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    TEMPERATURE-CONTROLLING MICROFLUIDIC DEVICES
    1.
    发明申请
    TEMPERATURE-CONTROLLING MICROFLUIDIC DEVICES 审中-公开

    公开(公告)号：WO2019103730A1

    公开(公告)日：2019-05-31

    申请号：PCT/US2017/062935

    申请日：2017-11-22

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： HIGGINS, Adam ,  GOVYADINOV, Alexander

    IPC: F28F27/00 ,  B81B3/00 ,  C12M1/02 ,  B01L3/00 ,  G05D23/20

    Abstract: The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a driver chip and a fluid chamber located over the driver chip. First and second microfluidic loops can have fluid driving ends and fluid outlet ends connected to the fluid chamber. The first and second microfluidic loops can include a portion thereof located outside a boundary of the driver chip. A first fluid actuator can be on the driver chip associated with the fluid driving end of the first microfluidic loop to circulate fluid through the first microfluidic loop. A second fluid actuator can be on the driver chip associated with the fluid driving end of the second microfluidic loop to circulate fluid through the second microfluidic loop.

    MULTIZONAL MICROFLUIDIC DEVICES
    3.
    发明申请
    MULTIZONAL MICROFLUIDIC DEVICES 审中-公开

    公开(公告)号：WO2019103732A1

    公开(公告)日：2019-05-31

    申请号：PCT/US2017/062943

    申请日：2017-11-22

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： TORNIAINEN, Erik D. ,  ELY, Hilary ,  CUMBIE, Michael W. ,  WHITE, Rachel M. ,  HIGGINS, Adam

    IPC: B01L3/00

    Abstract: A multizonal microfluidic device can include a substrate with multiple structures mounted thereon, including a first and second lid, and a first and second microchip. The first lid and the substrate can form a first microfluidic chamber between structures including a first interior surface of the first lid and a first discrete portion of the substrate. The first lid can include a first inlet and a first vent positioned relative to one another to facilitate loading of fluid to the first microfluidic chamber via capillary action. A portion of the first microchip can be positioned within the first microfluidic chamber. Furthermore, the second lid can be configured like the first lid and can also be mounted on the substrate forming a second microfluidic chamber with the second microchip positioned within the second microfluidic chamber.

    MICROFLUIDIC DEVICES
    8.
    发明申请
    MICROFLUIDIC DEVICES 审中-公开

    公开(公告)号：WO2018186880A1

    公开(公告)日：2018-10-11

    申请号：PCT/US2017/026551

    申请日：2017-04-07

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： GOVYADINOV, Alexander ,  HIGGINS, Adam ,  KORNILOVICH, Pavel

    IPC: C12Q1/68 ,  C12M3/00 ,  B81B1/00 ,  B01L3/00

    Abstract: The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a microfluidic channel. A vent chamber can be in fluid communication with the microfluidic channel. A capillary break can be located between the microfluidic channel and the vent chamber. The capillary break can include a tapered portion and a narrowed opening with a smaller width than a width of the microfluidic channel. A vent port can vent gas from the vent chamber. The vent port can be located a distance away from the capillary break so that a fluid in the capillary break does not escape through the vent port.

    TEMPERATURE-CYCLING MICROFLUIDIC DEVICES
    9.
    发明申请
    TEMPERATURE-CYCLING MICROFLUIDIC DEVICES 审中-公开

    公开(公告)号：WO2019103744A1

    公开(公告)日：2019-05-31

    申请号：PCT/US2017/063107

    申请日：2017-11-22

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： HIGGINS, Adam ,  GOVYADINOV, Alexander ,  CUMBIE, Michael W.

    IPC: B01L7/00 ,  B01L3/00 ,  C12Q1/68

    Abstract: The present disclosure is drawn to temperature-cycling microfluidic devices. In one example, a temperature-cycling microfluidic device can include a driver chip having a top surface and a heat exchange substrate having a top surface coplanar with the top surface of the driver chip. A fluid chamber can be located on the top surface of the driver chip. A first and second microfluidic loop can have fluid driving ends and fluid outlet ends connected to the fluid chamber and can include portions thereof located on the top surface of the heat exchange substrate. A first and second fluid actuator can be on the driver chip. The first and second fluid actuators can be associated with the fluid driving ends of the first and second microfluidic loops, respectively, to circulate fluid through the first and second microfluidic loops.

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