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公开(公告)号:WO2019103732A1
公开(公告)日:2019-05-31
申请号:PCT/US2017/062943
申请日:2017-11-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: TORNIAINEN, Erik D. , ELY, Hilary , CUMBIE, Michael W. , WHITE, Rachel M. , HIGGINS, Adam
IPC: B01L3/00
Abstract: A multizonal microfluidic device can include a substrate with multiple structures mounted thereon, including a first and second lid, and a first and second microchip. The first lid and the substrate can form a first microfluidic chamber between structures including a first interior surface of the first lid and a first discrete portion of the substrate. The first lid can include a first inlet and a first vent positioned relative to one another to facilitate loading of fluid to the first microfluidic chamber via capillary action. A portion of the first microchip can be positioned within the first microfluidic chamber. Furthermore, the second lid can be configured like the first lid and can also be mounted on the substrate forming a second microfluidic chamber with the second microchip positioned within the second microfluidic chamber.
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公开(公告)号:WO2018186881A1
公开(公告)日:2018-10-11
申请号:PCT/US2017/026562
申请日:2017-04-07
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: TORNIAINEN, Erik D. , GOVYADINOV, Alexander , KORNILOVICH, Pavel , MARKEL, David P.
Abstract: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.
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公开(公告)号:WO2018075069A1
公开(公告)日:2018-04-26
申请号:PCT/US2016/058235
申请日:2016-10-21
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: TORNIAINEN, Erik D. , GOVYADINOV, Alexander N. , KORNILOVICH, Pavel , MARKEL, David P. , SEAVER, Richard W.
Abstract: An immiscible droplet generation system may include a chip, a microfluidic channel integrated into the chip, an input to the microfluidic channel through which the microfluidic channel is to be filled with a first fluid that is to be moved through the microfluidic channel and a droplet generator. The droplet generator is integrated into the chip to generate a droplet of a second fluid, immiscible within the first fluid, and to inject the droplet into the first fluid in the microfluidic channel.
Abstract translation: 不可混溶的液滴生成系统可以包括芯片,集成到芯片中的微流体通道,微流体通道的输入,微流体通道将被填充待移动的第一流体 通过微流体通道和液滴发生器。 将液滴发生器集成到芯片中以产生第二流体的液滴,第二流体在第一流体内不混溶,并将液滴注入微流体通道中的第一流体中。 p>
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公开(公告)号:WO2017119902A1
公开(公告)日:2017-07-13
申请号:PCT/US2016/012699
申请日:2016-01-08
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: TORNIAINEN, Erik D. , GOVYADINOV, Alexander , KORNILOVICH, Pavel , MARKEL, David P.
CPC classification number: B01L3/50273 , B01L7/52 , B01L2300/0864 , B01L2300/087 , B01L2300/1827 , B01L2400/0442 , C12M23/16 , C12M41/12
Abstract: Examples include polymerase chain reaction (PCR) devices. Example PCR devices comprise a fluid input, a fluid output, and a set of microfluidic channels that fluidly connect the fluid input and the fluid output. Each microfluidic channel comprises a reaction chamber, and examples further comprise at least one heating element, where the at least one heating element is positioned in the reaction chamber of each microfluidic channel. The at least one heating element is to heat fluid in the reaction chamber of each fluid channel, and the at least one heating element is to pump fluid to the reaction chamber and from the reaction chamber of each microfluidic channel.
Abstract translation: 例子包括聚合酶链式反应(PCR)装置。 示例PCR装置包括流体输入,流体输出和流体连接流体输入和流体输出的一组微流体通道。 每个微流体通道包括反应室,并且实例还包括至少一个加热元件,其中至少一个加热元件位于每个微流体通道的反应室中。 所述至少一个加热元件用于加热每个流体通道的反应室中的流体,并且所述至少一个加热元件用于将流体泵送到每个微流体通道的反应室和反应室。 p>
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公开(公告)号:WO2016175865A1
公开(公告)日:2016-11-03
申请号:PCT/US2015/028665
申请日:2015-04-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: GOVYADINOV, Alexander , YAMASHITA, Tsuyoshi , TORNIAINEN, Erik D.
CPC classification number: B41J2/18 , B41J2/1404 , B41J2/14056 , B41J2/14153 , B41J2/175 , B41J2002/14354 , B41J2002/14403 , B41J2002/14467 , B41J2202/12
Abstract: A fluid ejection device includes a fluid slot, a first fluid ejection chamber communicated with the fluid slot and including a first drop ejecting element, a second fluid ejection chamber including a second drop ejecting element, and a fluid circulation path including a first portion communicated with the fluid slot and the second fluid ejection chamber, and a second portion communicated with the first fluid ejection chamber and the second fluid ejection chamber, with the fluid circulation path including a fluid circulating element within the first portion.
Abstract translation: 流体喷射装置包括流体槽,与流体槽连通并包括第一液滴喷射元件的第一流体喷射室,包括第二液滴喷射元件的第二流体喷射室,以及包括与 流体槽和第二流体喷射室,以及与第一流体喷射室和第二流体喷射室连通的第二部分,其中流体循环路径在第一部分内包括流体循环元件。
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公开(公告)号:WO2012106307A2
公开(公告)日:2012-08-09
申请号:PCT/US2012/023272
申请日:2012-01-31
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , WHITE, Lawrence H. , MARDILOVICH, Peter , TORNIAINEN, Erik D. , FEINN, James A. , STRAND, Thomas R. , CRUZ-URIBE, Tony S.
Inventor: WHITE, Lawrence H. , MARDILOVICH, Peter , TORNIAINEN, Erik D. , FEINN, James A. , STRAND, Thomas R. , CRUZ-URIBE, Tony S.
CPC classification number: B41J2/1412 , B41J2/14129
Abstract: A fluid ejection device includes a firing chamber having an ejection orifice opposite a chamber floor, a heating element and a mesa projecting from the chamber floor, the mesa is spaced from the heating element to define a passive zone between the mesa and heating element.
Abstract translation: 流体喷射装置包括具有与腔室底板相对的喷射孔的喷射室,加热元件和从室底板突出的台面,台面与加热元件间隔开以限定台面和加热元件之间的被动区域。
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公开(公告)号:WO2022191821A1
公开(公告)日:2022-09-15
申请号:PCT/US2021/021437
申请日:2021-03-09
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: GOVYADINOV, Alexander N. , CUMBIE, Michael W. , OLBRICH, Craig A. , TORNIAINEN, Erik D. , GILA, Omer
Abstract: In some examples, a fluid dispensing device includes a fluid chamber, a heating element adjacent the fluid chamber, and an orifice adjacent the fluid chamber. A ratio of an area of a surface of the heating element to an orifice area of the orifice is greater than or equal to 3, where the surface of the heating element faces the fluid chamber.
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公开(公告)号:WO2022159097A1
公开(公告)日:2022-07-28
申请号:PCT/US2021/014591
申请日:2021-01-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: DENISON, Carson , TORNIAINEN, Erik D. , SEAVER, Richard W. , KORNILOVICH, Pavel , GOVYADINOV, Alexander , JEBAKUMAR, Anand Samuel
Abstract: A microfluidic device includes a chamber having sidewalls, a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has an orientation relative to the inlet defined by a leading surface and a trailing corner opposite the leading corner. The trailing corner has an angle less than a threshold angle that is based on a fluidic contact angle. The orientations of the pillars relative to the inlet promote fluid flow from the inlet throughout the chamber without trapping gas at the sidewalls of the chamber.
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公开(公告)号:WO2019190488A1
公开(公告)日:2019-10-03
申请号:PCT/US2018/024665
申请日:2018-03-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: SHKOLNIKOV, Viktor , GOVYADINOV, Alexander , KORNILOVICH, Pavel , TORNIAINEN, Erik D.
Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a separation chamber, at least two output channels, and an integrated pump to facilitate flow through the separation chamber. The separation chamber is in fluid communication with the second end of the input channel. The separation chamber has a passive separation structure, the passive separation structure including an array of columns spaced apart to facilitate separation of particles in a flow based on a size of the particles. Each output channel is in fluid communication with the separation chamber to receive separated particles. The integrated pump is positioned within at least one of the input channel or one of the at least two output channels.
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公开(公告)号:WO2019103729A1
公开(公告)日:2019-05-31
申请号:PCT/US2017/062925
申请日:2017-11-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: ELY, Hilary , HIGGINS, Adam , WHITE, Rachel M. , TORNIAINEN, Erik D. , WOODFORD, Tod , CUMBIE, Michael W. , CHEN, Chien-Hua
Abstract: The present disclosure is drawn to microfluidic devices. A microfluidic device can include a substrate, a lid mounted to the substrate, and a microchip mounted to the substrate. The lid mounted to the substrate can form a discrete microfluidic chamber between structures including an interior surface of the lid and a portion of the substrate. The lid can include an inlet and a vent positioned relative to one another to facilitate loading of fluid to the discrete microfluidic chamber via capillary action. A portion of the microchip can be positioned within the discrete microfluidic chamber.
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