公开(公告)号：EP4467147A1

公开(公告)日：2024-11-27

申请号：EP23743449.3

申请日：2023-01-18

Applicant: Korea Institute of Science and Technology

Inventor： CHOI, Ki Young ,  CHA, Kwang-Hyun ,  HAN, Hwa Seung ,  PARK, Jin Soo ,  SONG, Dae-geun ,  KIM, Myung Suk ,  KWON, Hak Cheol

IPC: A61K35/74 ,  A61K35/745 ,  A61P29/00 ,  A23L33/135 ,  A23K10/16 ,  A61P1/00

Abstract: The present invention relates to a composition for preventing, ameliorating, or treating inflammatory diseases comprising extracellular vesicles (EVs) derived from Roseburia spp. strains and/or Bifidobacterium spp. strains. The EVs of the present invention exhibits effectiveness in improving inflammatory bowel disease (IBD), and additionally, all EVs derived from congeneric strains corresponding to Roseburia spp. strains or Bifidobacterium spp. strains. have been confirmed to exhibit strong anti-inflammatory effect. As such, the strain of the present invention and EVs derived therefrom can be provided as a composition for preventing, ameliorating, or treating a variety of inflammatory diseases.

公开(公告)号：EP4032619A1

公开(公告)日：2022-07-27

申请号：EP21193052.4

申请日：2021-08-25

Applicant: Korea Institute of Science and Technology

Inventor： LEE, Byung Chul ,  KANG, Dong-Hyun ,  SHIM, Shinyong ,  KIM, Dong Jun ,  PARK, Jin Soo ,  PAHK, Ki Joo ,  SEONG, Hyejeong

IPC: B05B17/00 ,  A61M11/00

Abstract: A mesh type atomizer according to an embodiment includes a porous thin film having a multi-hole structure, a metal layer covering a remaining area except a nozzle area in which droplets are sprayed through the holes on a surface of the porous thin film, and an ultrasonic transducer to output ultrasonic waves to vibrate the porous thin film. According to an embodiment, it is possible to atomize a liquid into nanometer-level fine particles using the porous thin film including nanometer sized holes. It is possible to precisely adjust the sprayed droplet size by setting the shape, size and cycle of the nozzle in the manufacturing process, and it is possible to selectively increase the strength of the mesh by growing the metal material in the hole of the porous thin film through electroplating.

公开(公告)号：EP4467148A1

公开(公告)日：2024-11-27

申请号：EP23743450.1

申请日：2023-01-18

Applicant: Korea Institute of Science and Technology

Inventor： CHOI, Ki Young ,  HAN, Hwa Seung ,  CHA, Kwang-Hyun ,  SONG, Dae-geun ,  PARK, Jin Soo ,  LEE, Choong-Gu ,  KIM, Myung Suk

IPC: A61K35/74 ,  A61K35/745 ,  A61P1/16 ,  A23L33/135 ,  A23K10/16

Abstract: The present invention relates to a composition for the prevention, amelioration or treatment of non-alcoholic fatty liver disease (NAFLD), comprising a Roseburia spp. strain, a Bifidobacterium spp. strain, or extracellular vesicles (EVs) derived therefrom. The Roseburia spp. strain, the Bifidobacterium spp. strain, or the EVs derived therefrom, according to the present invention, can restore liver function, ameliorate liver steatosis and inflammation, and suppress liver fibrosis, and thus can be provided as a composition for the prevention, amelioration or treatment of NAFLD.