公开(公告)号：ZA919938B

公开(公告)日：1992-09-30

申请号：ZA919938

申请日：1991-12-18

Applicant: HOECHST AG

Inventor： MULLNER STEFAN ,  STEFAN MULLNER ,  KOENIG WOLFGANG ,  WOLFGANG KOENIG ,  MUELLER GUENTER ,  GUENTER MUELLER

IPC: A61K38/00 ,  A61K38/06 ,  A61K38/08 ,  A61K38/28 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07K1/113 ,  C07K5/08 ,  C07K5/087 ,  C07K5/10 ,  C07K7/00 ,  C07K7/06 ,  C07K14/62 ,  C07K ,  A61K

Abstract: Short peptides of the formula I X-Y-A-B-C-Cys-D-E (I> in which A and B are an amino acid or a covalent bond, C and D are an amino acid or a substituted amino acid, E is a modified or unmodified amino acid or a covalent bond, X is a radical or hydrogen and Y is leucine or a covalent bond, or dimers of the peptides of the formula I with cystine as dimerisation component, the stereoisomeric forms thereof where appropriate or their physiologically tolerated salts, the preparation thereof, and their use for the treatment of diabetes mellitus are described.

公开(公告)号：ZA9109938B

公开(公告)日：1992-09-30

申请号：ZA9109938

申请日：1991-12-18

Applicant: HOECHST AG

Inventor： MULLNER STEFAN ,  STEFAN MULLNER ,  KOENIG WOLFGANG ,  WOLFGANG KOENIG ,  MUELLER GUENTER ,  GUENTER MUELLER

IPC: A61K38/00 ,  A61K38/06 ,  A61K38/08 ,  A61K38/28 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07K1/113 ,  C07K5/08 ,  C07K5/087 ,  C07K5/10 ,  C07K7/00 ,  C07K7/06 ,  C07K14/62 ,  C07K ,  A61K

CPC classification number: C07K14/62 ,  A61K38/00

公开(公告)号：ZA926232B

公开(公告)日：1993-04-28

申请号：ZA926232

申请日：1992-08-19

Applicant: HOECHST AG

Inventor： MUELLER GUENTER ,  GUENTER MUELLER ,  TRIPIER DOMINIQUE ,  DOMINIQUE TRIPIER ,  MUELLNER STEFAN ,  STEFAN MUELLNER

IPC: A61K38/28 ,  A61K31/715 ,  A61K38/00 ,  A61P3/08 ,  A61P3/10 ,  C07K1/22 ,  C07K5/08 ,  C07K5/093 ,  C07K5/10 ,  C07K9/00 ,  C07K14/37 ,  C07K14/41 ,  C07K14/475 ,  C07K14/575 ,  C07K14/62 ,  C07K14/65 ,  C12P19/26 ,  C12P21/00 ,  C12P21/02 ,  C12R1/865 ,  C07K

Abstract: Phosphoinositolglycan peptides, obtainable by cleavage of adenosine-3%,5%-cyclic monophosphate binding protein, which contain glucosamine, galactose, mannose, inositol, phosphoric acid, ethanolamine and a peptide containing the sequence Asn-Cys-Tyr, their preparation and use for the treatment of diabetes mellitus and non-insulin-dependent diabetes are described.

公开(公告)号：ZA9206232B

公开(公告)日：1993-04-28

申请号：ZA9206232

申请日：1992-08-19

Applicant: HOECHST AG

Inventor： MUELLER GUENTER ,  GUENTER MUELLER ,  TRIPIER DOMINIQUE ,  DOMINIQUE TRIPIER ,  MUELLNER STEFAN ,  STEFAN MUELLNER

IPC: A61K38/28 ,  A61K31/715 ,  A61K38/00 ,  A61P3/08 ,  A61P3/10 ,  C07K1/22 ,  C07K5/08 ,  C07K5/093 ,  C07K5/10 ,  C07K9/00 ,  C07K14/37 ,  C07K14/41 ,  C07K14/475 ,  C07K14/575 ,  C07K14/62 ,  C07K14/65 ,  C12P19/26 ,  C12P21/00 ,  C12P21/02 ,  C12R1/865 ,  C07K

CPC classification number: C07K14/475 ,  A61K38/00 ,  C07K5/0827 ,  C07K5/1027 ,  C07K9/001 ,  C12P19/26