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    SYSTEM AND METHOD FOR CONTROL OF SEQUENCING PROCESS
    1.
    发明申请
    SYSTEM AND METHOD FOR CONTROL OF SEQUENCING PROCESS 审中-公开

    公开(公告)号：WO2022146708A1

    公开(公告)日：2022-07-07

    申请号：PCT/US2021/063838

    申请日：2021-12-16

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： REED, Mark ,  PODHASKY, Joseph ,  SHANKAR, Shanti

    IPC: C12N15/10 ,  C12Q1/6869 ,  G16B30/00 ,  G16B50/00

    Abstract: A method for determining a sequence of nucleic acids includes purifying the nucleic acids from a sample with a purification instrument in accordance with a purification plan of a run plan. The purified nucleic acids are disposed in a transfer plate. Disposition of the purified nucleic acids is stored in a transfer file. The method further includes transferring the transfer plate to a sequencing instrument; transferring the transfer file to the sequencing instrument; and sequencing the nucleic acids with the sequencing instrument in accordance with a sequencing plan of the run plan and based on the transfer file.

    SYSTEMS AND METHODS FOR PROVIDING FLUIDIC ACCESS TO A FLOW CELL
    4.
    发明申请
    SYSTEMS AND METHODS FOR PROVIDING FLUIDIC ACCESS TO A FLOW CELL 审中-公开

    公开(公告)号：WO2021034709A1

    公开(公告)日：2021-02-25

    申请号：PCT/US2020/046502

    申请日：2020-08-14

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： HOSHIZAKI, Jon ,  LEUNG, Patrick ,  MARRAN, David ,  REED, Mark

    IPC: G01N35/10 ,  B01L3/00

    Abstract: An apparatus includes a fluidic coupler including an opening. A first port is in fluid communication with the opening and is to interface with an inlet of a flow cell of a sensor device. A second port is to interface with an outlet of the flow cell of the sensor device. A third port is in fluidic communication with the second port. The apparatus further includes a mechanical assembly moveable between a first position and a second position. The fluidic coupler is secured to the flow cell of the sensor device in the first position. The fluidic coupler is disengaged from the flow cell of the sensor device in the second position.

    DEVICES INCORPORATING A MULTILANE FLOW CELL
    5.
    发明申请
    DEVICES INCORPORATING A MULTILANE FLOW CELL 审中-公开

    公开(公告)号：WO2021034705A1

    公开(公告)日：2021-02-25

    申请号：PCT/US2020/046481

    申请日：2020-08-14

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： BUIE, Creighton ,  REED, Mark ,  CARRILLO, Albert

    IPC: B01L3/00 ,  G01N27/414

    Abstract: A sensor device includes a substrate having a die attached to the substrate. The die includes an array of sensors and an array of wells cooperatively disposed over the array of sensors. The array of wells is exposed by the substrate. The sensor device further includes a flow cell secured to the substrate and defining a flow space disposed over the die and accessible to the array of wells. The flow cell defines a plurality of separate volumes. Each separate volume of the plurality of separate volumes has an inlet and an outlet. The plurality of separate volumes are separated by dividers. The dividers cover a set of wells of the array of wells.

    SYSTEM AND METHOD FOR POLYNUCLEOTIDE PURIFICATION
    7.
    发明申请
    SYSTEM AND METHOD FOR POLYNUCLEOTIDE PURIFICATION 审中-公开

    公开(公告)号：WO2022104224A1

    公开(公告)日：2022-05-19

    申请号：PCT/US2021/059410

    申请日：2021-11-15

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： PODHASKY, Joseph ,  KANE, Nathan ,  REED, Mark

    IPC: G01N1/34 ,  C12N15/10 ,  G01N1/40 ,  G01N33/543 ,  G01N35/00

    Abstract: A system includes a pipetting system including a 3-axis gantry; a sled mechanism to select a magnetic comb from a set of magnetic combs; a fluorometer; and a set of receptacles to receive welled plates. A method for purifying nucleic acids includes applying a sample to a well of a multi-well plate, selecting a magnetic comb from a set of magnetic combs disposed on a gantry system, collecting magnetic beads using the magnetic comb, collecting nucleic acid using the magnetic beads, and eluting the nucleic acid from the beads.

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