公开(公告)号：DE3601248A1

公开(公告)日：1987-07-23

申请号：DE3601248

申请日：1986-01-17

Applicant: HOECHST AG

Inventor： BREIPOHL GERHARD DR ,  KNOLLE JOCHEN DR ,  WEGMANN HELMUT DR ,  RUPPERT DIETER DR

IPC: C07K14/81 ,  A61K31/165 ,  A61K31/19 ,  A61K31/195 ,  A61K31/215 ,  A61K31/22 ,  A61K31/27 ,  A61K31/33 ,  A61K31/40 ,  A61K31/403 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4418 ,  A61K31/4427 ,  A61K31/4433 ,  A61K38/00 ,  A61P9/12 ,  A61P43/00 ,  C07D209/52 ,  C07D213/40 ,  C07D233/54 ,  C07D233/64 ,  C07D333/00 ,  C07D333/24 ,  C07D401/12 ,  C07D409/12 ,  C07D521/00 ,  C07K1/02 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/04 ,  C07K1/10

公开(公告)号：DE3721723A1

公开(公告)日：1989-01-12

申请号：DE3721723

申请日：1987-07-01

Applicant: HOECHST AG

Inventor： BARTMANN WILHELM PROF DR ,  GUNTRUM EBERHARD DR ,  URBACH HANSJOERG DR ,  WEGMANN HELMUT DR ,  GERHARDS HERMANN DR ,  KAISER JOACHIM DR ,  SCHACHT ULRICH DR

IPC: C07D217/24 ,  C07D217/04 ,  A61K31/47 ,  C07D217/06 ,  C07D217/16 ,  C07D217/20

Abstract: The invention relates to 6-oxodecahydroisoquinoline derivatives of the formula I in which R and R have the meanings indicated. In animal experiments, the compounds of the formula I show both a hypotensive action and an action on the central nervous system.

公开(公告)号：DE3610593A1

公开(公告)日：1987-10-01

申请号：DE3610593

申请日：1986-03-29

Applicant: HOECHST AG

Inventor： WEGMANN HELMUT DR ,  WAGNER ADALBERT DR ,  KLEEMANN HEINZ-WERNER DR ,  RUPPERT DIETER DR

IPC: C07K14/81 ,  A61K31/165 ,  A61K31/18 ,  A61K31/195 ,  A61K31/215 ,  A61K31/22 ,  A61K31/235 ,  A61K31/255 ,  A61K31/27 ,  A61P9/12 ,  A61P43/00 ,  C07C67/00 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C237/06 ,  C07C237/12 ,  C07C237/20 ,  C07C237/22 ,  C07C239/00 ,  C07C301/00 ,  C07C303/30 ,  C07C303/36 ,  C07C309/76 ,  C07C311/37 ,  C07C313/00 ,  C07C317/48 ,  C07C317/50 ,  C07C323/41 ,  C07D213/38 ,  C07D233/54 ,  C07D233/61 ,  C07D233/64 ,  C07D521/00 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  A61K37/64 ,  C07D213/40

公开(公告)号：DE3500898A1

公开(公告)日：1986-07-17

申请号：DE3500898

申请日：1985-01-12

Applicant: HOECHST AG

Inventor： KUNSTMANN RUDOLF DR ,  BRINKMANN LUDWIG DR ,  WEGMANN HELMUT DR ,  BICKEL MARTIN DR ,  HERLING ANDREAS DR

IPC: C07D209/14 ,  C07D211/14 ,  C07D211/70 ,  C07D295/15 ,  C07D401/04 ,  C07C103/34 ,  A61K31/16 ,  A61K31/44 ,  A61K31/445 ,  A61K31/495 ,  C07C103/38 ,  C07C103/46 ,  C07D211/82 ,  C07D295/12

Abstract: The invention relates to compounds of the general formula I in which A denotes a substituted aryl and B denotes optionally substituted aralkylamino, heteroalkylamino, optionally substituted arylpiperidino, heteroarylpiperidino, optionally substituted aryl piperazino, heteroarylpiperazino, optionally substituted aryl- tetrahydropyridinyl or heteroaryltetrahydropyridinyl, it being possible for one CH2 group to be replaced by O or S, and their salts, a process for the preparation of these compounds, compositions containing them, and their use.