公开(公告)号：JP2010243514A

公开(公告)日：2010-10-28

申请号：JP2010177438

申请日：2010-08-06

Applicant: F Hoffmann-La Roche Ag ,  エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト

Inventor： BHULLAR RAGHBIR SINGH ,  SURRIDGE NIGEL A ,  FUNKE TOM ,  RIGGLES RANDALL K ,  WALLING PAUL DOUGLAS

IPC: G01N27/327 ,  G01N27/26 ,  G01N27/416 ,  G01N31/22 ,  G01N33/00 ,  G01N33/487 ,  G01N33/558

CPC classification number: G01N33/558 ,  G01N27/3271 ,  Y10T156/1059 ,  Y10T156/1084

Abstract: PROBLEM TO BE SOLVED: To provide a test strip with a sample-receiving chamber having a novel flared portion that terminates, in a sample-receiving opening. SOLUTION: The method for producing a test strip includes (a) a process which prepares a base substrate, a pitch layer and a cover layer; (b) a process which has an elongated section and a spherical section to form a space extending into the pitch layer; (c) a process which laminates a space layer on the base substrate used as the base and laminates the cover layer on the pitch layer to form a test strip precursor section; and (d) a cutting of a part of the precursor section, to produce the test strip, where a process is included, such that the cutting traverses a spherical section of the space formed at the process (b) to form a sample receiving edge of the test strip and the space demarcates the sample-receiving chamber which has an entrance section terminating within the sample receiving opening at the sample-receiving terminal edge of the test strip. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：为了提供具有样品接收室的测试条，其具有在样品接收开口中终止的新颖的扩口部分。 测试条的制造方法包括（a）准备基底基板，间距层和覆盖层的工序。 （b）具有细长部分和球形部分以形成延伸到沥青层中的空间的方法; （c）将用作基底的基底层叠空间层并层叠沥青层上的覆盖层以形成测试条前体部分的方法; 和（d）切割前体部分的一部分，以产生包含工艺的测试条，使得切割穿过在工艺（b）形成的空间的球形部分，以形成样品接收边缘 并且所述空间划分所述样品接收室，所述样品接收室具有终止于所述测试条的所述样品接收端边缘处的所述样品接收开口内的入口部分。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：WO2006074927A8

公开(公告)日：2007-08-23

申请号：PCT/EP2006000222

申请日：2006-01-12

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE

Inventor： RIGGLES RANDALL K ,  JOSEPH ABNER D ,  FUNKE TOM

IPC: G01N33/487 ,  G01N27/30 ,  G01N27/416

CPC classification number: G01N27/3272

Abstract: A test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces. In addition, conductive traces are positioned to ensure structural interrogation of all electrodes and traces present upon the test strip.

Abstract translation: 当测试条与适当的测试仪器配合时，用于测量生物流体中感兴趣的信号的测试条，其中测试条和测试仪器包括用于验证测试条迹线的完整性的结构，以测量寄生电阻 的测试条迹线，并且提供对施加到测试条的电压的补偿，以考虑测试条迹线中的寄生电阻损耗。 此外，定位导电迹线以确保在测试条上存在的所有电极和迹线的结构询问。

公开(公告)号：CA2838759C

公开(公告)日：2018-01-02

申请号：CA2838759

申请日：2012-07-25

Applicant: HOFFMANN LA ROCHE

Inventor： AUSTERA JOHN T ,  BEATY TERRY A ,  JOSEPH ABNER D ,  MANLOVE NATHAN E ,  MOORE STEVEN K ,  PAULEY JAMES L JR ,  RIGGLES RANDALL K

IPC: G01N27/327 ,  G01N33/487

Abstract: An analyte test sensor strip is disclosed having information coded thereon as well as a method of forming the same and conducting an analyte test using the analyte test sensor strip. Information relating to an attribute of the strip or batch/lot of strips may be coded based on resistance values pertaining to electrical aspects of the strip, such as a primary resistive element and a secondary resistive element, the secondary resistive element having one of a plurality of states defined by a location of a closed tap to form a unique resistive path for the secondary resistive element that includes a portion of the primary resistive element depending on the location of the closed tap. The states may be formed on the strip by a secondary processing step in the manufacture of the strip in which a plurality of taps are severed leaving only one tap in a closed state.

公开(公告)号：CA2529651C

公开(公告)日：2017-02-21

申请号：CA2529651

申请日：2004-06-18

Applicant: HOFFMANN LA ROCHE

Inventor： BHULLAR RAGHBIR SINGH ,  SURRIDGE NIGEL A ,  FUNKE TOM ,  RIGGLES RANDALL K ,  WALLING PAUL DOUGLAS

IPC: G01N27/30 ,  C12Q1/00 ,  G01N27/26 ,  G01N31/22 ,  G01N33/00 ,  G01N33/487 ,  G01N33/558

Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to "target" with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.

公开(公告)号：CA2901064C

公开(公告)日：2019-09-17

申请号：CA2901064

申请日：2014-03-13

Applicant: HOFFMANN LA ROCHE

Inventor： BEATY TERRY A ,  BUCK HARVEY E ,  CARPENTER SCOTT E ,  JOSEPH ABNER D ,  LICA GEORGETA C ,  RIGGLES RANDALL K

IPC: G01N27/327

Abstract: A biosensor including a capillary chamber having an inner boundary, a working electrode including an effective working electrode portion positioned within the capillary chamber, and a counter electrode including an effective counter electrode portion positioned within the capillary chamber, and with the working and counter electrodes each having a neck that constitutes the sole portion of the electrodes that extends across the inner boundary and out of the capillary chamber. In one embodiment, the effective working electrode portion defines an average working electrode width, and the working electrode neck defines a working electrode neck width that is reduced relative to the average working electrode width. In another embodiment, a ratio between the area of the effective working electrode portion exposed to the capillary chamber and the area of the effective counter electrode portion exposed to the capillary chamber is substantially constant as a position of the inner boundary of the capillary chamber is varied along a length of the working and counter electrode necks.

公开(公告)号：PL1846761T3

公开(公告)日：2017-12-29

申请号：PL06703387

申请日：2006-01-12

Applicant: HOFFMANN LA ROCHE

Inventor： JOSEPH ABNER D ,  FUNKE TOM ,  RIGGLES RANDALL K

IPC: G01N27/327 ,  G01N27/416 ,  G01N33/487

公开(公告)号：HK1219537A1

公开(公告)日：2017-04-07

申请号：HK16107557

申请日：2016-06-29

Applicant: HOFFMANN LA ROCHE

Inventor： BEATY TERRY A ,  BUCK JR HARVEY E ,  CARPENTER SCOTT E ,  JOSEPH ABNER D ,  LICA GEORGETA C ,  RIGGLES RANDALL K

IPC: G01N20060101

公开(公告)号：ES2681398T3

公开(公告)日：2018-09-12

申请号：ES04755692

申请日：2004-06-18

Applicant: HOFFMANN LA ROCHE

Inventor： BHULLAR RAGHBIR SINGH ,  SURRIDGE NIGEL A ,  FUNKE TOM ,  RIGGLES RANDALL K ,  WALLING PAUL DOUGLAS

IPC: G01N27/30 ,  C12Q1/00 ,  G01N27/26 ,  G01N31/22 ,  G01N33/00 ,  G01N33/487 ,  G01N33/558

Abstract: Una tira reactiva (10, 300, 350, 400, 500, 512, 524) para analizar un líquido, que comprende: un cuerpo de tira reactiva que define una cámara de recepción de muestra (24, 354, 404, 504, 516) que tiene una porción ensanchada (328, 352, 402, 518, 530, 532) que termina en un orificio de recepción de líquido y una porción alargada (332, 532) que se extiende hacia el interior desde la porción ensanchada (328, 352, 402, 518, 530, 532), en el que la porción alargada (332, 532) se define por un par de paredes laterales opuestas sustancialmente paralelas y una pared de extremo que conecta las paredes laterales, y en el que la porción ensanchada (328, 352, 402, 518, 530, 532) se define por un par de paredes que se estrechan en una dirección hacia la porción alargada (332, 532); definiendo el cuerpo de tira reactiva una ventilación en comunicación con la cámara de recepción de muestra (24, 354, 404, 504, 516), por lo que el aire puede escapar de la ventilación a medida que el líquido es aspirado en la cámara de recepción de muestra (24, 354, 404, 504, 516); comprendiendo el cuerpo de tira reactiva además: un sustrato de base (12), una capa de cubierta (16) que cubre el sustrato de base (12) y una capa espaciadora (14) intercalada entre el sustrato de base (12) y la capa de cubierta (16), definiendo la capa espaciadora (14) un vacío que define el perímetro de la cámara de recepción de muestra (24, 354, 404, 504, 516) entre el sustrato de base (12) y la capa de cubierta (16); y comprendiendo la tira reactiva (10, 300, 350, 400, 500, 512, 524) además un área de prueba dispuesta en la cámara de recepción de muestra (24, 354, 404, 504, 516) para analizar el líquido; en la que el orificio de recepción de líquido (35) está dispuesto en un extremo de recepción de líquido cónico de la tira reactiva (10, 300, 350, 400, 500, 512, 524).

公开(公告)号：MX2012014620A

公开(公告)日：2013-02-07

申请号：MX2012014620

申请日：2011-06-30

Applicant: HOFFMANN LA ROCHE

Inventor： DIEBOLD ERIC R ,  RIGGLES RANDALL K ,  JOSEPH ABNER DAVID ,  BEATY TERRY A

IPC: G01N33/487

Abstract: Algunas modalidades de la invención incluyen una técnica de fabricación de 2 o más para producir tiras reactivas (100) para reducir costos, reducir desperdicio e incrementar el rendimiento. También se describen otras técnicas con relación a la técnica de 2 o más, tal como fabricar simultáneamente tiras reactivas (100) arregladas en múltiples columnas. Aun otras técnicas incluyen cortar a través de los sustratos superior (110) e inferior (130) para formar una saliente de ya sea el sustrato superior (110) o inferior (130). Otras modalidades incluyen un biosensor de uso dual en el cual un usuario puede aplicar una muestra de fluido corporal a ambas tiras reactivas de forma simultánea.

公开(公告)号：CA2529651A1

公开(公告)日：2004-12-29

申请号：CA2529651

申请日：2004-06-18

Applicant: HOFFMANN LA ROCHE

Inventor： BHULLAR RAGHBIR SINGH ,  SURRIDGE NIGEL A ,  RIGGLES RANDALL K ,  FUNKE TOM ,  WALLING PAUL DOUGLAS

IPC: G01N27/30 ,  C12Q1/00 ,  G01N27/26 ,  G01N31/22 ,  G01N33/00 ,  G01N33/487 ,  G01N33/558

Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to "target" with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test stri p and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample flui d into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.