公开(公告)号：WO2009014315A1

公开(公告)日：2009-01-29

申请号：PCT/KR2008/003283

申请日：2008-06-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Su Nam ,  LEE, Woo Jung ,  KWON, Hak Cheol ,  HAM, Jungyeob ,  AHN, Hong Ryul ,  KIM, Myung Soo ,  NAM, Chun-Woo ,  LEE, Jong-Nam ,  LIM, Ju-Sung ,  PARK, Hyun Bong ,  PARK, Yeon-Suk

Inventor： KIM, Su Nam ,  LEE, Woo Jung ,  KWON, Hak Cheol ,  HAM, Jungyeob ,  AHN, Hong Ryul ,  KIM, Myung Soo ,  NAM, Chun-Woo ,  LEE, Jong-Nam ,  LIM, Ju-Sung ,  PARK, Hyun Bong ,  PARK, Yeon-Suk

IPC: A61K36/48 ,  C07C43/00

CPC classification number: A61K36/48 ,  C07C39/21 ,  C07D311/32

Abstract: The present invention relates to a composition containing the extract of Robinia pseudo-acacia var. umbraculifera(Robinia pseudo-acacia var. umbraculifera) , fractions thereof and compounds isolated therefrom as an active ingredient, more precisely a composition containing the extract of Robinia pseudo-acacia var. umbraculifera extracted with water, alcohol or a mixture thereof as a solvent, fractions thereof and compounds isolated therefrom such as amorphastilbol or 5, 7-dihydroxy-6-geranyl flavanone, or its pharmaceutically acceptable salts which can activate peroxisome proliferator-activated receptor (PPAR) to bring the effect of prevention or treatment of obesity, diabetes, inflammation, skin aging, wrinkles. So, the extract of Robinia pseudo-acacia var. umbraculifera , fractions thereof and compounds isolated therefrom of the present invention can be effectively used as an active ingredient for medicines, food and drink or compositions for skin external application.

Abstract translation: 本发明涉及含有刺槐提取物的组合物。 芜菁（Robinia pseudo-acacia var。umbraculifera），其分数和作为活性成分分离的化合物，更确切地说是含有刺槐提取物的组合物。 以水，醇或其作为溶剂的混合物，其馏分和从其分离的化合物如阿莫法星或5,7-二羟基-6-香叶基黄烷酮或其可以活化过氧化物酶体增殖物激活受体（PPAR）的药学上可接受的盐提取 ）带来预防或治疗肥胖，糖尿病，炎症，皮肤老化，皱纹的效果。 所以，刺槐拟提取物 本发明的级分和与其分离的化合物可以有效地用作药物，食品和饮料或外用皮肤组合物的活性成分。

公开(公告)号：EP3517175A1

公开(公告)日：2019-07-31

申请号：EP19152993.2

申请日：2019-01-22

Applicant: Korea Institute of Science and Technology

Inventor： PAN, Cheol-Ho ,  KANG, Kyungsu ,  KIM, Sang Min ,  JUNG, Sang Hoon ,  AHN, Hong Ryul ,  EOM, Jae-In ,  KOO, Song Yi ,  CHOI, Yongsoo ,  YANG, Jung-Seok ,  LEE, Eun Ha ,  LEE, Hee Ju ,  KIM, Kyung A

IPC: A61P27/06 ,  A61K36/05 ,  A23L17/00 ,  A61P27/02

Abstract: The present disclosure discloses a composition for improving eye health comprising Tetraselmis sp. microalgae; a culture thereof; a crushed material thereof; or an extract of the microalgae, the culture or the crushed material as an active ingredient. The composition inhibits retinal optic nerve damage and thereby improves eye health.