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1.发明专利
公开(公告)号：ZA9109605B
公开(公告)日：1992-08-26
申请号：ZA9109605
申请日：1991-12-05
Applicant: HOECHST AG
Inventor： KRAMER WERNER , WERNER KRAMER , WESS GUENTHER , GUENTHER WESS , MUELLNER STEFAN , STEFAN MUELLNER , NEUBAUER HORST , HORST NEUBAUER
CPC classification number: C07J43/003 , C07J9/005 , C07J31/006 , C07J41/0016 , C07J41/0055 , C07J41/0061 , C07J41/0094
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公开(公告)号：ZA9206232B
公开(公告)日：1993-04-28
申请号：ZA9206232
申请日：1992-08-19
Applicant: HOECHST AG
Inventor： MUELLER GUENTER , GUENTER MUELLER , TRIPIER DOMINIQUE , DOMINIQUE TRIPIER , MUELLNER STEFAN , STEFAN MUELLNER
IPC: A61K38/28 , A61K31/715 , A61K38/00 , A61P3/08 , A61P3/10 , C07K1/22 , C07K5/08 , C07K5/093 , C07K5/10 , C07K9/00 , C07K14/37 , C07K14/41 , C07K14/475 , C07K14/575 , C07K14/62 , C07K14/65 , C12P19/26 , C12P21/00 , C12P21/02 , C12R1/865 , C07K
CPC classification number: C07K14/475 , A61K38/00 , C07K5/0827 , C07K5/1027 , C07K9/001 , C12P19/26
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Patent Agency Ranking
公开(公告)号：ZA9007569B
公开(公告)日：1991-08-28
申请号：ZA9007569
申请日：1990-09-21
Applicant: HOECHST AG
Inventor： MUELLNER STEFAN , STEFAN MUELLNER
CPC classification number: C07K16/26
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公开(公告)号：ZA926232B
公开(公告)日：1993-04-28
申请号：ZA926232
申请日：1992-08-19
Applicant: HOECHST AG
Inventor： MUELLER GUENTER , GUENTER MUELLER , TRIPIER DOMINIQUE , DOMINIQUE TRIPIER , MUELLNER STEFAN , STEFAN MUELLNER
IPC: A61K38/28 , A61K31/715 , A61K38/00 , A61P3/08 , A61P3/10 , C07K1/22 , C07K5/08 , C07K5/093 , C07K5/10 , C07K9/00 , C07K14/37 , C07K14/41 , C07K14/475 , C07K14/575 , C07K14/62 , C07K14/65 , C12P19/26 , C12P21/00 , C12P21/02 , C12R1/865 , C07K
Abstract: Phosphoinositolglycan peptides, obtainable by cleavage of adenosine-3%,5%-cyclic monophosphate binding protein, which contain glucosamine, galactose, mannose, inositol, phosphoric acid, ethanolamine and a peptide containing the sequence Asn-Cys-Tyr, their preparation and use for the treatment of diabetes mellitus and non-insulin-dependent diabetes are described.
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公开(公告)号：HRP940751B1
公开(公告)日：2000-12-31
申请号：HRP940751
申请日：1994-10-25
Applicant: HOECHST AG
Inventor： WERNER KRAMER , GUENTHER WESS , STEFAN MUELLNER , HORST NEUBAUER
Abstract: The invention relates to bile acid derivatives of the formula I G1-X-G2(I) in which G1 and G2 are bile acid radicals or modified bile acid radicals in the form of the free acids, the esters or amides, the salt forms and also the forms derivatized on the alcohol groups and X is a bridge group or a single covalent bond, it being possible for G1 and G2 to be optionally bonded via X. The compounds according to the invention have a high affinity for the specific bile acid transport system of the small intestine and inhibit bile acid absorption in a concentration-dependent and competitive manner.
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6.发明专利
公开(公告)号：ZA919605B
公开(公告)日：1992-08-26
申请号：ZA919605
申请日：1991-12-05
Applicant: HOECHST AG
Inventor： KRAMER WERNER , WERNER KRAMER , WESS GUENTHER , GUENTHER WESS , MUELLNER STEFAN , STEFAN MUELLNER , NEUBAUER HORST , HORST NEUBAUER
Abstract: The invention relates to bile acid derivatives of the formula I G1-X-G2(I) in which G1 and G2 are bile acid radicals or modified bile acid radicals in the form of the free acids, the esters or amides, the salt forms and also the forms derivatized on the alcohol groups and X is a bridge group or a single covalent bond, it being possible for G1 and G2 to be optionally bonded via X. The compounds according to the invention have a high affinity for the specific bile acid transport system of the small intestine and inhibit bile acid absorption in a concentration-dependent and competitive manner.
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公开(公告)号：ZA907569B
公开(公告)日：1991-08-28
申请号：ZA907569
申请日：1990-09-21
Applicant: HOECHST AG
Inventor： MUELLNER STEFAN , STEFAN MUELLNER
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