公开(公告)号：EP3561059A1

公开(公告)日：2019-10-30

申请号：EP17885347.9

申请日：2017-12-22

Applicant: Institute for Basic Science

Inventor： KIM, Jin-Soo ,  KIM, Kyoung Mi ,  RYU, Seuk Min

IPC: C12N15/10 ,  C12N15/85 ,  C12N15/877 ,  C12N9/16 ,  C12N9/78 ,  C12N9/02 ,  C07K14/47

Abstract: Provided are a base editing composition comprising deaminase and target-specific nuclease, a base editing method using the base editing composition, and a method for producing a genetically modified animal. The base editing composition has a base editing activity in mammalian embryos.

公开(公告)号：EP3744844A1

公开(公告)日：2020-12-02

申请号：EP19743145.5

申请日：2019-01-23

Applicant: Institute for Basic Science

Inventor： KIM, Jin-Soo ,  LIM, Ka Yeong ,  KANG, Beum-Chang ,  RYU, Seuk Min

IPC: C12N15/113 ,  C12N15/10 ,  C12N15/90 ,  C12N9/22

Abstract: The present disclosure relates to: an extended guide RNA and a composition for base editing, comprising the same; and a method for base editing and a method for producing genetically modified animals or plants, both methods using the composition for base editing.