公开(公告)号：WO2016090076A3

公开(公告)日：2016-08-11

申请号：PCT/US2015063593

申请日：2015-12-03

Applicant: LIFE TECHNOLOGIES CORP

Inventor： ZHOU WENJUN ,  GEE KYLE ,  TENNICO YOLANDA ,  SLADE PETER ,  KANG HEE CHOL ,  KHAN SHAHEER ,  EVANS BRIAN ,  STRAY JAMES

IPC: C07D261/00 ,  G01N33/58

CPC classification number: C07C309/47 ,  C07C309/51 ,  C07C2603/50 ,  C07D311/84 ,  G01N33/582 ,  G01N2400/10

Abstract: The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate, phosphate, phosphonate, and/or carboxylate groups and dye compounds containing an aminooxy substitutent. The compounds are useful in the detection of analytes containing aldehyde and ketone groups, including, for example, glycans.

Abstract translation: 本公开内容涉及含有肼基取代基和任选地一个或多个带负电基团（例如磺酸根，磷酸根，膦酸根和/或羧酸根基团）和含有氨氧基取代基的染料化合物的染料化合物。 这些化合物可用于检测含有醛和酮基的分析物，包括例如聚糖。