公开(公告)号：WO1997040858A1

公开(公告)日：1997-11-06

申请号：PCT/US1997005908

申请日：1997-04-02

Applicant: IMARX PHARMACEUTICAL CORP.

Inventor： IMARX PHARMACEUTICAL CORP. ,  UNGER, Evan, C. ,  FRITZ, Thomas ,  MATSUNAGA, Terry ,  RAMASWAMI, VaradaRajan ,  YELLOWHAIR, David ,  WU, Guanli

IPC: A61K49/04

CPC classification number: A61K9/1277 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1278 ,  A61K41/0028 ,  A61K41/0052 ,  A61K49/22 ,  A61K49/223 ,  A61K49/227 ,  A61M5/3145 ,  G01R33/5601

Abstract: Lyophilized lipid compositions, as well as methods for their preparation, are embodied by the present invention. Gas-filled microspheres prepared using the lyophilized lipid composition are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.

Abstract translation: 冻干脂质组合物及其制备方法由本发明体现。 使用冻干的脂质组合物制备的充气微球在例如超声成像应用和治疗药物递送系统中是特别有用的。

公开(公告)号：EP0923383A1

公开(公告)日：1999-06-23

申请号：EP97920281.0

申请日：1997-04-02

Applicant: IMARX PHARMACEUTICAL CORP.

Inventor： UNGER, Evan, C. ,  FRITZ, Thomas ,  MATSUNAGA, Terry ,  RAMASWAMI, VaradaRajan ,  YELLOWHAIR, David ,  WU, Guanli

IPC: A61B8 ,  A61K8 ,  A61K9 ,  A61K41 ,  A61K47 ,  A61K49 ,  A61Q19 ,  B01J13 ,  G01R33 ,  A61M5

CPC classification number: A61K9/1277 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1278 ,  A61K41/0028 ,  A61K41/0052 ,  A61K49/22 ,  A61K49/223 ,  A61K49/227 ,  A61M5/3145 ,  G01R33/5601

Abstract: Lyophilized lipid compositions, as well as methods for their preparation, are embodied by the present invention. Gas-filled microspheres prepared using the lyophilized lipid composition are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.

公开(公告)号：EP0740528A1

公开(公告)日：1996-11-06

申请号：EP95908414.0

申请日：1994-11-30

Applicant: Imarx Pharmaceutical Corp.

Inventor： UNGER, Evan C. ,  MATSUNAGA, Terry ,  YELLOWHAIR, David

IPC: A61K8 ,  A61K9 ,  A61K41 ,  A61K47 ,  A61K49 ,  A61Q1 ,  A61Q19 ,  A61M5

CPC classification number: A61K9/1271 ,  A61K8/14 ,  A61K8/70 ,  A61K9/127 ,  A61K9/1277 ,  A61K9/1278 ,  A61K41/0028 ,  A61K41/0052 ,  A61K47/6925 ,  A61K49/1815 ,  A61K49/22 ,  A61K49/223 ,  A61K49/227 ,  A61K2800/87 ,  A61M5/3145 ,  A61Q19/00 ,  Y10S436/829

Abstract: Gas and gaseous precursor filled microspheres (1), and foams thereof, provide novel topical and subcutaneous delivery vehicles for various active ingredients, including drugs and cosmetics (2).