公开(公告)号：HU203117B

公开(公告)日：1991-05-28

申请号：HU130887

申请日：1987-03-25

Applicant: HOECHST AG

Inventor： HENNING RAINER ,  HOCK FRANZ ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUEGER WOLFGANG ,  SCHOLTHOLT JOSEF ,  URBACH HANSJOERG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  A61K37/02

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：FI891891A

公开(公告)日：1989-10-23

申请号：FI891891

申请日：1989-04-20

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJOERG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUEGER WOLFGANG

IPC: A61K38/00 ,  C07C219/02 ,  A61P25/28 ,  C07K1/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K

Abstract: The invention relates to esters of amino acids, of the formula I in which n is 2 and R, R , R , R , R and R have the meaning indicated in the description, to a process and intermediates for the preparation thereof, to agents containing them and to the use thereof.

公开(公告)号：NO178546B

公开(公告)日：1996-01-08

申请号：NO871282

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJORG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUGER WOLFGANG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：DD280765A5

公开(公告)日：1990-07-18

申请号：DD30111887

申请日：1987-03-25

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJOERG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUEGER WOLFGANG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K1/10 ,  A61K37/02

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：PT84564B

公开(公告)日：1989-11-10

申请号：PT8456487

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： HENNING RAINER ,  NICKEL WOLF-ULRICH ,  HOCK FRANZ ,  LERCH ULRICH ,  URBACH HANSJORG ,  RUGER WOLFGANG ,  SCHOLTHOLT JOSEF

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  A61K37/02 ,  A61K37/64

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：FI891891A0

公开(公告)日：1989-04-20

申请号：FI891891

申请日：1989-04-20

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJOERG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUEGER WOLFGANG

IPC: A61K38/00 ,  C07C219/02 ,  A61P25/28 ,  C07K1/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K

Abstract: The invention relates to esters of amino acids, of the formula I in which n is 2 and R, R , R , R , R and R have the meaning indicated in the description, to a process and intermediates for the preparation thereof, to agents containing them and to the use thereof.

公开(公告)号：NO871282L

公开(公告)日：1987-09-28

申请号：NO871282

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJORG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUGER WOLFGANG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K5/00

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：NO871282A

公开(公告)日：1987-09-28

申请号：NO871282

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJORG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUGER WOLFGANG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K5/00

CPC classification number: C07K5/0222 ,  A61K38/00

公开(公告)号：PT84564A

公开(公告)日：1987-04-01

申请号：PT8456487

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： HOCK FRANZ ,  SCHOLTHOLT JOSEF ,  URBACH HANSJOERG ,  HENNING RAINER ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUEGER WOLFGANG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07C103/00 ,  A61K31/16

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：CA1341064C

公开(公告)日：2000-08-01

申请号：CA533092

申请日：1987-03-26

Applicant: HOECHST AG

Inventor： SCHOLTHOLT JOSEF ,  HOCK FRANZ ,  LERCH ULRICH ,  NICKEL WOLF-ULRICH ,  RUGER WOLFGANG ,  HENNING RAINER ,  URBACH HANSJORG

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  A61K31/40

Abstract: Compounds having a coginition adjuvant action, agents containing them and the use thereof in the treatment and prophylaxis of cognitive dysfunctions The invention relates to new compounds having a cognition adjuvant action, to the use of ACE inhibitors as medicaments having a cognition adjuvant action, to agents containing them, and to the use thereof for the treatment and prophylaxis of cognitive dysfunctions.