公开(公告)号：WO2016108451A3

公开(公告)日：2016-10-13

申请号：PCT/KR2015013252

申请日：2015-12-04

Applicant: KOREA BASIC SCIENCE INST

Inventor： YANG MO ,  KIM SEUNG YONG ,  KIM HYUN SIK ,  JEONG WAN SEOP

IPC: H01J49/40

CPC classification number: H01J49/147 ,  H01J43/246 ,  H01J49/08 ,  H01J49/142 ,  H01J49/40

Abstract: A time-of-flight mass spectrometer comprises: an ionization unit for receiving an electron beam and emitting ions; a cold electron supply unit for injecting an electron beam into the ionization unit; an ion detection unit for detecting ions discharged from the ionization unit; and an ion separation unit for connecting the ionization unit and the ion detection unit, wherein the cold electron supply unit comprises a microchannel plate, which receives ultraviolet rays and emits an electron beam, ions discharged from the ionization unit pass through the ion separation unit and reach the ion detection unit, and the ion separation unit has the shape of a straight tube.

Abstract translation: 飞行时间质谱仪包括：用于接收电子束并发射离子的电离单元; 用于将电子束注入电离单元的冷电子供应单元; 离子检测单元，用于检测从电离单元排出的离子; 以及用于连接电离单元和离子检测单元的离子分离单元，其中冷电子供给单元包括接收紫外线并发射电子束的微通道板，从电离单元排出的离子穿过离子分离单元，以及 到达离子检测单元，并且离子分离单元具有直管的形状。

公开(公告)号：WO2012074234A3

公开(公告)日：2012-07-26

申请号：PCT/KR2011008866

申请日：2011-11-21

Applicant: KOREA BASIC SCIENCE INST ,  CHOI MYOUNG CHOUL ,  PARK A LEUM ,  KIM HYUN SIK ,  KIM SEUNG YONG ,  YOO JONG SHIN

Inventor： CHOI MYOUNG CHOUL ,  PARK A LEUM ,  KIM HYUN SIK ,  KIM SEUNG YONG ,  YOO JONG SHIN

IPC: G01N27/62 ,  H01J49/26

CPC classification number: H01J49/02 ,  H01J49/0027 ,  H01J49/065 ,  H01J49/38

Abstract: A Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) includes: an ionization source generating ions; a deceleration lens, on which the ions generated by the ionization source and spatially dispersed are incident, selectively decelerating the incident ions so as to decrease the distance between the ions; and an ion cyclotron resonance cell on which the ions passing through the deceleration lens are incident. By preventing dispersing of ions due to mass difference and converging the ions using the deceleration lens, the mass range that can be measured at one time can be extended. Also, measurement sensitivity can be improved since the ions are effectively introduced to the ICR cell.

Abstract translation: 傅立叶变换离子回旋共振质谱仪（FT-ICR MS）包括：产生离子的电离源; 一个减速透镜，在该减速透镜上，由电离源产生并在空间上分散的离子入射，有选择地使入射离子减速，从而减小离子之间的距离; 以及其上通过减速透镜的离子入射在其上的离子回旋共振单元。 通过防止因质量差引起的离子扩散并使用减速透镜会聚离子，可以延长一次可测量的质量范围。 而且，由于离子被有效地引入ICR单元，所以可以提高测量灵敏度。

公开(公告)号：WO2011081298A3

公开(公告)日：2011-11-03

申请号：PCT/KR2010008079

申请日：2010-11-16

Applicant: KOREA BASIC SCIENCE INST ,  KIM SEUNG YONG ,  KIM HYUN SIK ,  YOO JONG SHIN

Inventor： KIM SEUNG YONG ,  KIM HYUN SIK ,  YOO JONG SHIN

IPC: H01J49/34 ,  G01N27/62 ,  H01J49/26

CPC classification number: H01J49/38 ,  H01J49/022

Abstract: The present invention relates to an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, in which an ion trap unit of the ion cyclotron resonance mass spectrometer is capable of using two digitizers at the same time, thus enabling a measurement process for detecting an electrical signal which indicates the mass of ions corresponding to a specific purpose, and another measurement process for detecting another electrical signal which indicates the mass of ions corresponding to another specific purpose, to be simultaneously performed. Accordingly, it is an aim of the present invention to provide an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, which can overcome the problems of time delay among control procedures, and can present a signal detection step wherein an excitation electrode is utilized to improve the sensitivity and speed of signal detection.

Abstract translation: 本发明涉及一种用于控制管道型离子回旋共振质谱仪的装置和方法，其中离子回旋共振质谱仪的离子阱单元能够同时使用两个数字转换器，从而能够进行测量过程 用于检测指示对应于特定目的的离子的质量的电信号以及用于检测指示与另一特定目的对应的离子的质量的另一电信号的另一测量过程被同时执行。 因此，本发明的一个目的是提供一种用于控制流水线式离子回旋共振质谱仪的装置和方法，该装置和方法可以克服控制过程中时间延迟的问题，并且可以提供一种信号检测步骤，其中激励 电极用于提高信号检测的灵敏度和速度。

公开(公告)号：KR101146229B1

公开(公告)日：2012-05-17

申请号：KR20100129681

申请日：2010-12-17

Applicant: KOREA BASIC SCIENCE INST

Inventor： KIM SEUNG YONG ,  KIM HYUN SIK ,  CHOI MYOUNG CHOUL ,  YOO JONG SHIN

IPC: H01J49/26 ,  G01N27/62

CPC classification number: H01J49/02 ,  H01J49/022 ,  H01J49/38

Abstract: PURPOSE: A control device for improving signal capability of an ion cyclotron resonance mass spectrograph is provided to improve signal sensibility by supplying voltage for ion movement and controlling deflection. CONSTITUTION: An excitation electrode control means applies a high frequency signal or a control signal from a high-frequency amplifier(7) to a first excitation electrode and a second excitation electrode. A detection electrode control means applies an arbitrary waveforms generated in first and second control signal generating units(21, 23) to each detection electrode. A detection electrode signal processing signal detects an ion signal from first and second detection electrodes and amplifies and changes the ion signal into a digital signal. An excitation electrode signal processing means detects an ion signal from the first and second excitation electrodes. The excitation electrode signal processing means amplifies and changes the ion signal into the digital signal. A first excitation switching unit(12) selectively outputs by a computer control program.

Abstract translation: 目的：提供一种用于提高离子回旋共振质谱仪信号能力的控制装置，通过提供离子运动电压和控制偏转来提高信号灵敏度。 构成：励磁电极控制装置将高频信号或来自高频放大器（7）的控制信号施加到第一激励电极和第二激励电极。 检测电极控制装置将在第一和第二控制信号产生单元（21,23）中产生的任意波形施加到每个检测电极。 检测电极信号处理信号检测来自第一和第二检测电极的离子信号，并将离子信号放大并变换为数字信号。 励磁电极信号处理装置检测来自第一和第二激励电极的离子信号。 激励电极信号处理装置将离子信号放大并变换为数字信号。 第一激励切换单元（12）通过计算机控制程序有选择地输出。

公开(公告)号：KR20120039839A

公开(公告)日：2012-04-26

申请号：KR20100101270

申请日：2010-10-18

Applicant: KOREA BASIC SCIENCE INST

Inventor： CHOI MYOUNG CHOUL ,  KIM HYUN SIK ,  KIM SEUNG YONG

IPC: G01N27/62 ,  H01L21/265 ,  H05H13/00

CPC classification number: H01J49/38

Abstract: PURPOSE: A Fourier transform ion cyclotron resonance mass spectrometer using ultra-wideband RF amplifier and a method for improving signal of Fourier transform ion cyclotron resonance mass spectrometer are provided to add DC offset to high voltage signal by using wide operation frequency range. CONSTITUTION: A Fourier transform ion cyclotron resonance mass spectrometer comprises a signal generating unit(10), a voltage amplifier(20), a ion cyclotron trap(30). The signal generating unit generates a sine wave shaped first voltage signal having DC offset. The voltage amplifier receives the first voltage signal from the signal generating unit, and generates a second voltage signal. The ion cyclotron trap receives the second voltage signal, and generates ion cyclotron action around the location determined by the DC offset.

Abstract translation: 目的：提供使用超宽带RF放大器的傅里叶变换离子回旋共振质谱仪和傅里叶变换离子回旋共振质谱仪的信号改进方法，通过使用宽工作频率范围向高压信号增加直流偏移。 构成：傅里叶变换离子回旋共振质谱仪包括信号发生单元（10），电压放大器（20），离子回旋加速器捕集器（30）。 信号产生单元产生具有DC偏移的正弦波状的第一电压信号。 电压放大器从信号发生单元接收第一电压信号，并产生第二电压信号。 离子回旋收集器接收第二电压信号，并且在由DC偏移确定的位置周围产生离子回旋加速器作用。

公开(公告)号：KR100659263B1

公开(公告)日：2006-12-12

申请号：KR20060007815

申请日：2006-01-25

Applicant: KOREA BASIC SCIENCE INST

Inventor： KIM SEUNG YONG ,  HUR MAN HOI ,  KIM SUNG HWAN ,  KIM HYUN SIK ,  YOO JONG SHIN

IPC: G01N27/62

Abstract: A method for controlling a tandem mass analyzer of pipeline type is provided to independently operate a test material injection section, a first ion transfer section, an ion selection/separation section, an ion collision section, and a second ion transfer section. A method for controlling a tandem mass analyzer of pipeline type includes the steps of: operating a first ion transfer section and operating a second ion transfer section by a control unit(S28); operating an ion selection/separation section and operating a trap section by the control unit(S29); and colliding ions selected or separated by the ion selection/separation section and dividing the ions into a small size and discharging the ions and operating the test material injection section(S29a).

Abstract translation: 提供了一种用于控制管道类型的串联质量分析器的方法，以独立地操作测试材料注入部分，第一离子转移部分，离子选择/分离部分，离子碰撞部分和第二离子转移部分。 一种用于控制管道类型的串联质量分析器的方法包括以下步骤：操作第一离子转移部分并通过控制单元操作第二离子转移部分（S28）; 操作离子选择/分离部分并由控制单元操作陷阱部分（S29）; 和离子选择/分离部选择或分离的离子碰撞，并将离子分成小尺寸并排出离子并操作测试材料注入部分（S29a）。

公开(公告)号：DE102008064246B4

公开(公告)日：2013-02-21

申请号：DE102008064246

申请日：2008-12-22

Applicant: KOREA BASIC SCIENCE INST

Inventor： CHOI MYOUNG CHOUL ,  CHOI YEON SUK ,  LEE JEONG MIN ,  KIM SEUNG YONG ,  KIM DONG LAK ,  KIM HYUN SIK ,  YOO JONG SHIN ,  STAHL STEFAN KARL-HEINZ

IPC: H01J49/26 ,  G01N27/62 ,  H01J49/38

Abstract: Fouriertransformation-Ionenzyklotronresonanz-Massenspektrometer, das umfasst: eine Ionisierungsquelle (101), um eine Probe einzuleiten, ein Massenfilter (102), um ein in eine Vakuumkammer eingeleitetes Ion auszuwählen und zu speichern, eine Kollisionszelle (103) und einen Ionenübertragungsleiter (104), um das gespeicherte Ion zu einer Ionenzyklotronresonanz-Falle (105) zu übertragen, die ein Signal misst, wobei die Ionisierungsquelle (101), der Massenfilter (102), die Kollisionszelle (103), der Ionenübertragungsleiter (104) und die Ionenzyklotronresonanz-Falle (105) in der Vakuumkammer angeordnet sind, gekennzeichnet durch ein Erfassungssystem, das einen Kryo-Vorverstärker (200) aufweist, der die Signale der Ionenzyklotronresonanz-Falle (105) verstärkt, und der in der Vakuumkammer so nahe wie möglich bei der Ionenzyklotronresonanz-Falle (105) installiert ist, und ein Kryo-Kühlungssystem (300), das einen Kryo-Kühler (301) und ein Kryogen-Zirkulationsrohr (302, 302-1) aufweist, die außerhalb der Vakuumkammer installiert sind, um den Kryo-Vorverstärker (200) zu kühlen, und einen Kryo-Kühlungsflansch (303), der am dem Kryo-Kühlsystem (300) zugewandten Ende der Vakuumkammer vorgesehen ist und der...

公开(公告)号：DE102008064246A1

公开(公告)日：2009-07-09

申请号：DE102008064246

申请日：2008-12-22

Applicant: KOREA BASIC SCIENCE INST

Inventor： CHOI MYOUNG CHOUL ,  CHOI YEON SUK ,  LEE JEONG MIN ,  KIM SEUNG YONG ,  KIM DONG LAK ,  KIM HYUN SIK ,  YOO JONG SHIN ,  STAHL STEFAN KARL-HEINZ

IPC: H01J49/26 ,  G01N27/62

Abstract: A Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) is provided. A preamplifier is installed as nearest to an ion cyclotron resonance (ICR) trap as possible at a detector part in the mass spectrometer, and thermal noise generated at the preamplifier is minimized by means of a cryo-cooling system to increase a signal-to-noise ratio of ion detection signals such that an ultra-low amount of specimen can be detected, which was impossible in the related art.