Abstract:
The invention relates to a biosensor for detecting nucleic acids, comprising at least two units for immobilizing nucleic acids and one electrical detection circuit. Said units are electroconductive and electrically insulated from one another. The units are provided with first nucleic acid molecules that are present as single-stranded molecules and that are capable of binding second nucleic acids to be detected. These scavenger molecules are provided with a redox-active marker that is capable of producing a detectable signal. The electrical detection circuit is adapted to detect by means of the marker any nucleic acid molecules bound to the scavenger molecules.
Abstract:
The invention relates to a switching circuit system, an electrochemical sensor, a sensor system, and a method for processing a current signal made available via a sensor electrode. The inventive switching circuit system comprises a sensor electrode, a first circuit unit that is electrically coupled to the sensor electrode, and a second circuit unit which is provided with a first capacitor. The first circuit unit is arranged in such a way that it maintains the electric potential of the sensor electrode within a predefined first reference range at a predefined electric set point potential by coupling the first capacitor to the sensor electrode such that the electric potential can be adjusted. The second circuit unit is arranged in such a way that it detects any deviation of the electric potential of the first capacitor from a second reference range and brings the first capacitor to a first electric reference potential.
Abstract:
An integrated circuit arrangement (300) has at least one electronic component (302), and also at least one resistance determining circuit that is coupled to the electronic component and is monolithically integrated with the latter and serves for determining the parasitic non-reactive resistance (303) of at least the lead to the at least one electronic component.
Abstract:
The invention relates to a DNA chip comprising a carrier (14) and a microarray of spots (1) containing immobilised catcher molecules which are arranged on said carrier. Each spot (1) contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution (38) applied to the spots (1). The microelectrode system has a pair of polarisation electrodes (2,4) in order to produce an alternating electromagnetic field and a pair of sensor electrodes (8,10) for measuring a voltage drop in the analyte (38).
Abstract:
Biosensor array (700) comprising a substrate (601), on which biosensors (602) are mounted which have two connectors, is new. One of these (603) is connected to a control lead (605) while the other (604) is connected to a detector lead (606). A control unit supplies a signal to the desired biosensor and the detector lead feeds the signal produced by it to a processor. Independent claims are also included for: (a) a similar array in which control and detector leads are both replaced by signal leads (b) a method for operating the array with control and detector leads; and (c) a method for operating the array with signal leads.
Abstract:
Sensor arrangement having capture molecules immobilized on any of three sensor electrodes, wherein molecules to be detected can hybridize with the capture molecules; a control circuit for applying a first electrical signal to a selected sensor electrode and simultaneously applying a second electrical signal to at least two of the other sensor electrodes; a detection device, wherein in a first operating state a reference liquid is introduced into the sensor arrangement and a reference value of an electrical signal is detected at the selected sensor electrode, and in a second operating state an analyte possibly having molecules to be detected is introduced into the sensor arrangement and a sensor value of the electrical signal is detected at the selected sensor electrode; and an evaluation circuit, which, on the basis of the reference value and the sensor value, determines whether a hybridization event has taken place at the selected sensor electrode.
Abstract:
The substrate contains a P-doped trough region, in which is formed an N-doped source region and an N-doped drain region. Between the source and drain region is located an insulation layer and carries a gate region. A drain electrode is coupled to the drain region and a source electrode to the source region. To the trough region is linked a trough electrode for energizing the PN-junction between the trough and drain regions as a diode. The doping polarities may be inverted.
Abstract:
A switching circuit arrangement is disclosed. The arrangement includes a substrate, a plurality of functional units arranged on the substrate, a plurality of selection line groups including selection lines, a plurality of signal line groups including signal lines, a buffer unit for each signal line group, a selection unit which is coupled to the selection line groups, and a signal unit which is coupled to the signal lines.
Abstract:
The circuit arrangement has a first charge pump circuit with a first amplifier stage with a first pump node, a second amplifier stage with a second pump node and a charge reservoir circuit with a first coupling node coupled to the first pump node and a second coupling code coupled to the second pump node. The pump nodes store excess charge carrier. AN Independent claim is also included for the following: a contactless chip card with an inventive circuit arrangement.