公开(公告)号：ZA9809571B

公开(公告)日：2000-04-25

申请号：ZA9809571

申请日：1998-10-21

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  DULLWEBER UTA ,  STARCK DOROTHEA ,  STEINER GERD ,  BACH ALFRED ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  TESCHENDORF HANS JUERGEN ,  WICKE KARSTEN

IPC: A61K31/428 ,  A61P25/24 ,  A61P43/00 ,  C07D275/06 ,  C07D417/04 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D ,  A61K

CPC classification number: C07D275/06 ,  C07D417/04 ,  C07D417/06 ,  C07D417/12

公开(公告)号：ZA989571B

公开(公告)日：2000-04-25

申请号：ZA989571

申请日：1998-10-21

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  DULLWEBER UTA ,  STARCK DOROTHEA ,  STEINER GERD ,  BACH ALFRED ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  TESCHENDORF HANS JUERGEN ,  WICKE KARSTEN

IPC: A61K31/428 ,  A61P25/24 ,  A61P43/00 ,  C07D275/06 ,  C07D417/04 ,  C07D417/06 ,  C07D417/12 ,  C07D417/14 ,  C07D ,  A61K

Abstract: where the substituents have the meanings indicated in the description, their preparation and use as serotonin antagonists.

公开(公告)号：ZA9809664B

公开(公告)日：2000-04-25

申请号：ZA9809664

申请日：1998-10-23

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  DULLWEBER UTA ,  STARCK DOROTHEA ,  STEINER GERD ,  BACH ALFRED ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  TESCHENDORF HANS JUERGEN ,  WICKE KARSTEN

IPC: A61K31/519 ,  A61P1/00 ,  A61P1/14 ,  A61P3/04 ,  A61P5/00 ,  A61P9/12 ,  A61P15/00 ,  A61P25/00 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P43/00 ,  C07D471/04 ,  C07D ,  A61K

CPC classification number: C07D471/04

公开(公告)号：MX9204119A

公开(公告)日：1994-01-31

申请号：MX9204119

申请日：1992-07-14

Applicant: BASF AG

Inventor： MUELLER BEATRICE RENDENBACH ,  TESCHENDORF HANS JUERGEN ,  UNGER LILLIANE

IPC: A61K31/425

公开(公告)号：ZA82293B

公开(公告)日：1982-12-29

申请号：ZA82293

申请日：1982-01-18

Applicant: BASF AG

Inventor： THIEME PETER C ,  STEINER GERD ,  ROHR WOLFGANG ,  LENKE DIETER ,  GRIES JOSEF ,  WEIFENBACH HARALD ,  TESCHENDORF HANS JUERGEN ,  HOFMANN HANS PETER ,  KREISKOTT HORST

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00 ,  A61K ,  C07C ,  C07D

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

公开(公告)号：ZA8200293B

公开(公告)日：1982-12-29

申请号：ZA8200293

申请日：1982-01-18

Applicant: BASF AG

Inventor： THIEME PETER C ,  STEINER GERD ,  ROHR WOLFGANG ,  LENKE DIETER ,  GRIES JOSEF ,  WEIFENBACH HARALD ,  TESCHENDORF HANS JUERGEN ,  HOFMANN HANS PETER ,  KREISKOTT HORST

IPC: C07D249/08 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00 ,  A61K ,  C07C ,  C07D

CPC classification number: C07D271/10 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D295/067 ,  C07D295/096

公开(公告)号：MX9204118A

公开(公告)日：1994-01-31

申请号：MX9204118

申请日：1992-07-14

Applicant: BASF AG

Inventor： RENDENBACH-MUELLER BEATRICE ,  TESCHENDORF HANS JUERGEN ,  UNGER LILIANE

IPC: C07D275/02

公开(公告)号：ZA82294B

公开(公告)日：1982-12-29

申请号：ZA82294

申请日：1982-01-18

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  STEINER GERD ,  THIEME PETER C ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS JUERGEN

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  A61K ,  C06D

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：ZA8200294B

公开(公告)日：1982-12-29

申请号：ZA8200294

申请日：1982-01-18

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  STEINER GERD ,  THIEME PETER C ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS JUERGEN

IPC: C07D249/08 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  A61K ,  C06D

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D239/42 ,  C07D249/08 ,  C07D261/08 ,  C07D295/088 ,  Y10S514/923

公开(公告)号：ZA8106927B

公开(公告)日：1982-10-27

申请号：ZA8106927

申请日：1981-10-07

Applicant: BASF AG

Inventor： STEINER GERD ,  TESCHENDORF HANS JUERGEN ,  KREISKOTT HORST ,  HOFMANN HANS PETER

IPC: A61K31/55 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  C07D495/14 ,  C07D

CPC classification number: C07D495/14