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公开(公告)号：AU1799902A
公开(公告)日：2002-05-15
申请号：AU1799902
申请日：2001-11-01
Applicant: COR THERAPEUTICS INC
Inventor： KANTER JAMES , PANDEY ANJALI , ROBINSON JAMES , SCARBOROUGH ROBERT M JR
IPC: C07D239/86 , A61K31/517 , A61K31/5377 , A61P9/10 , A61P13/12 , A61P29/00 , A61P35/00 , A61P43/00 , C07B61/00 , C07D239/94 , C07D403/00
Abstract: The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.
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公开(公告)号：AU9320801A
公开(公告)日：2002-03-04
申请号：AU9320801
申请日：2001-08-17
Applicant: COR THERAPEUTICS INC , KYOWA HAKKO KOGYO KK
Inventor： PANDEY ANJALI , SCARBOROUGH ROBERT M JR , MATSUNO KENJI , ICHIMURA MICHIO , NOMOTO YUGI , FUJIWARA SHIGEKI , IDE SHINICHI , TSUKIDA EIJI , IRIE JUNKO , ODA SHOJI
IPC: A61P35/00 , C07D239/94 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D487/00
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公开(公告)号：AU5041300A
公开(公告)日：2000-12-12
申请号：AU5041300
申请日：2000-05-24
Applicant: COR THERAPEUTICS INC
Inventor： ZHU BING-YAN , ZHANG PENGLIE , SCARBOROUGH ROBERT M JR
IPC: C07D213/74 , A61K31/18 , A61K31/198 , A61K31/341 , A61K31/397 , A61K31/40 , A61K31/401 , A61K31/4164 , A61K31/44 , A61K31/4406 , A61K31/4427 , A61K31/4453 , A61K31/472 , A61K31/4725 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/55 , A61P7/02 , A61P9/00 , A61P9/10 , A61P43/00 , C07C311/16 , C07C311/21 , C07C311/46 , C07D205/04 , C07D207/16 , C07D207/20 , C07D207/325 , C07D213/40 , C07D213/64 , C07D213/72 , C07D213/75 , C07D213/82 , C07D217/22 , C07D231/12 , C07D233/68 , C07D295/18 , C07D295/192 , C07D295/22 , C07D295/26 , C07D307/38 , C07D307/52 , C07D401/12 , A61K31/33 , C07D333/20
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公开(公告)号：AU4166400A
公开(公告)日：2000-08-29
申请号：AU4166400
申请日：2000-02-11
Applicant: COR THERAPEUTICS INC
Inventor： SONG YOUNGHONG , SCARBOROUGH ROBERT M JR , ZHU BING-YAN
IPC: C07D295/14 , A61K31/18 , A61K31/192 , A61K31/195 , A61K31/216 , A61K31/341 , A61K31/40 , A61K31/41 , A61K31/415 , A61K31/4174 , A61K31/44 , A61K31/4409 , A61K31/472 , A61K31/4725 , A61K31/495 , A61K31/505 , A61K31/517 , A61P7/00 , A61P7/02 , A61P7/04 , A61P9/00 , A61P9/10 , A61P11/00 , A61P31/04 , A61P43/00 , C07C257/18 , C07C311/29 , C07C311/46 , C07C311/51 , C07D213/56 , C07D213/58 , C07D213/70 , C07D213/74 , C07D213/75 , C07D217/22 , C07D231/12 , C07D233/61 , C07D239/42 , C07D239/94 , C07D257/04 , C07D295/16 , C07D307/54 , C07D401/12 , C07D521/00
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公开(公告)号：AU6896298A
公开(公告)日：1998-11-11
申请号：AU6896298
申请日：1998-04-13
Applicant: COR THERAPEUTICS INC
Inventor： ZHU BING-YAN , SCARBOROUGH ROBERT M JR , SU TING
IPC: A61K38/00 , A61K8/63 , A61P7/02 , A61P9/02 , A61P9/10 , A61Q7/00 , A61Q7/02 , C07K5/02 , C07K5/06 , C07K5/062 , C07K5/072 , C07K5/078 , A61K38/05
Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
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Patent Agency Ranking
公开(公告)号：AU5596298A
公开(公告)日：1998-07-03
申请号：AU5596298
申请日：1997-12-08
Applicant: COR THERAPEUTICS INC , LILLY CO ELI
Inventor： FISHER MATTHEW J , FRANCISKOVICH JEFFRY BERNARD , JAKUBOWSKI JOSEPH A , MASTERS JOHN J , SCARBOROUGH ROBERT M JR , SMYTH MARK , SU TING
IPC: A61K31/197 , A61K31/27 , A61K31/445 , A61P9/10 , C07C311/06 , C07C311/19 , C07D211/60 , C07D211/62 , C07C311/00 , A61K31/18 , C07D211/04
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公开(公告)号：AU6590296A
公开(公告)日：1996-12-30
申请号：AU6590296
申请日：1996-06-05
Applicant: COR THERAPEUTICS INC
Inventor： MARLOWE CHARLES K , SCARBOROUGH ROBERT M JR , LAIBELMAN ALAN M , SINHA UMA , ZHU BING-YAN
IPC: A61K38/00 , A61P7/02 , C07C279/24 , C07C281/06 , C07C309/30 , C07C335/38 , C07K5/06 , C07K5/068 , C07K5/072 , C07K5/08 , A61K38/55
Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
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公开(公告)号：AU4939701A
公开(公告)日：2001-10-08
申请号：AU4939701
申请日：2001-03-26
Applicant: COR THERAPEUTICS INC
Inventor： MARLOWE CHARLES K , KANE-MAGUIRE KIM A , ZHU BING-YAN , SCARBOROUGH ROBERT M JR
IPC: A61P7/02 , C07D401/12 , C07D209/00
Abstract: Novel compounds of formula I:including its pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa is described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
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9.发明专利
公开(公告)号：AU1244001A
公开(公告)日：2001-05-08
申请号：AU1244001
申请日：2000-10-27
Applicant: COR THERAPEUTICS INC
Inventor： SCARBOROUGH ROBERT M JR , MEHROTA MUKUND , PANDEY ANJALI , SMYTH MARK
IPC: A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/551 , A61P7/02 , A61P9/00 , A61P9/10 , C07D401/04 , C07D413/14 , C07D471/10 , A61K31/438 , C07D209/00 , C07D221/00
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公开(公告)号：AU5283600A
公开(公告)日：2000-12-12
申请号：AU5283600
申请日：2000-05-24
Applicant: COR THERAPEUTICS INC
Inventor： ZHU BING-YAN , SCARBOROUGH ROBERT M JR
IPC: A61K31/155 , A61K31/18 , A61K31/275 , A61K31/401 , A61K31/402 , A61K31/451 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/10 , C07C311/46 , C07D207/16 , C07D211/60 , C07D241/04 , C07D243/08 , C07D401/04 , C07D403/04 , C07D413/04 , C07D207/00
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