BIOSENSOR, DEVICE AND METHOD FOR DETECTING NUCLEIC ACIDS BY MEANS OF AT LEAST TWO UNITS FOR IMMOBILIZING NUCLEIC ACIDS
    1.
    发明申请
    BIOSENSOR, DEVICE AND METHOD FOR DETECTING NUCLEIC ACIDS BY MEANS OF AT LEAST TWO UNITS FOR IMMOBILIZING NUCLEIC ACIDS 审中-公开
    生物传感器,设备和方法核酸检测由至少两个单位的核酸固定

    公开(公告)号:WO02074984A3

    公开(公告)日:2003-04-03

    申请号:PCT/DE0200867

    申请日:2002-03-12

    CPC classification number: C12Q1/6834 G01N33/5438

    Abstract: The invention relates to a biosensor for detecting nucleic acids, comprising at least two units for immobilizing nucleic acids and one electrical detection circuit. Said units are electroconductive and electrically insulated from one another. The units are provided with first nucleic acid molecules that are present as single-stranded molecules and that are capable of binding second nucleic acids to be detected. These scavenger molecules are provided with a redox-active marker that is capable of producing a detectable signal. The electrical detection circuit is adapted to detect by means of the marker any nucleic acid molecules bound to the scavenger molecules.

    Abstract translation: 用于检测核酸的生物传感器具有至少两个单元用于固定的核酸,和电检测电路。 这些单元是导电的,并且彼此电绝缘。 单元设置有其存在作为单链分子可以结合与被检测到的第二核酸分子第一核酸分子。 这些捕获分子设置有氧化还原活性标记能够产生可检测信号。 电检测电路被配置为使得其检测已经通过所述标签的装置结合到捕获分子的核酸分子。

    SWITCHING CIRCUIT SYSTEM, ELECTROCHEMICAL SENSOR, SENSOR SYSTEM, AND METHOD FOR PROCESSING A CURRENT SIGNAL MADE AVAILABLE VIA A SENSOR ELECTRODE
    2.
    发明申请
    SWITCHING CIRCUIT SYSTEM, ELECTROCHEMICAL SENSOR, SENSOR SYSTEM, AND METHOD FOR PROCESSING A CURRENT SIGNAL MADE AVAILABLE VIA A SENSOR ELECTRODE 审中-公开
    电路布置的电化学传感器,用于加工通过传感器电极传感器系统和方法提供的功率信号

    公开(公告)号:WO03067238A2

    公开(公告)日:2003-08-14

    申请号:PCT/DE0300123

    申请日:2003-01-17

    CPC classification number: G01N27/3276

    Abstract: The invention relates to a switching circuit system, an electrochemical sensor, a sensor system, and a method for processing a current signal made available via a sensor electrode. The inventive switching circuit system comprises a sensor electrode, a first circuit unit that is electrically coupled to the sensor electrode, and a second circuit unit which is provided with a first capacitor. The first circuit unit is arranged in such a way that it maintains the electric potential of the sensor electrode within a predefined first reference range at a predefined electric set point potential by coupling the first capacitor to the sensor electrode such that the electric potential can be adjusted. The second circuit unit is arranged in such a way that it detects any deviation of the electric potential of the first capacitor from a second reference range and brings the first capacitor to a first electric reference potential.

    Abstract translation: 本发明涉及一种电路装置,电化学传感器,一个传感器装置和用于处理通过传感器电极提供的电流信号的方法。 该电路装置具有传感器电极,第一电路单元,其被电耦合到所述传感器电极和第二电路单元包括第一电容器,其中,所述第一电路单元被布置成使得的电位 保持可预先确定的电势所需的传感器在预先给定的第一基准范围电极由所述第一电容器和传感器电极以这样的方式,该电势的匹配是可能的耦合。 此外,第二电路单元被布置成使得当所述第一电容器的电位是第二基准范围之外时,检测到这个事件,并且使第一电容器到第一电基准电位。

    DNA CHIP COMPRISING A MICROARRAY MADE OF MICROELECTRODE SYSTEMS

    公开(公告)号:CA2510720C

    公开(公告)日:2012-02-14

    申请号:CA2510720

    申请日:2003-12-15

    Abstract: The invention relates to a DNA chip comprising a carrier (14) and a microarray of spots (1) containing immobilised catcher molecules which are arranged on said carrier. Each spot (1) contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution (38) applied to the spots (1). The microelectrode system has a pair of polarisation electrodes (2,4) in order to produce an alternating electromagnetic field and a pair of sensor electrodes (8,10) for measuring a voltage drop in the analyte (38).

    6.
    发明专利
    未知

    公开(公告)号:DE10224567A1

    公开(公告)日:2003-12-18

    申请号:DE10224567

    申请日:2002-06-03

    Abstract: Sensor arrangement having capture molecules immobilized on any of three sensor electrodes, wherein molecules to be detected can hybridize with the capture molecules; a control circuit for applying a first electrical signal to a selected sensor electrode and simultaneously applying a second electrical signal to at least two of the other sensor electrodes; a detection device, wherein in a first operating state a reference liquid is introduced into the sensor arrangement and a reference value of an electrical signal is detected at the selected sensor electrode, and in a second operating state an analyte possibly having molecules to be detected is introduced into the sensor arrangement and a sensor value of the electrical signal is detected at the selected sensor electrode; and an evaluation circuit, which, on the basis of the reference value and the sensor value, determines whether a hybridization event has taken place at the selected sensor electrode.

    Transistor-diode combination module with substrate

    公开(公告)号:DE10101951A1

    公开(公告)日:2002-08-01

    申请号:DE10101951

    申请日:2001-01-17

    Abstract: The substrate contains a P-doped trough region, in which is formed an N-doped source region and an N-doped drain region. Between the source and drain region is located an insulation layer and carries a gate region. A drain electrode is coupled to the drain region and a source electrode to the source region. To the trough region is linked a trough electrode for energizing the PN-junction between the trough and drain regions as a diode. The doping polarities may be inverted.

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