中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

4 records (took 0.027 seconds)

    ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME
    1.
    发明申请
    ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME 审中-公开

    公开(公告)号：WO2020068900A1

    公开(公告)日：2020-04-02

    申请号：PCT/US2019/052829

    申请日：2019-09-25

    Applicant: GENOMATICA, INC.

    Inventor： SHAH, Amit ,  WARNER, Joseph

    IPC: C12N9/02

    Abstract: The invention provides polypeptides and encoding nucleic acids of aldehyde dehydrogenase variants. The invention also provides cells expressing aldehyde dehydrogenase variants. The invention further provides methods for producing 3-hydroxybutyraldehyde (3-HBal) and/or 1,3-butanediol (1,3-BDO), or an ester or amide thereof, comprising culturing cells expressing an aldehyde dehydrogenase variant or using lysates of such cells. The invention additional provides methods for producing 4-hydroxybutyraldehyde (4-HBal) and/or 1,4-butanediol (1,4-BDO), or an ester or amide thereof, comprising culturing cells expressing an aldehyde dehydrogenase variant or using lysates of such cells.

    ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE
    2.
    发明申请
    ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE 审中-公开

    公开(公告)号：WO2018183664A1

    公开(公告)日：2018-10-04

    申请号：PCT/US2018/025122

    申请日：2018-03-29

    Applicant: GENOMATICA, INC.

    Inventor： HOFF, Kevin ,  TRACEWELL, Cara, Ann ,  CHAN, Kui ,  SHAH, Amit ,  WARNER, Joseph ,  NOBLE, Michael

    IPC: C12N9/02

    Abstract: The invention provides polypeptides and encoding nucleic acids of aldehyde dehydrogenase variants. The invention also provides cells expressing aldehyde dehydrogenase variants. The invention further provides methods for producing 3-hydroxybutyraldehyde (3-HBal) and/or 1,3 -butanediol (1,3-BDO), or an ester or amide thereof, comprising culturing cells expressing an aldehyde dehydrogenase variant or using lysates of such cells. The invention additional provides methods for producing 4-hydroxybutyraldehyde (4-HBal) and/or 1,4-butanediol (1,4-BDO), or an ester or amide thereof, comprising culturing cells expressing an aldehyde dehydrogenase variant or using lysates of such cells.

Patent Agency Ranking