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公开(公告)号:KR870000354B1
公开(公告)日:1987-03-05
申请号:KR840008498
申请日:1984-12-28
Applicant: DEGUSSA
Inventor: SCHEFFLER GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , NICKEL BERND , THIEMER KLAUS
IPC: C07D401/12 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/46 , A61K31/55 , A61P25/04 , A61P29/00 , C07D211/54 , C07D213/643 , C07D213/70 , C07D213/71 , C07D213/89 , C07D243/00 , C07D317/00 , C07D405/12 , C07D405/14 , C07D451/02 , C07D451/06 , C07D453/02
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公开(公告)号:FI84062B
公开(公告)日:1991-06-28
申请号:FI845126
申请日:1984-12-27
Applicant: DEGUSSA
Inventor: SCHEFFLER GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , NICKEL BERND , THIEMER KLAUS
IPC: C07D401/12 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/46 , A61K31/55 , A61P25/04 , A61P29/00 , C07D211/54 , C07D213/643 , C07D213/70 , C07D213/71 , C07D213/89 , C07D243/00 , C07D317/00 , C07D405/12 , C07D405/14 , C07D451/02 , C07D451/06 , C07D453/02
Abstract: There are disclosed pyridine-2-ethers and pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring corresponding to the formula I the pyridine-N-oxides and/or amine oxides thereof and the pharmaceutically acceptable salts thereof. The compounds show analgesic activity.
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公开(公告)号:HU191643B
公开(公告)日:1987-03-30
申请号:HU116884
申请日:1984-03-23
Applicant: DEGUSSA
Inventor: OEPEN GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , THIEMER KLAUS
IPC: C07D295/18 , A61K31/495 , A61K31/496 , A61P25/04 , A61P29/00 , C07D213/72 , C07D213/74 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/10 , C07D401/04 , C07D403/04 , A61K31/435
Abstract: There are prepared new pharmacologically active compounds of the formula: I In formula I R1 is a phenyl radical, pyridyl radical, a pyrimidyl group, or pyrazinyl radical, or a phenyl radical, pyridiyl radical, pyrimidyl radical, or pyrazinyl radical substituted by the radicals R3 and R4 which are the same or different and are hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, C1-C6-alkyl groups C1-C6-alkoxy groups, C3-C6-alkenyloxy groups, C3-C6-cycloalkyloxy groups, phenyl-C1-C4-alkoxy groups, C1-C6-alkylmercapto groups, the nitro group, the amino group, C1-C6-dialkylamino groups, C2-C6-alkanoyl groups, C2-C6-alkanoylamino groups, or C2-C6-alkanoyloxy groups and R2 is the adamantyl group, the 3,3-dimethyl-bicyclo[2.2.1]hept-2-yl radical, a saturated C3-C16-cycloalkenyl radical and alk is a straight or branched C1-C6 alkyl chain.
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4.
公开(公告)号:ZA848275B
公开(公告)日:1985-08-28
申请号:ZA848275
申请日:1984-10-23
Applicant: DEGUSSA
Inventor: SCHEFFLER GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , NICKEL BERND , THIEMER KLAUS
IPC: C07D401/12 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/46 , A61K31/55 , A61P25/04 , A61P29/00 , C07D211/54 , C07D213/643 , C07D213/70 , C07D213/71 , C07D213/89 , C07D243/00 , C07D317/00 , C07D405/12 , C07D405/14 , C07D451/02 , C07D451/06 , C07D453/02 , C07D , A61K
Abstract: There are disclosed pyridine-2-ethers and pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring corresponding to the formula I the pyridine-N-oxides and/or amine oxides thereof and the pharmaceutically acceptable salts thereof. The compounds show analgesic activity.
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公开(公告)号:AU3699684A
公开(公告)日:1985-07-04
申请号:AU3699684
申请日:1984-12-20
Applicant: DEGUSSA
Inventor: SCHEFFLER GERHARD , NICKEL BERND , THIEMER KLAUS , ENGEL JURGEN , JAKOVLEV VLADIMIR
IPC: C07D401/12 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/46 , A61K31/55 , A61P25/04 , A61P29/00 , C07D211/54 , C07D213/643 , C07D213/70 , C07D213/71 , C07D213/89 , C07D243/00 , C07D317/00 , C07D405/12 , C07D405/14 , C07D451/02 , C07D451/06 , C07D453/02
Abstract: There are disclosed pyridine-2-ethers and pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring corresponding to the formula I the pyridine-N-oxides and/or amine oxides thereof and the pharmaceutically acceptable salts thereof. The compounds show analgesic activity.
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公开(公告)号:NO845250A
公开(公告)日:1985-07-01
申请号:NO845250
申请日:1984-12-27
Applicant: DEGUSSA
Inventor: SCHEFFLER GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , NICKEL BERND , THIEMER KLAUS
IPC: C07D401/12 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/46 , A61K31/55 , A61P25/04 , A61P29/00 , C07D211/54 , C07D213/643 , C07D213/70 , C07D213/71 , C07D213/89 , C07D243/00 , C07D317/00 , C07D405/12 , C07D405/14 , C07D451/02 , C07D451/06 , C07D453/02 , C07D
CPC classification number: C07D213/70 , C07D211/54 , C07D213/89 , C07D401/12 , C07D405/14 , C07D451/06 , C07D453/02
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公开(公告)号:AU2605784A
公开(公告)日:1984-09-27
申请号:AU2605784
申请日:1984-03-23
Applicant: DEGUSSA
Inventor: OEPEN GERHARD , ENGEL JURGEN , JAKOVLEV VLADIMIR , THIEMER KLAUS
IPC: C07D295/18 , A61K31/495 , A61K31/496 , A61P25/04 , A61P29/00 , C07D213/72 , C07D213/74 , C07D239/42 , C07D241/20 , C07D295/185
Abstract: There are prepared new pharmacologically active compounds of the formula: I In formula I R1 is a phenyl radical, pyridyl radical, a pyrimidyl group, or pyrazinyl radical, or a phenyl radical, pyridiyl radical, pyrimidyl radical, or pyrazinyl radical substituted by the radicals R3 and R4 which are the same or different and are hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, C1-C6-alkyl groups C1-C6-alkoxy groups, C3-C6-alkenyloxy groups, C3-C6-cycloalkyloxy groups, phenyl-C1-C4-alkoxy groups, C1-C6-alkylmercapto groups, the nitro group, the amino group, C1-C6-dialkylamino groups, C2-C6-alkanoyl groups, C2-C6-alkanoylamino groups, or C2-C6-alkanoyloxy groups and R2 is the adamantyl group, the 3,3-dimethyl-bicyclo[2.2.1]hept-2-yl radical, a saturated C3-C16-cycloalkenyl radical and alk is a straight or branched C1-C6 alkyl chain.
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公开(公告)号:DK142084A
公开(公告)日:1984-09-26
申请号:DK142084
申请日:1984-02-29
Applicant: DEGUSSA
Inventor: OEPEN GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , THIEMER KLAUS
IPC: C07D295/18 , A61K31/495 , A61K31/496 , A61P25/04 , A61P29/00 , C07D213/72 , C07D213/74 , C07D239/42 , C07D241/20 , C07D295/185 , C07D
Abstract: There are prepared new pharmacologically active compounds of the formula: I In formula I R1 is a phenyl radical, pyridyl radical, a pyrimidyl group, or pyrazinyl radical, or a phenyl radical, pyridiyl radical, pyrimidyl radical, or pyrazinyl radical substituted by the radicals R3 and R4 which are the same or different and are hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, C1-C6-alkyl groups C1-C6-alkoxy groups, C3-C6-alkenyloxy groups, C3-C6-cycloalkyloxy groups, phenyl-C1-C4-alkoxy groups, C1-C6-alkylmercapto groups, the nitro group, the amino group, C1-C6-dialkylamino groups, C2-C6-alkanoyl groups, C2-C6-alkanoylamino groups, or C2-C6-alkanoyloxy groups and R2 is the adamantyl group, the 3,3-dimethyl-bicyclo[2.2.1]hept-2-yl radical, a saturated C3-C16-cycloalkenyl radical and alk is a straight or branched C1-C6 alkyl chain.
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公开(公告)号:DD213215A5
公开(公告)日:1984-09-05
申请号:DD26115284
申请日:1984-03-22
Applicant: DEGUSSA
Inventor: OEPEN GERHARD , ENGEL JUERGEN , JAKOVLEV VLADIMIR , THIEMER KLAUS
IPC: C07D295/18 , A61K31/495 , A61K31/496 , A61P25/04 , A61P29/00 , C07D213/72 , C07D213/74 , C07D239/42 , C07D241/20 , C07D295/185 , C07D241/04
Abstract: There are prepared new pharmacologically active compounds of the formula: I In formula I R1 is a phenyl radical, pyridyl radical, a pyrimidyl group, or pyrazinyl radical, or a phenyl radical, pyridiyl radical, pyrimidyl radical, or pyrazinyl radical substituted by the radicals R3 and R4 which are the same or different and are hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, C1-C6-alkyl groups C1-C6-alkoxy groups, C3-C6-alkenyloxy groups, C3-C6-cycloalkyloxy groups, phenyl-C1-C4-alkoxy groups, C1-C6-alkylmercapto groups, the nitro group, the amino group, C1-C6-dialkylamino groups, C2-C6-alkanoyl groups, C2-C6-alkanoylamino groups, or C2-C6-alkanoyloxy groups and R2 is the adamantyl group, the 3,3-dimethyl-bicyclo[2.2.1]hept-2-yl radical, a saturated C3-C16-cycloalkenyl radical and alk is a straight or branched C1-C6 alkyl chain.
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公开(公告)号:NO781159A
公开(公告)日:1978-10-05
申请号:NO781159
申请日:1978-04-03
Applicant: DEGUSSA
Inventor: KLEEMANN AXEL , JAKOVLEV VLADIMIR , THIEMER KLAUS , ENGEL JUERGEN
IPC: C07D295/08 , A61K31/495 , A61K31/496 , A61P25/18 , A61P25/20 , C07D213/74 , C07D213/80 , C07D295/033 , C07D295/088 , C07D295/092 , C07D295/135 , C07D303/24 , C07D307/68 , C07D333/38 , C07D
CPC classification number: C07D213/74 , C07D213/80 , C07D295/088 , C07D295/135 , C07D303/24
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