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    METHOD FOR FERMENTATION PRODUCTION OF L-AMINO ACID
    1.
    发明专利
    METHOD FOR FERMENTATION PRODUCTION OF L-AMINO ACID 失效

    公开(公告)号：JP2000125893A

    公开(公告)日：2000-05-09

    申请号：JP30395299

    申请日：1999-10-26

    Applicant: DEGUSSA

    Inventor： BECKER ULRICH ,  PETER HEIDI DR ,  MORBACH SUSANNE DR ,  WALGER ILONA DR ,  KRAEMER REINHARD DR ,  PFEFFERLE WALTER DR

    IPC: C12P13/04 ,  C12N1/38 ,  C12P13/06 ,  C12P13/08 ,  C12R1/13 ,  C12R1/15

    Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound with controlling the influence of cell of high osmotic pressure by adding L-proline to a liquid medium containing a well-known C source and N-source at an early stage of fermentation and culturing a coryneform bacterium capable of producing and discharging an L-amino acid. SOLUTION: In this method for a fermentation production of an L-amino acid by culturing a coryneform bacterium (e.g. Corynebacterium glutamicum ATCC 13,032, etc.), capable of producing and discharging the L-amino acid, a fermentation liquid medium containing well-known C and N sources is mixed with L-proline in an amount of 0.01-10 g/L based on the fermentation liquid medium preferably at an early fermentation stage, the fermentation is performed in a minimum culture solution and/or in a limited culture solution to give the objective L-amino acid by a method for controlling the influence of cell of high osmotic pressure. L-Lysine, L-isoleucine, L-threonine, L-valine, etc., can be produced as the L-amino acid.

    ANIMAL FEED ADDITIVE AND ITS PRODUCTION
    2.
    发明专利
    ANIMAL FEED ADDITIVE AND ITS PRODUCTION 失效

    公开(公告)号：JP2000325024A

    公开(公告)日：2000-11-28

    申请号：JP2000132558

    申请日：2000-05-01

    Applicant: DEGUSSA

    Inventor： BINDER MICHAEL ,  UFFMANN KLAUS-ERICH ,  WALGER ILONA ,  BECKER ULRICH ,  PFEFFERLE WALTER ,  FRIEDRICH HEINZ

    IPC: A23K1/00 ,  A23K1/16 ,  A23K1/175 ,  C12P13/02

    Abstract: PROBLEM TO BE SOLVED: To profitably and efficiently obtain an animal feed additive having excellent flowability by adding an alkali (ne earth)metal hydroxide, or the like, to a fermentation broth containing D-pantothenic acid(salt) and then subjecting the mixture to a spray-drying treatment, or the like. SOLUTION: This animal feed additive is obtained by perfectly or partially separating a biomass and/or several other components from a fermentation broth containing D-pantothenic acid and/or one or more salts thereof selected from the group consisting of sodium, potassium, ammonium, magnesium and calcium salt thereof, adding an alkali (ne earth) metal hydroxide or oxide to the residual broth, and then (spray-)drying or (spray-)granulating the mixture to obtain the solid, particulate or granular easily flowable animal feed additive. The (hydr)oxide of the metal selected from the group consisting of the sodium, potassium, ammonium, magnesium and calcium compounds is preferably added in a stoichiometric ratio of 0.8 to 1.2 to the D-pantothenic acid.

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