 ,  C07D213/79 ,  C07D213/80 ,  C07D221/04 ,  C07D263/32 ,  C07D401/12 ,  C07D471/04 ,  C07D491/04 ,  C07D491/048 ,  C07D491/056

公开(公告)号：DE3064096D1

公开(公告)日：1983-08-18

申请号：DE3064096

申请日：1980-05-05

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  TESCHENDORF HANS-JUERGEN DR ,  WORSTMANN WOLFGANG DR ,  KREISKOTT HORST DR

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.

公开(公告)号：CH635086A5

公开(公告)日：1983-03-15

申请号：CH122478

申请日：1978-02-03

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER DR ,  HAGEN HELMUT DR ,  OHNSORGE ULRICH DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER DR

IPC: A61K31/428 ,  C07D275/04 ,  A61K31/425

公开(公告)号：CH621546A5

公开(公告)日：1981-02-13

申请号：CH802076

申请日：1976-06-23

Applicant: BASF AG

Inventor： WEITZ HANS-MARTIN DR ,  FISCHER ROLF DR ,  LENKE DIETER DR

IPC: C07D253/10 ,  C07D253/08

Abstract: 1,2,4-Dihydrotriazine-4-oxide-spiro-(3,1')-[oximino-(2')-cycloalkanes] are manufactured by reaction of oximinocycloalk-1-enes, substituted in the 1-position, with hydrazine. The products, especially the triazine derivative described in Example 1, possess antiphlogistic properties and are starting materials for the manufacture of dyes and pharmaceuticals.

公开(公告)号：DE2860232D1

公开(公告)日：1980-12-04

申请号：DE2860232

申请日：1978-07-26

Applicant: BASF AG

Inventor： HAGEN HELMUT DR ,  LENKE DIETER DR ,  VON PHILIPSBORN GERDA DR

IPC: A61K31/425 ,  A61K31/505 ,  C07D275/04 ,  C07D417/10

Abstract: 3-[4-(1,3-Diazacyclo-2-yl)]-1,2-benzisothiazoles, their addition salts with acids, their manufacture, and pharmaceutical formulations which contain these compounds as active ingredients and which may be used for the pharmacotherapy of cardiac arrhythmias.