中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

45 records (took 0.033 seconds)

    NOVEL SILICON AMPHIPHILIC COMPOUNDS AND THE USE THEREOF
    2.
    发明申请
    NOVEL SILICON AMPHIPHILIC COMPOUNDS AND THE USE THEREOF 审中-公开
    新型硅酮化合物及其用途

    公开(公告)号：WO1998009600A2

    公开(公告)日：1998-03-12

    申请号：PCT/US1997015033

    申请日：1997-08-26

    Applicant: IMARX PHARMACEUTICAL CORP.

    Inventor： IMARX PHARMACEUTICAL CORP. ,  UNGER, Evan, C. ,  SHEN, DeKANG ,  WU, Guanli

    IPC: A61K00/00

    CPC classification number: A61K51/1227 ,  A61K49/1806 ,  A61K49/223 ,  C07F7/0838

    Abstract: Novel silicon amphiphilic compounds which comprise a silicon residue. The silicon amphiphilic compounds are particularly suitable for use in compositions for diagnostic imaging, such as ultrasound. Compositions of the silicon amphiphilic compounds comprise a gas or gaseous precursor, and may take the form of vesicle compositions, such as micelles or liposomes.

    Abstract translation: 包含硅残渣的新型硅两亲化合物。 硅两亲化合物特别适用于用于诊断成像的组合物，例如超声波。 硅两亲化合物的组合物包含气体或气体前体，并且可以采取囊泡组合物的形式，例如胶束或脂质体。

    METHODS AND APPARATUS FOR PERFORMING DIAGNOSTIC AND THERAPEUTIC ULTRASOUND SIMULTANEOUSLY
    4.
    发明申请
    METHODS AND APPARATUS FOR PERFORMING DIAGNOSTIC AND THERAPEUTIC ULTRASOUND SIMULTANEOUSLY 审中-公开
    用于同时执行诊断和治疗超声的方法和装置

    公开(公告)号：WO1996039079A1

    公开(公告)日：1996-12-12

    申请号：PCT/US1996007621

    申请日：1996-05-24

    Applicant: IMARx PHARMACEUTICAL CORP.

    Inventor： IMARx PHARMACEUTICAL CORP. ,  UNGER, Evan, C. ,  YELLOWHAIR, David, W.

    IPC: A61B08/00

    CPC classification number: A61B8/12 ,  A61B8/0833 ,  A61B8/0883 ,  A61B8/445 ,  A61B8/4483 ,  A61B8/481 ,  A61K41/0028 ,  A61K49/223 ,  A61N7/00 ,  G01S15/8925 ,  G01S15/899

    Abstract: Methods and apparatus (12-102) for performing diagnostic ultrasound simultaneously with the application of therapeutic ultrasonic waves are disclosed. The methods and apparatus (12-102) are particularly advantageous in performing ultrasonic imaging of a region of a patient while simultaneously applying therapeutic ultrasonic waves to the region for the purpose of rupturing vesicles administered to that region for purposes such as enhanced cavitation or the targeted release of a bioactive agent into the region. An operator is able to monitor the rupture of vesicles in real time.

    Abstract translation: 公开了与应用治疗超声波同时执行诊断超声的方法和装置（12-102）。 方法和装置（12-102）在对患者的区域进行超声波成像同时对该区域施加治疗性超声波以便为了破坏施用于该区域的囊泡的目的而特别有利，例如增强的空化或靶向 将生物活性剂释放到该区域。 操作者能够实时监测囊泡破裂。

    IMPROVED METHODS FOR DIAGNOSTIC IMAGING USING A CONTRAST AGENT AND A VASODILATOR
    5.
    发明申请
    IMPROVED METHODS FOR DIAGNOSTIC IMAGING USING A CONTRAST AGENT AND A VASODILATOR 审中-公开
    改进的使用对比剂和血管扩张剂进行诊断成像的方法

    公开(公告)号：WO1998010798A1

    公开(公告)日：1998-03-19

    申请号：PCT/US1997014957

    申请日：1997-08-26

    Applicant: IMARX PHARMACEUTICAL CORP.

    Inventor： IMARX PHARMACEUTICAL CORP. ,  UNGER, Evan, C.

    IPC: A61K49/00

    CPC classification number: A61B5/411 ,  A61B5/201 ,  A61K49/223 ,  A61K49/227

    Abstract: A method for providing an image of an internal region of a patient has been developed. The method reduces imaging artifacts by providing enhanced contrast between tissue and blood during imaging. The method comprises administering to a patient a contrast agent in combination with a renal vasodilator and performing ultrasound imaging of the region. Renal disease, including renal arterial stenosis, may be diagnosed using the method.

    Abstract translation: 已经开发了用于提供患者的内部区域的图像的方法。 该方法通过在成像期间通过提供组织和血液之间的增强的对比来减少成像伪像。 该方法包括向患者施用与肾血管扩张剂组合的造影剂并对该区域进行超声成像。 可以使用该方法诊断肾脏疾病，包括肾动脉狭窄。

    IMPROVED METHODS FOR DIAGNOSTIC IMAGING INVOLVING THE USE OF A CONTRAST AGENT AND A CORONARY VASODILATOR
    7.
    发明申请
    IMPROVED METHODS FOR DIAGNOSTIC IMAGING INVOLVING THE USE OF A CONTRAST AGENT AND A CORONARY VASODILATOR 审中-公开
    涉及使用对比剂和冠状血管扩张剂的诊断成像的改进方法

    公开(公告)号：WO1998010799A1

    公开(公告)日：1998-03-19

    申请号：PCT/US1997014986

    申请日：1997-08-26

    Applicant: IMARx PHARMACEUTICAL CORP.

    Inventor： IMARx PHARMACEUTICAL CORP. ,  UNGER, Evan, C.

    IPC: A61K49/04

    CPC classification number: A61B5/411 ,  A61B5/201 ,  A61K49/223 ,  A61K49/227

    Abstract: Improved method for providing an image of an internal region of a patient, especially the cardiovascular region. Embodiments of the invention involve the administration to the patient of a contrast agent which comprises a vesicle composition comprising lipid or polymer vesicles and a gas or gaseous precursor, in combinationwith a coronary vasodilator. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The methods are particularly useful for diagnosing the presence of diseased tissue in the cardiovascular region of a patient, as well as for measuring blood flow in the cardiovascular region of a patient.

    Abstract translation: 用于提供患者，特别是心血管区域的内部区域的图像的改进方法。 本发明的实施方案涉及向患者施用造影剂，其包含与冠状血管扩张剂组合的包含脂质或聚合物囊泡和气体或气体前体的囊泡组合物。 使用诸如超声波之类的诊断成像扫描患者，以获得该区域的可见图像。 该方法对于诊断患者的心血管区域中的患病组织的存在以及用于测量患者的心血管区域中的血流量是特别有用的。

    IMPROVED METHODS FOR DIAGNOSTIC IMAGING BY REGULATING THE ADMINISTRATION RATE OF A CONTRAST AGENT
    8.
    发明申请
    IMPROVED METHODS FOR DIAGNOSTIC IMAGING BY REGULATING THE ADMINISTRATION RATE OF A CONTRAST AGENT 审中-公开
    通过调整对比剂的行政率进行诊断成像的改进方法

    公开(公告)号：WO1997048337A1

    公开(公告)日：1997-12-24

    申请号：PCT/US1997010510

    申请日：1997-06-16

    Applicant: IMARX PHARMACEUTICAL CORP.

    Inventor： IMARX PHARMACEUTICAL CORP. ,  UNGER, Evan, C. ,  MATSUNAGA, Terry, O. ,  FRITZ, Thomas, A. ,  RAMASWAMI, Varada, Rajan

    IPC: A61B05/055

    CPC classification number: A61K49/223 ,  Y10S977/801 ,  Y10S977/927 ,  Y10S977/928 ,  Y10S977/929 ,  Y10S977/93

    Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

    Abstract translation: 提供患者内部区域的图像的方法。 该方法的实施方案涉及向患者施用造影剂，其包含囊泡组合物，所述囊泡组合物在水性载体中包含气体或气体前体和包含脂质，蛋白质或聚合物的囊泡。 使用诸如超声波之类的诊断成像扫描患者，以获得该区域的可见图像。 将造影剂以基本上消除图像中的诊断伪像的速率施用于患者。 该方法对于诊断患者中任何患病组织的存在特别有用。

Patent Agency Ranking