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1.发明申请METHODS AND COMPOSITIONS UTILIZING HYBRID EXACT ROTAMER OPTIMIZATION ALGORITHMS FOR PROTEIN DESIGN 审中-公开用于蛋白质设计的混合优化旋转优化算法的方法和组合
公开(公告)号：WO0190960A2
公开(公告)日：2001-11-29
申请号：PCT/US0117025
申请日：2001-05-24
Applicant: CALIFORNIA INST OF TECHN , PIERCE NILES A , GORDON DAVID BENJAMIN , MAYO STEPHEN
Inventor： PIERCE NILES A , GORDON DAVID BENJAMIN , MAYO STEPHEN
CPC classification number: G06F19/16
Abstract: The present invention relates to an apparatus and method for quantitative protein design and optimization. In particular, the invention describes the use of Hybrid Exact Rotamer Optimization algorithms in protein design.
Abstract translation: 本发明涉及定量蛋白质设计和优化的装置和方法。 特别地，本发明描述了在蛋白质设计中使用混合精确旋转优化算法。
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2.发明公开
公开(公告)号：EP1030733A4
公开(公告)日：2000-08-30
申请号：EP98906253
申请日：1998-02-05
Applicant: CALIFORNIA INST OF TECHN
Inventor： DESAI AMISH , YANG XING , TAI YU-CHONG , MARZLUFF ELAINE , BOCKENKAMP DIRK , MAYO STEPHEN
CPC classification number: B01L3/5027 , B01F5/0256 , B01F5/0602 , B01F13/0059 , B01F2005/0025 , B01F2005/0621 , B01J19/0093 , B01J2219/00783 , B01J2219/00797 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , B01L2400/0487 , B01L2400/084 , Y10S366/03
Abstract: A micromachined, high Reynolds number, sub-millisecond liquid mixer for the study of chemical reaction kinetics. This bulk micromachined silicon mixer is capable of initiating and quenching chemical reactions in intervals as short as 100 νs. The mixer chip contains two tee mixers (120, 130) connected by one channel which serves a reaction chamber (140). Each tee mixer consists of opposing channels (110, 120) where liquids meet head-on and exit into a third channel (150) forming the base of a 'T'.
Abstract translation: 用于研究化学反应动力学的微机械高雷诺数亚毫秒液体混合器。 这种大型微机械硅混合器能够以100νs的间隔启动和熄灭化学反应。 混合器芯片包含两个T形混合器（120,130），其通过一个用于反应室（140）的通道连接。 每个T形混合器由相对的通道（110,120）组成，在这些通道中液体迎头相接并流出到形成“T”的基部的第三通道（150）中。
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公开(公告)号：AU6152498A
公开(公告)日：1998-08-25
申请号：AU6152498
申请日：1998-02-05
Applicant: CALIFORNIA INST OF TECHN
Inventor： DESAI AMISH , YANG XING , TAI YU-CHONG , MARZLUFF ELAINE , BOCKENKAMP DIRK , MAYO STEPHEN
Abstract: A micromachined, high Reynolds number, sub-millisecond liquid mixer for the study of chemical reaction kinetics. This bulk micromachined silicon mixer is capable of initiating and quenching chemical reactions in intervals as short as 100 mu s. The mixer chip contains two tee mixers connected by one channel which serves as a reaction chamber. Each tee mixer consists of opposing channels where liquids meet head-on and exit into a third channel forming the base of a "T".
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公开(公告)号：AU6965498A
公开(公告)日：1998-11-11
申请号：AU6965498
申请日：1998-04-10
Applicant: CALIFORNIA INST OF TECHN
Inventor： MAYO STEPHEN , DAHIYAT BASSIL I , GORDON D BENJAMIN , STREET ARTHUR
IPC: C12N15/09 , C07K1/00 , C07K14/00 , C12N1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/10 , G06F17/50 , G06F19/16 , G06F19/18 , G06F19/22
Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
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公开(公告)号：AU2002302138B2
公开(公告)日：2005-06-23
申请号：AU2002302138
申请日：2002-11-15
Applicant: CALIFORNIA INST OF TECHN
Inventor： STREET ARTHUR , GORDON D BENJAMIN , DAHIYAT BASSIL I , MAYO STEPHEN
IPC: G06F017/50 , C07K001/00
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Patent Agency Ranking
公开(公告)号：AU751331B2
公开(公告)日：2002-08-15
申请号：AU6965498
申请日：1998-04-10
Applicant: CALIFORNIA INST OF TECHN
Inventor： MAYO STEPHEN , DAHIYAT BASSIL I , GORDON D BENJAMIN , STREET ARTHUR
IPC: C12N15/09 , C07K1/00 , C07K14/00 , C12N1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/10 , G06F17/50 , G06F19/16 , G06F19/18 , G06F19/22
Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
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7.发明专利
公开(公告)号：AU6344501A
公开(公告)日：2001-12-03
申请号：AU6344501
申请日：2001-05-24
Applicant: CALIFORNIA INST OF TECHN
Inventor： PIERCE NILES A , GORDON DAVID BENJAMIN , MAYO STEPHEN
Abstract: The present invention relates to an apparatus and method for quantitative protein design and optimization. In particular, the invention describes the use of Hybrid Exact Rotamer Optimization algorithms in protein design.
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公开(公告)号：AU2005211654B2
公开(公告)日：2006-09-07
申请号：AU2005211654
申请日：2005-09-22
Applicant: CALIFORNIA INST OF TECHN
Inventor： DAHIYAT BASSIL I , STREET ARTHUR , MAYO STEPHEN , GORDON BENJAMIN
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公开(公告)号：AU2005211654A1
公开(公告)日：2005-10-13
申请号：AU2005211654
申请日：2005-09-22
Applicant: CALIFORNIA INST OF TECHN
Inventor： DAHIYAT BASSIL I , STREET ARTHUR , MAYO STEPHEN , GORDON BENJAMIN
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公开(公告)号：DE69810603T2
公开(公告)日：2003-11-13
申请号：DE69810603
申请日：1998-04-10
Applicant: CALIFORNIA INST OF TECHN
Inventor： MAYO STEPHEN , DAHIYAT I , GORDON BENJAMIN , STREET ARTHUR
IPC: C12N15/09 , C07K1/00 , C07K14/00 , C12N1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/10 , G06F17/50 , G06F19/16 , G06F19/18 , G06F19/22
Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
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