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公开(公告)号：WO2011142836A9
公开(公告)日：2012-01-05
申请号：PCT/US2011000887
申请日：2011-05-16
Applicant: FLUIDIGM CORP , JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , PIEPRZYK MARTIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
Inventor： JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , PIEPRZYK MARTIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
CPC classification number: C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , G01N33/542 , G01N33/582 , G01N33/6893 , G01N2800/368 , C12Q2521/301 , C12Q2521/501 , C12Q2525/155 , C12Q2535/131 , C12Q2537/143 , C12Q2537/16 , C12Q2563/173
Abstract: The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample.
Abstract translation: 本发明提供了用于检测基因型，突变和/或非整倍性的基于扩增的方法。 这些方法具有广泛的适用性，但特别适合于检测和定量存在于母体液样品中的游离胎儿DNA中的靶核酸。
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公开(公告)号：WO2011142836A3
公开(公告)日：2012-07-05
申请号：PCT/US2011000887
申请日：2011-05-16
Applicant: FLUIDIGM CORP , JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , PIEPRZYK MARTIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
Inventor： JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , PIEPRZYK MARTIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
CPC classification number: C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , G01N33/542 , G01N33/582 , G01N33/6893 , G01N2800/368 , C12Q2521/301 , C12Q2521/501 , C12Q2525/155 , C12Q2535/131 , C12Q2537/143 , C12Q2537/16 , C12Q2563/173
Abstract: The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample.
Abstract translation: 本发明提供用于检测基因型，突变和/或非整倍体的基于扩增的方法。 这些方法具有广泛的适用性，但是特别适合于检测和定量存在于母体体液样品中的游离胎儿DNA中的靶核酸。
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公开(公告)号：SG185543A1
公开(公告)日：2012-12-28
申请号：SG2012083424
申请日：2011-05-16
Applicant: FLUIDIGM CORP , PIEPRZYK MARTIN
Inventor： JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , PIEPRZYK MARTIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
Abstract: The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample.
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公开(公告)号：EP2569447A4
公开(公告)日：2013-11-27
申请号：EP11780930
申请日：2011-05-16
Applicant: FLUIDIGM CORP , PIEPRZYK MARTIN
Inventor： PIEPRZYK MARTIN , JONES ROBERT C , LIVAK KENNETH J , MAY ANDREW , MIR ALAIN , QIN JIAN , RAMAKRISHNAN RAMESH , SPURGEON SANDRA , WANG JUN , ZIMMERMANN BERNHARD G
CPC classification number: C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , G01N33/542 , G01N33/582 , G01N33/6893 , G01N2800/368 , C12Q2521/301 , C12Q2521/501 , C12Q2525/155 , C12Q2535/131 , C12Q2537/143 , C12Q2537/16 , C12Q2563/173
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