Operation of diagnostic devices involving microchannels and electrodes

    公开(公告)号:GB2547753A

    公开(公告)日:2017-08-30

    申请号:GB201621803

    申请日:2016-12-21

    Applicant: IBM

    Abstract: An assembly for interfacing with a microfluidic chip 238 having at least one microscopic channel with at least one embedded electrode configured to receive a liquid sample for analysis and at least one chip contact coupled to the electrode, the assembly comprising a chip carrier 240, an electronics module 110, an optical module 118 and a mechanical module. The chip carrier includes a base and a cover which define a cavity 236 for receiving the chip, and at least one chip carrier contact 234 to engage with the chip contact. The electronics module comprises at least one electronic module contact 248 which engage with the chip carrier contacts and a signal generator which applies at least one electrokinetic signal to the embedded electrode(s) of the chip via the electronic module contacts. The optical module includes an excitation radiation source and an emission radiation detector. The mechanical module is controlled by the electronics module and comprises a chip-carrier receiving structure, relatable with respect to the optical module for focus and at least one degree of translational freedom. The embedded electrodes are ideally dielectrophoresis electrodes. A method of carrying out a test on a microfluidic chip employing impedance changes is also disclosed.

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