公开(公告)号：JP2006346450A

公开(公告)日：2006-12-28

申请号：JP2006156212

申请日：2006-06-05

Applicant: HOFFMANN LA ROCHE

Inventor： WERNER KARL ,  STEPHAN PETER ,  LORENZ ROBERT

IPC: A61B5/1473 ,  G01N33/66 ,  G06F19/00

Abstract: PROBLEM TO BE SOLVED: To provide a method of giving the information that blood glucose density measurement is needed to a user at each suitable time. SOLUTION: This glucose analyzer includes : a measuring device 6 for measuring the glucose density; a display device 4 for displaying the glucose density; a signal device 10 for generating a scheduled confirming signal; and a control and evaluating device 7 including a processor and a data memory 8 and used for deciding the scheduled confirming time for actuating the signal device 10. The data memory 8 stores an event and time data including events corresponding to prescribed various events which occur in the living of a user of the glucose analyzer and information on the occurrence time of the event. The confirmed schedule time is determined according to a confirmed schedule time deciding algorithm taking the events and time data over two or more days. COPYRIGHT: (C)2007,JPO&INPIT

公开(公告)号：WO2006119914A3

公开(公告)日：2007-02-01

申请号：PCT/EP2006004179

申请日：2006-05-04

Applicant: HOFFMANN LA ROCHE ,  ROCHE DIAGNOSTICS GMBH ,  FERRARI STEFANO ,  QUARDER ORTRUD ,  STEPHAN PETER

Inventor： FERRARI STEFANO ,  QUARDER ORTRUD ,  STEPHAN PETER

IPC: A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/14528 ,  A61B5/1473

Abstract: The invention relates to a method and a device for determining the glucose concentration in tissue liquid (40). Said method and device are used for detecting (sensor 12) measured values for glucose and an endogenous reference substance in a sample liquid (42) obtained by means of microdialysis, microperfusion, or ultrafiltration (probe 10) and correcting the glucose value in accordance with the measured value for the reference substance. The invention is characterized in that the glucose recovery rate is determined from a non-linear correlation with the recovery rate for the ionic reference substance while the measured value for glucose is corrected therewith. Furthermore, the lactate concentration and/or pyruvate concentration is/are used as (an) additional reference substance(s) in the sample liquid to make further corrections.

Abstract translation: 本发明涉及一种用于确定在组织液从而在通过微透析微灌或超滤（探针10）中得到的葡萄糖浓度（40），样品液体的方法和装置，（42）的记录测定的葡萄糖和用于内源对照品值（传感器 12）根据所述测量值中的葡萄糖值的参考物质校正。 这里提出，用于从与回收率为离子对照品被确定并且该葡萄糖测量值的非线性关系葡萄糖的回收率与它纠正，并且还作为在用于进一步校正的样本液体中的另外的参考物质的乳酸和/或丙酮酸的浓度 被使用。

公开(公告)号：PL3380839T3

公开(公告)日：2020-03-31

申请号：PL16800918

申请日：2016-11-21

Applicant: HOFFMANN LA ROCHE

Inventor： IBACH ALEXANDER ,  RINGEMANN CHRISTIAN ,  STEPHAN PETER

IPC: G01N21/84 ,  C12Q1/00 ,  G01N21/78

公开(公告)号：AT547046T

公开(公告)日：2012-03-15

申请号：AT06010874

申请日：2006-05-26

Applicant: HOFFMANN LA ROCHE

Inventor： WERNER KARL ,  STEPHAN PETER ,  LORENZ ROBERT

IPC: A61B5/145 ,  G06F19/00

Abstract: A glucose analysis device comprising a display device for displaying glucose concentration values determined by a measuring device, and a control-and analysis device (7) with a data storage for storing event time data including information about events, where the events belong to a predefined event in the living tissue of a user of the device, and the analysis device determines a reminder time by a reminder time determining algorithm using the event time data of several days, and a signaling device (10) is activated at the reminder time to generate a reminder signal, is new.

公开(公告)号：CA2550170A1

公开(公告)日：2006-12-18

申请号：CA2550170

申请日：2006-06-14

Applicant: HOFFMANN LA ROCHE

Inventor： LORENZ ROBERT ,  STEPHAN PETER ,  WERNER KARL

IPC: A61B5/00 ,  A61B5/155 ,  A61G99/00 ,  A61J7/04 ,  G01N33/66 ,  G06F19/00

Abstract: Glucose analysis instrument for diabetics, comprising a measuring device (6) for determining glucose concentration values, a displaying device (4) for displaying glucose concentration values, a signaling device (10) for generating a reminder signal, and a control and evaluation device (7) that comprises a processor and a data memory (8) and is used to determine reminder times at which the signaling device (10) is actuated. Event time data are stored in the data memory (8), said event time data containing information on events which belong to a predefined event type in the life of a user of the glucose analysis instrument and on the time of occurrence of said events. The reminder times are determined by means of a reminder time determination algorithm taking into consideration event time data from a plurality of days. >

公开(公告)号：CA2607396A1

公开(公告)日：2006-11-16

申请号：CA2607396

申请日：2006-05-04

Applicant: HOFFMANN LA ROCHE

Inventor： QUARDER ORTRUD ,  FERRARI STEFANO ,  STEPHAN PETER

IPC: A61B5/00

Abstract: The invention relates to a method and a device for determining the glucose concentration in tissue liquid (40). Said method and device are used for detecting (sensor 12) measured values for glucose and an endogenous referenc e substance in a sample liquid (42) obtained by means of microdialysis, microperfusion, or ultrafiltration (probe 10) and correcting the glucose val ue in accordance with the measured value for the reference substance. The invention is characterized in that the glucose recovery rate is determined from a non-linear correlation with the recovery rate for the ionic reference substance while the measured value for glucose is corrected therewith. Furthermore, the lactate concentration and/or pyruvate concentration is/are used as (an) additional reference substance(s) in the sample liquid to make further corrections.

公开(公告)号：HUE047960T2

公开(公告)日：2020-05-28

申请号：HUE16800918

申请日：2016-11-21

Applicant: HOFFMANN LA ROCHE

Inventor： IBACH ALEXANDER ,  RINGEMANN CHRISTIAN ,  STEPHAN PETER

IPC: G01N21/84 ,  C12Q1/00 ,  G01N21/78

公开(公告)号：CA3000297C

公开(公告)日：2021-11-02

申请号：CA3000297

申请日：2016-11-21

Applicant: HOFFMANN LA ROCHE

Inventor： IBACH ALEXANDER ,  RINGEMANN CHRISTIAN ,  STEPHAN PETER

IPC: G01N33/52 ,  G01N21/84

Abstract: The invention concerns a method and an apparatus for determining the concentration of an analyte in a body fluid, where the following measures are proposed: providing a layered test element (12) including an enzyme-based chemistry layer which is responsive to the analyte by a color change, applying a sample of the body fluid onto the test element (12), detecting by means of a photometric reflectance measuring device (16) a reflectance value of the test element (12), correcting the measured reflectance value by a predetermined offset value attributed to the test element (12), determining a concentration value of the analyte using the offset- corrected reflectance value.

公开(公告)号：CA3000297A1

公开(公告)日：2017-06-01

申请号：CA3000297

申请日：2016-11-21

Applicant: HOFFMANN LA ROCHE

Inventor： IBACH ALEXANDER ,  RINGEMANN CHRISTIAN ,  STEPHAN PETER

IPC: G01N33/52 ,  G01N21/84

Abstract: The invention concerns a method and an apparatus for determining the concentration of an analyte in a body fluid, where the following measures are proposed: providing a layered test element (12) including an enzyme-based chemistry layer which is responsive to the analyte by a color change, applying a sample of the body fluid onto the test element (12), detecting by means of a photometric reflectance measuring device (16) a reflectance value of the test element (12), correcting the measured reflectance value by a predetermined offset value attributed to the test element (12), determining a concentration value of the analyte using the offset- corrected reflectance value.