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公开(公告)号:DE2557748A1
公开(公告)日:1977-06-30
申请号:DE2557748
申请日:1975-12-20
Applicant: HOECHST AG
Inventor: REUSCHLING DIETER-BERND DR , KUEHLEIN KLAUS DR , LINIES ADOLF DR , KUNSTMANN RUDOLF DR , MUSIL JOSEF DR
IPC: C07D207/26 , C07D207/273 , C07D207/38 , A61K31/40
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公开(公告)号:DE2444109A1
公开(公告)日:1976-03-25
申请号:DE2444109
申请日:1974-09-14
Applicant: HOECHST AG
Inventor: KUNSTMANN RUDOLF DR , KAISER JOACHIM DR
IPC: C07D217/22 , C07D217/24
Abstract: Dihydroisoquinolines (salts) are of formula (I): (where R1 is H, or 1-6C alkyl; R2 is dialkylamino alkyl and including radicals, the two alkyl gps. together with the N-atom completes a 5-7 membered satd. heterocyclic ring opt. substd. by O, S or NR and R is H, 1-4C alkyl or phenyl or R1 + R2 is an N contg. satd. ring of 5-6 atoms; R3 is phenyl opt. mono- or disubstd. by halogen, NO2, amino, sulphamoyl, acylamino or 1-4C alkyl, or pyridyl. R4 and R5 are H or 1-4C alkoxy and X is O of S). (I) are used as anti-arythmic agents.
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公开(公告)号:DE2438965A1
公开(公告)日:1976-02-26
申请号:DE2438965
申请日:1974-08-14
Applicant: HOECHST AG
Inventor: KUNSTMANN RUDOLF DR , KAISER JOACHIM DR
IPC: C07D217/22 , C07D295/125
Abstract: The invention relates to 3,4-dihydro-2H-isoquinolin-1-thiones and a process for preparing them.
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公开(公告)号:DE3642497A1
公开(公告)日:1988-06-23
申请号:DE3642497
申请日:1986-12-12
Applicant: HOECHST AG
Inventor: KUNSTMANN RUDOLF DR , HOCK FRANZ DR , WIEMER GABRIELE
IPC: C07D209/14 , A61K31/165 , A61K31/195 , A61K31/215 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/40 , A61K31/403 , A61K31/404 , A61K31/445 , A61K31/451 , A61K31/495 , A61P25/18 , A61P25/28 , C07C231/00 , C07C231/02 , C07C237/04 , C07C237/20 , C07C237/22 , C07D209/16 , C07D211/14 , C07D211/30 , C07D211/70 , C07D295/14 , C07D295/15 , C07D307/66 , C07D307/82 , C07D333/20 , C07D333/58 , C07C103/50 , C07D295/12 , C07D213/74 , C07D207/337 , C07D307/54 , C07D307/81 , C07D333/24 , C07D333/60 , A61K31/16
Abstract: Aminopropionic acid amides of the formula I in which A, X and Z have the meanings indicated, and their physiologically tolerable salts are used as medicaments in which these compounds in particular have nootropic action.
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公开(公告)号:DE3500898A1
公开(公告)日:1986-07-17
申请号:DE3500898
申请日:1985-01-12
Applicant: HOECHST AG
Inventor: KUNSTMANN RUDOLF DR , BRINKMANN LUDWIG DR , WEGMANN HELMUT DR , BICKEL MARTIN DR , HERLING ANDREAS DR
IPC: C07D209/14 , C07D211/14 , C07D211/70 , C07D295/15 , C07D401/04 , C07C103/34 , A61K31/16 , A61K31/44 , A61K31/445 , A61K31/495 , C07C103/38 , C07C103/46 , C07D211/82 , C07D295/12
Abstract: The invention relates to compounds of the general formula I in which A denotes a substituted aryl and B denotes optionally substituted aralkylamino, heteroalkylamino, optionally substituted arylpiperidino, heteroarylpiperidino, optionally substituted aryl piperazino, heteroarylpiperazino, optionally substituted aryl- tetrahydropyridinyl or heteroaryltetrahydropyridinyl, it being possible for one CH2 group to be replaced by O or S, and their salts, a process for the preparation of these compounds, compositions containing them, and their use.
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公开(公告)号:GR81850B
公开(公告)日:1984-12-12
申请号:GR840174194
申请日:1984-03-23
Applicant: HOECHST AG
Inventor: SCHMIDT KARL DR , KRUSE HANSJORG DR , SCHACT ULRICH DR , KUNSTMANN RUDOLF DR
IPC: A61K31/47 , A61K31/472 , A61P25/24 , A61P25/26 , C07D217/04
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公开(公告)号:DE2557343A1
公开(公告)日:1977-06-30
申请号:DE2557343
申请日:1975-12-19
Applicant: HOECHST AG
Inventor: BARTMANN WILHELM DR , KUNSTMANN RUDOLF DR , LERCH ULRICH DR , SCHOELKENS BERNHARD DR
IPC: A61K31/23 , A61K9/00 , A61K31/34 , A61K31/341 , A61K31/343 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/54 , C07D307/68 , C07D307/935 , C07C69/66 , A61K31/20 , C07C61/38
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公开(公告)号:DE2548814A1
公开(公告)日:1977-05-26
申请号:DE2548814
申请日:1975-10-31
Applicant: HOECHST AG
Inventor: BARTMANN WILHELM DR , KUNSTMANN RUDOLF DR , LERCH ULRICH DR , SCHOELKENS BERNHARD DR
IPC: C07D307/935 , A61K31/34 , A61K31/343 , C07C405/00 , C07D307/93
Abstract: The present invention relates to cyclopentane derivatives similar to prostaglandins. Due to their antiprostaglandin effect they have valuable properties as medicaments.
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公开(公告)号:DE2438966A1
公开(公告)日:1976-03-04
申请号:DE2438966
申请日:1974-08-14
Applicant: HOECHST AG
Inventor: KUNSTMANN RUDOLF DR , KAISER JOACHIM DR
IPC: C07D217/22 , C07D217/24 , C07D295/125 , A61K31/47
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公开(公告)号:DE3729598A1
公开(公告)日:1989-03-16
申请号:DE3729598
申请日:1987-09-04
Applicant: HOECHST AG
Inventor: SOHN ERICH DR , KUNSTMANN RUDOLF DR
IPC: C07D231/14
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