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公开(公告)号：WO9963972A9
公开(公告)日：2000-10-12
申请号：PCT/US9912772
申请日：1999-06-08
Applicant: DELSYS PHARMACEUTICAL CORP , CHEN JEN CHI , CHRAI SUGGY S , DESAI NITIN VITHALBHAI , HAMMER LAWRENCE HARRISON , KELLER DAVID , KUMAR NALIN , LAL PRINCE , LEVINE AARON WILLIAM , MURARI RAMASWAMY , MARA KERRY DENNIS O , POLINIAK EUGENE SAMUEL , RIVENBURG HOWARD CHRISTOPHER , ROACH WILLIAM RONALD , ROSATI DOMINIC STEPHEN , SINGH BAWA , SOUTHGATE PETER DAVID , SUN HOI CHEONG , ZANZUCCHI PETER JOHN
Inventor： CHEN JEN-CHI , CHRAI SUGGY S , DESAI NITIN VITHALBHAI , HAMMER LAWRENCE HARRISON , KELLER DAVID , KUMAR NALIN , LAL PRINCE , LEVINE AARON WILLIAM , MURARI RAMASWAMY , O'MARA KERRY DENNIS , POLINIAK EUGENE SAMUEL , RIVENBURG HOWARD CHRISTOPHER , ROACH WILLIAM RONALD , ROSATI DOMINIC STEPHEN , SINGH BAWA , SOUTHGATE PETER DAVID , SUN HOI CHEONG , ZANZUCCHI PETER JOHN
IPC: A61K9/14 , A61J1/03 , A61J3/00 , A61K9/16 , A61K9/51 , A61K9/70 , B05B5/025 , B05B5/08 , B05B5/16 , B65B1/04 , B65B1/30 , B65B11/50
CPC classification number: A61K9/70 , A61J1/035 , A61J3/00 , B05B5/08 , B65B1/04 , B65B1/30 , B65B11/50
Abstract: The present invention provides a product (1) that includes a pharmaceutical unit dosage or diagnostic form (6) that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate (8), a deposit (14) that is disposed on the substrate and a cover layer (9) that overlies the deposit and is joined to the substrate by a bond that encircles that deposit, thereby encapsulating it between the substrate and cover substrates. The deposit comprises a powder, at least some of which includes the at least one active ingredient. The unit form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.
Abstract translation: 本发明提供了一种产品（1），其包括药物单位剂量或诊断形式（6），其包含至少一种活性成分，其有效量不超过预定目标量的约5％ 。 在一个实施例中，单元形式包括衬底（8），设置在衬底上的沉积物（14）和覆盖在沉积物上的覆盖层（9），并且通过围绕该沉积物的键与衬底接合， 从而将其封装在基板和盖基板之间。 沉积物包含粉末，其中至少一些包括至少一种活性成分。 单元形式通过干粉沉积设备产生，其使用静电卡盘和带电粉末输送装置将粉末静电沉积在基底上。
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公开(公告)号：EP1210760A4
公开(公告)日：2003-05-21
申请号：EP00974094
申请日：2000-09-11
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： SUN HOI CHEONG , SINGH BAWA , RIVENBURG HOWARD CHRISTOPHER
CPC classification number: B82Y15/00 , B01J2219/00468 , B01J2219/005 , H02N1/004
Abstract: A charged particle (Bead) is moved from a first electrode (9) to a second electrode (10) also with the aid of a guide electrode (Guide Electrode).
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公开(公告)号：AU763869B2
公开(公告)日：2003-07-31
申请号：AU4675599
申请日：1999-06-08
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： CHEN JEN-CHI , CHRAI SUGGY S , DESAI NITIN VITHALBHAI , HAMMER LAWRENCE HARRISON , KELLER DAVID , KUMAR NALIN , LAL PRINCE , LEVINE AARON WILLIAM , MURARI RAMASWAMY , O'MARA KERRY DENNIS , POLINIAK EUGENE SAMUEL , RIVENBURG HOWARD CHRISTOPHER , ROACH WILLIAM RONALD , ROSATI DOMINIC STEPHEN , SINGH BAWA , SOUTHGATE PETER DAVID , SUN HOI CHEONG , ZANZUCCHI PETER JOHN
IPC: A61K9/14 , A61J1/03 , A61J3/00 , A61K9/16 , A61K9/51 , A61K9/70 , B05B5/025 , B05B5/08 , B05B5/16 , B65B1/04 , B65B1/30 , B65B11/50
Abstract: The present invention provides a product (1) that includes a pharmaceutical unit dosage or diagnostic form (6) that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate (8), a deposit (14) that is disposed on the substrate and a cover layer (9) that overlies the deposit and is joined to the substrate by a bond that encircles that deposit, thereby encapsulating it between the substrate and cover substrates. The deposit comprises a powder, at least some of which includes the at least one active ingredient. The unit form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.
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4.发明公开INHALER APPARATUS WITH AN ELECTRONIC MEANS FOR ENHANCED RELEASE OF DRY POWDERS 失效随着电子INHALER手段干粉改进的通讯
公开(公告)号：EP0917475A4
公开(公告)日：2000-08-30
申请号：EP97927871
申请日：1997-06-10
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： SUN HOI CHEONG STEVE , SINGH BAWA , RIVENBURG HOWARD CHRISTOPHER , DATTA PABITRA
CPC classification number: A61M15/0045 , A61M15/0051 , A61M15/0055 , A61M2205/0233
Abstract: The device is directed to an inhaler with a substrate (101) having a medicament (107) deposited thereon. The device further contains a conductive layer (100) and a dielectric layer (103).
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5.发明公开INHALER APPARATUS WITH MODIFIED SURFACES FOR ENHANCED RELEASE OF DRY POWDERS 失效随着对干粉改进的通讯改性表面INHALER
公开(公告)号：EP0917476A4
公开(公告)日：2000-08-16
申请号：EP97929947
申请日：1997-06-10
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： DATTA PABITRA , RIVENBURG HOWARD CHRISTOPHER , DESAI NITIN
CPC classification number: A61M15/0045 , A61M2205/0233
Abstract: This invention is an inhaler providing surface topology (202, 204) for minimizing the area of contact between the medicament (107) and the surfaces of the inhaler. The surfaces are preferably made of a material having a low surface energy, and more preferably, also having, when uncharged, no substantial van der Waals or electrostatic interaction with the medicament. Furthermore, the material is preferably substantially chemically unreactive with the medicament.
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Patent Agency Ranking
公开(公告)号：AU1251701A
公开(公告)日：2001-04-10
申请号：AU1251701
申请日：2000-09-11
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： SUN HOI CHEONG , SINGH BAWA , RIVENBURG HOWARD CHRISTOPHER
Abstract: Provided is a method of moving a charged particle from a first position at which it is retained by a first electrode to a second position at which it is retained by a second electrode, the method comprising: applying a potential to the second electrode to attract the particle; and applying a potential to a guide electrode offset from the particle at the first position, wherein the applied potential is effective to reduce the attraction of the particle to the first position sufficiently to allow the potential applied at the second electrode to be effective to move the particle from the first position to the second position.
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公开(公告)号：NZ332962A
公开(公告)日：2000-08-25
申请号：NZ33296297
申请日：1997-06-10
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： DATTA PABITRA , RIVENBURG HOWARD CHRISTOPHER , DESAI NITIN
Abstract: The inhaler apparatus comprises interior surfaces having contact with medicament particles of a selected size range for inhalation. The interior surfaces include an interior surface of a mouthpiece and a substrate with medicament particles deposited thereon. At least one such interior surfaces is textured having indentations or raised areas defining valleys of dimension and spacings selected to decrease the area of contact between medicament particles of a selected size range and the textured surface to reduce the adherence of the medicament particles to the textured surfaces.
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公开(公告)号：AT277657T
公开(公告)日：2004-10-15
申请号：AT97929947
申请日：1997-06-10
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： DATTA PABITRA , RIVENBURG HOWARD CHRISTOPHER , DESAI NITIN
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公开(公告)号：AU4675599A
公开(公告)日：1999-12-30
申请号：AU4675599
申请日：1999-06-08
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： CHEN JEN-CHI , CHRAI SUGGY S , DESAI NITIN VITHALBHAI , HAMMER LAWRENCE HARRISON , KELLER DAVID , KUMAR NALIN , LAL PRINCE , LEVINE AARON WILLIAM , MURARI RAMASWAMY , O'MARA KERRY DENNIS , POLINIAK EUGENE SAMUEL , RIVENBURG HOWARD CHRISTOPHER , ROACH WILLIAM RONALD , ROSATI DOMINIC STEPHEN , SINGH BAWA , SOUTHGATE PETER DAVID , SUN HOI CHEONG , ZANZUCCHI PETER JOHN
IPC: A61K9/14 , A61J1/03 , A61J3/00 , A61K9/16 , A61K9/51 , A61K9/70 , B05B5/025 , B05B5/08 , B05B5/16 , B65B1/04 , B65B1/30 , B65B11/50
Abstract: The present invention provides a product (1) that includes a pharmaceutical unit dosage or diagnostic form (6) that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate (8), a deposit (14) that is disposed on the substrate and a cover layer (9) that overlies the deposit and is joined to the substrate by a bond that encircles that deposit, thereby encapsulating it between the substrate and cover substrates. The deposit comprises a powder, at least some of which includes the at least one active ingredient. The unit form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.
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公开(公告)号：CA2333107A1
公开(公告)日：1999-12-16
申请号：CA2333107
申请日：1999-06-08
Applicant: DELSYS PHARMACEUTICAL CORP
Inventor： POLINIAK EUGENE SAMUEL , SINGH BAWA , RIVENBURG HOWARD CHRISTOPHER , SOUTHGATE PETER DAVID , SUN HOI CHEONG , ZANZUCCHI PETER JOHN , KUMAR NALIN , CHRAI SUGGY S , ROACH WILLIAM RONALD , DESAI NITIN VITHALBHAI , HAMMER LAWRENCE HARRISON , KELLER DAVID , CHEN JEN-CHI , O'MARA KERRY DENNIS , MURARI RAMASWAMY , LAL PRINCE , ROSATI DOMINIC STEPHEN , LEVINE AARON WILLIAM
IPC: A61K9/14 , A61J1/03 , A61J3/00 , A61K9/16 , A61K9/51 , A61K9/70 , B05B5/025 , B05B5/08 , B05B5/16 , B65B1/04 , B65B1/30 , B65B11/50
Abstract: The present invention provides a product (1) that includes a pharmaceutical unit dosage or diagnostic form (6) that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate (8), a deposit (14) that is disposed on the substrate and a cover layer (9) that overlies the deposit an d is joined to the substrate by a bond that encircles that deposit, thereby encapsulating it between the substrate and cover substrates. The deposit comprises a powder, at least some of which includes the at least one active ingredient. The unit form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.
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