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    APPARATUSES, SYSTEMS AND METHODS FOR PROVIDING SCALABLE THERMAL CYCLERS AND ISOLATING THERMOELECTRIC DEVICES
    1.
    发明申请
    APPARATUSES, SYSTEMS AND METHODS FOR PROVIDING SCALABLE THERMAL CYCLERS AND ISOLATING THERMOELECTRIC DEVICES 审中-公开
    用于提供可扩展热循环和隔离热电装置的装置，系统和方法

    公开(公告)号：WO2015126621A1

    公开(公告)日：2015-08-27

    申请号：PCT/US2015/014357

    申请日：2015-02-04

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： LIM, Chee Kiong ,  LEE, Way Xuang ,  LOH, Wuh Ken ,  CHING, Chee Wee ,  KOO, Chin Yong ,  KOH, Siew Ying ,  TOH, Tiong Han ,  BOO, Kuan Moon ,  LAU, Soo Yong

    IPC: B01L7/00

    CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1883 ,  C12Q1/6806

    Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.

    Abstract translation: 一方面，公开了一种包括样品块和热电装置的热循环仪系统。 在各种实施例中，样品块具有构造成容纳多个反应容器和相对的第二表面的第一表面。 在各种实施例中，热电装置可操作地耦合到样品块的第二表面。 在各种实施例中，提供了热控制单元。 在各种实施例中，热控制单元包括计算机处理单元。 在各种实施例中，热控制单元包括电流源。 在各种实施例中，热控制单元还包括被配置为通过电缆将热电装置与电流源连接的电接口部分。 在各种实施例中，热控制单元定向在与样品块和热电冷却器不同的平面中。

    SYSTEMS AND METHODS FOR ASSESSING BIOLOGICAL SAMPLES
    2.
    发明申请
    SYSTEMS AND METHODS FOR ASSESSING BIOLOGICAL SAMPLES 审中-公开
    用于评估生物样本的系统和方法

    公开(公告)号：WO2016127128A1

    公开(公告)日：2016-08-11

    申请号：PCT/US2016/016886

    申请日：2016-02-05

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： CHEN, Mingsong ,  BOO, Kuan Moon ,  TOH, Tiong Han ,  AGUANNO, Mauro ,  LAU, Soo Yong ,  YEO, Huei Steven ,  TEO, Wei Fuh

    IPC: G01N21/64 ,  G02B21/24

    CPC classification number: C12Q1/686 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/168 ,  B01L2300/18 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6458 ,  G01N2021/6463 ,  G02B21/244

    Abstract: Systems and Methods for Assessing Biological Samples An instrument (100) for biological analysis includes a base (300), an excitation source (402), an optical sensor (408), an excitation optical system (400), and an emission optical system (400). The base is configured to receive a sample holder (305) comprising a plurality of biological samples (310). The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear (455) that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture (478) disposed along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface (432) near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.

    Abstract translation: 用于生物样品评估的系统和方法用于生物分析的仪器（100）包括基底（300），激发源（402），光学传感器（408），激发光学系统（400）和发射光学系统 400）。 基座被配置为接收包括多个生物样品（310）的样品架（305）。 光学传感器被配置为响应于激发源接收来自生物样品的发射。 仪器还可以包括由透镜壳体包围的传感器透镜和聚焦机构，该聚焦机构包括与透镜壳体接合的齿轮（455），该聚焦机构可在外壳外面进行调节以调整焦点。 仪器还可以包括沿着发射光路设置的传感器孔径（478）和被设置为与传感器孔径配合的阻挡结构，使得来自样品架附近的被照射表面（432）的反射辐射不被 光学传感器也不会反射出仪器的另一个表面。

    THERMAL CYCLER COVER
    4.
    发明申请
    THERMAL CYCLER COVER 审中-公开
    热循环盖

    公开(公告)号：WO2014149268A1

    公开(公告)日：2014-09-25

    申请号：PCT/US2014/016397

    申请日：2014-02-14

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： TOH, Tiong Han ,  LOH, Wuh Ken ,  BOO, Kuan Moon ,  KLEIN, Sandro David ,  WELSH, Daniel

    IPC: B01L7/00

    CPC classification number: B01L7/52 ,  B01L2300/043 ,  B01L2300/1822

    Abstract: [0032] In one aspect, a thermal cycler system is disclosed. The thermal cycler can be comprised of a device housing and a cover that is operably connected to the device housing. The cover can include a handle portion, a device lid portion, a sample block platen and a link bar. The device lid portion is attached to the proximal side of the handle portion with a pin. The sample block platen is operably connected to the handle portion such that the sample block platen is positioned against the sample block when the handle portion is flush with the device lid portion and the cover is in a closed position. The link bar is operably connected to the device housing and the pin such that a distal side of the handle portion is elevated away from the device lid portion when the cover is moved to an open position.

    Abstract translation: 在一个方面，公开了一种热循环仪系统。 热循环仪可以由装置壳体和可操作地连接到装置壳体的盖组成。 盖可以包括手柄部分，装置盖部分，样品块压板和连杆。 装置盖部分用销钉安装在把手部分的近侧。 样品块压板可操作地连接到手柄部分，使得当手柄部分与装置盖部分齐平并且盖处于关闭位置时，样品块压板位于样品块上。 连杆可操作地连接到装置壳体和销上，使得当盖移动到打开位置时把手部分的远端从装置盖部分升高。

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