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公开(公告)号：WO2019118339A1
公开(公告)日：2019-06-20
申请号：PCT/US2018/064730
申请日：2018-12-10
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MYERS, Carl , PICQUET, Guillaume , MAKWANA, Ekta
CPC classification number: A61K8/24 , A61K8/41 , A61K8/44 , A61K8/4926 , A61K8/8147 , A61K8/86 , A61K8/90 , A61K2800/43 , A61K2800/52 , A61K2800/592 , A61K2800/594 , A61Q11/00
Abstract: This application provides, among other things, novel aqueous monophasic compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.
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公开(公告)号：WO2022098730A1
公开(公告)日：2022-05-12
申请号：PCT/US2021/057861
申请日：2021-11-03
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MANUS, Lisa , STEELE, Joseph , PICQUET, Guillaume , PADULA, Christine , CHEN, Dandan , WON, Betty , POTANIN, Andrei
Abstract: The present invention relates to oral hydrogel compositions, more particularly to thermosensitive gel compositions, which undergo a sol-gel transition in the oral cavity, and which optionally comprise therapeutic actives for sustained release.
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公开(公告)号：WO2019040545A1
公开(公告)日：2019-02-28
申请号：PCT/US2018/047406
申请日：2018-08-22
Inventor： MYERS, Carl , PICQUET, Guillaume , UHRICH, Kathryn , CHAN WOO, Jennifer , MARINE, Jeannette Elizabeth
Abstract: Described herein are oral care compositions comprising amphiphilic macromolecules, along with methods of making and using same.
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公开(公告)号：WO2013096182A2
公开(公告)日：2013-06-27
申请号：PCT/US2012/070062
申请日：2012-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： JARACZ, Stanislav , XU, Guofeng , MILLER, Steven , LEIGH, Leonora , PICQUET, Guillaume , DU-THUMM, Laurence
IPC: A61K8/37 , A61K31/235 , A61K31/166 , C07C69/88 , C07C235/54 , A61K8/42 , A61Q11/00 , A61P31/04 , A61P17/10 , A61P17/02 , A61P29/00 , A61K8/67 , A61K8/66
CPC classification number: A61Q11/00 , A61K8/37 , A61K8/375 , A61K8/42 , A61K31/166 , A61K31/235 , A61Q17/005 , C07C69/84 , C07C235/54 , C07C2601/14 , C07C2602/08
Abstract: Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same.
Abstract translation: 本文描述的是用于局部使用的组合物，其包含抗菌有效浓度的没食子酸酯或胆酰胺化合物，其为多取代的环烷基或杂环烷基，其中取代基选自羟基，羟甲基，氟，氯，氨基，硝基或式-X - （CO） - （3,4,5-三羟基苯基），其中X选自O和NH，条件是取代基包含至少两个式-X-（CO） - （3,4,5-三羟基苯基 ）以游离或口服或局部可接受的盐形式附着在相邻的碳上，以及制备和使用它们的方法。
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5.发明申请MOUTHWASH COMPOSITION COMPRISING A PEROXIDE SOURCE AND AN N-ACYL-L-ARGININE ALKYL ESTER SALT 审中-公开包含过氧化物源和N-亚氨基-L-阿魏酸盐酸盐盐的盐酸盐组合物
公开(公告)号：WO2016028265A1
公开(公告)日：2016-02-25
申请号：PCT/US2014/051562
申请日：2014-08-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： AHMED, Rabab , MILLER, Jeffrey , PRENCIPE, Michael , PICQUET, Guillaume
Abstract: Provided herein is an aqueous mouthwash formulation comprising a salt of an Nα-acyl-L-arginine alkyl ester and a peroxide source. The mouthwash formulation provides anti-microbial activity and whitening activity.
Abstract translation: 本文提供了含有Nα-酰基-L-精氨酸烷基酯和过氧化物源的盐的含水漱口剂制剂。 漱口剂配方提供抗微生物活性和增白活性。
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Patent Agency Ranking
公开(公告)号：WO2014098868A1
公开(公告)日：2014-06-26
申请号：PCT/US2012/070952
申请日：2012-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： PATEL, Madhusudan , PICQUET, Guillaume , VANDEVEN, Mark , HASSAN, Mahmoud , PAREDES, Rosa
CPC classification number: A61K8/416 , A61K8/368 , A61K8/466 , A61K8/4926 , A61K31/095 , A61K31/14 , A61K31/60 , A61K45/06 , A61K2800/30 , A61Q11/00 , A61K2300/00
Abstract: An oral care composition is provided wherein the composition comprises an ionic liquid, wherein the ionic liquid comprises: a) a quaternary ammonium cation of the formula wherein R 1 , R 2 , R 3 and R 4 are each an organic moiety and may be the same or different, and at least one of R 1 , R 2 , R 3 and R 4 includes a hydroxyl; and b) an anion selected from the group consisting of salicylate, alkylsulfate, sulfate, acetate, halide, phosphate, alkyl phosphate and tosylate; wherein the oral care composition is a mouth rinse, toothpaste, toothpowder, oral bead or strip, fluid-encased dental strip, irrigation fluid, plaque removal liquid, dental floss, hard candy, soft candy, lozenge, chewing gum, or lollipop.
Abstract translation: 提供一种口腔护理组合物，其中所述组合物包含离子液体，其中所述离子液体包含：a）下式的季铵阳离子其中R 1，R 2，R 3和R 4各自为有机部分，并且可以相同或不同， 并且R 1，R 2，R 3和R 4中的至少一个包括羟基; 和b）选自水杨酸盐，烷基硫酸盐，硫酸盐，乙酸盐，卤化物，磷酸盐，磷酸烷基酯和甲苯磺酸盐的阴离子; 其中所述口腔护理组合物是口腔清洁剂，牙膏，牙粉，口腔珠或条，流体包裹的牙带，冲洗液，牙斑去除液，牙线，硬糖，软糖，锭剂，口香糖或棒棒糖。
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公开(公告)号：EP2934463A1
公开(公告)日：2015-10-28
申请号：EP12815937.3
申请日：2012-12-20
Applicant: Colgate-Palmolive Company
Inventor： PATEL, Madhusudan , PICQUET, Guillaume , VANDEVEN, Mark , HASSAN, Mahmoud , PAREDES, Rosa
CPC classification number: A61K8/416 , A61K8/368 , A61K8/466 , A61K8/4926 , A61K31/095 , A61K31/14 , A61K31/60 , A61K45/06 , A61K2800/30 , A61Q11/00 , A61K2300/00
Abstract: An oral care composition is provided wherein the composition comprises an ionic liquid, wherein the ionic liquid comprises: a) a quaternary ammonium cation of the formula wherein R1, R2, R3 and R4 are each an organic moiety and may be the same or different, and at least one of R1, R2, R3 and R4 includes a hydroxyl; and b) an anion selected from the group consisting of salicylate, alkylsulfate, sulfate, acetate, halide, phosphate, alkyl phosphate and tosylate; wherein the oral care composition is a mouth rinse, toothpaste, toothpowder, oral bead or strip, fluid-encased dental strip, irrigation fluid, plaque removal liquid, dental floss, hard candy, soft candy, lozenge, chewing gum, or lollipop.
Abstract translation: 提供口腔护理组合物，其中所述组合物包含离子液体，其中所述离子液体包含：a）下式的季铵阳离子：其中R 1，R 2，R 3和R 4各自是有机部分，并且可以是 相同或不同，并且R 1，R 2，R 3和R 4中的至少一个包括羟基; 和b）选自水杨酸盐，烷基硫酸盐，硫酸盐，乙酸盐，卤化物，磷酸盐，烷基磷酸盐和甲苯磺酸盐的阴离子; 其中口腔护理组合物是口腔清洗剂，牙膏，牙粉，口腔珠或带，流体包裹的牙带，冲洗液，牙斑清除液，牙线，硬糖，软糖，锭剂，口香糖或棒棒糖。
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公开(公告)号：EP3654934A1
公开(公告)日：2020-05-27
申请号：EP18765252.4
申请日：2018-08-22
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9.发明公开MOUTHWASH COMPOSITION COMPRISING A PEROXIDE SOURCE AND AN N-ACYL-L-ARGININE ALKYL ESTER SALT 审中-公开包含过氧化物源和N-酰基-L-精氨酸烷基酯盐的漱口水组合物
公开(公告)号：EP3182956A1
公开(公告)日：2017-06-28
申请号：EP14781697.9
申请日：2014-08-18
Applicant: Colgate-Palmolive Company
Inventor： AHMED, Rabab , MILLER, Jeffrey , PRENCIPE, Michael , PICQUET, Guillaume
Abstract: Provided herein is an aqueous mouthwash formulation comprising a salt of an Nα-acyl-L-arginine alkyl ester and a peroxide source. The mouthwash formulation provides anti-microbial activity and whitening activity.
Abstract translation: 本文提供含有Nα-酰基-L-精氨酸烷基酯的盐和过氧化物源的含水漱口剂制剂。 漱口水配方提供抗微生物活性和美白活性。
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公开(公告)号：EP4199883A1
公开(公告)日：2023-06-28
申请号：EP21815053.0
申请日：2021-11-03
Applicant: Colgate-Palmolive Company
Inventor： MANUS, Lisa , STEELE, Joseph , PICQUET, Guillaume , PADULA, Christine , CHEN, Dandan , WON, Betty , POTANIN, Andrei
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