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    SAMPLE-TO-ANSWER MICROFLUIDIC CARTRIDGE
    1.
    发明专利
    SAMPLE-TO-ANSWER MICROFLUIDIC CARTRIDGE 未知

    公开(公告)号：CA2786569C

    公开(公告)日：2019-04-09

    申请号：CA2786569

    申请日：2011-01-28

    Applicant: MICRONICS INC

    Inventor： BATTRELL C FREDERICK ,  SPRAGUE ISAAC ,  BRAGD MATTHEW SCOTT ,  CAPODANNO JASON

    IPC: B01L3/00

    Abstract: A microfluidic cartridge and methods for performing a diagnostic, molecular or biochemical assay thereon, where all dried and/or liquid reagents necessary for the assay are contained in the cartridge and the assay requires only the addition of sample. Pneumohydraulic features, chamber and diaphragm technologies are introduced for overcoming the problems of bubble interference and reagent washout during operation of a microfluidic cartridge. The cartridges are inserted into a host instrument for performance of an assay and the cartridge is supplied as a consumable.

    SAMPLE-TO-ANSWER MICROFLUIDIC CARTRIDGE
    2.
    发明专利
    SAMPLE-TO-ANSWER MICROFLUIDIC CARTRIDGE 未知

    公开(公告)号：CA2786569A1

    公开(公告)日：2011-08-04

    申请号：CA2786569

    申请日：2011-01-28

    Applicant: MICRONICS INC

    Inventor： BATTRELL C FREDERICK ,  SPRAGUE ISAAC ,  BRAGD MATTHEW SCOTT ,  CAPODANNO JASON

    IPC: B01L3/00

    Abstract: A microfluidic cartridge and methods for performing a diagnostic, molecular or biochemical assay thereon, where all dried and/or liquid reagents necessary for the assay are contained in the cartridge and the assay requires only the addition of sample. Pneumohydraulic features, chamber and diaphragm technologies are introduced for overcoming the problems of bubble interference and reagent washout during operation of a microfluidic cartridge. The cartridges are inserted into a host instrument for performance of an assay and the cartridge is supplied as a consumable.

    LOW ELASTICITY FILMS FOR MICROFLUIDIC USE
    4.
    发明申请
    LOW ELASTICITY FILMS FOR MICROFLUIDIC USE 审中-公开
    用于微流体应用的低弹性膜

    公开(公告)号：WO2014100743A2

    公开(公告)日：2014-06-26

    申请号：PCT/US2013077269

    申请日：2013-12-20

    Applicant: MICRONICS INC

    Inventor： SPRAGUE ISAAC ,  KAY JUSTIN L ,  BRAGD MATTHEW SCOTT ,  BATTRELL C FREDERICK

    IPC: F04B9/02

    CPC classification number: B01L3/502707 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2400/06 ,  F04B19/006 ,  F04B43/043 ,  F16K99/0015 ,  F16K99/0055 ,  F16K2099/0084

    Abstract: Microfluidic circuit elements, such as a microvalve, micropump or microvent, formed of a microcavity divided by a diaphragm web into a first subcavity bounded by a first internal wall and a second subcavity bounded by a second internal wall, where the diaphragm web is characterized as a thin film having a first state contacting the first internal wall and a second state contacting the second internal wall and exhibiting essentially no elasticity in moving between the first state and the second state, the thin film web having been stretched beyond its yield point before or during use are provided. The disclosed elements enable faster and more efficient cycling of the diaphragm in the microcavity and increases the diaphragm surface area. In a preferred embodiment, the microfluidic circuit element is pneumatically driven and controls the motion of fluids in a microassay device.

    Abstract translation: 微流体回路元件，例如微型阀，微型泵或微型阀，其由被隔膜腹板分成的微腔形成为由第一内壁和由第二内壁界定的第二子腔界定的第一子腔，其中隔膜腹板的特征在于 具有与第一内壁接触的第一状态和与第二内壁接触并且在第一状态和第二状态之间移动时基本上没有弹性的第二状态的薄膜，所述薄膜卷材在之前已经被拉伸超过其屈服点或 在使用期间提供。 所公开的元件能够更快速和更有效地使微腔中的隔膜循环并且增加隔膜表面积。 在一个优选实施例中，微流体回路元件是气动驱动的并且控制微测装置中的流体的运动。

    LOW ELASTICITY FILMS FOR MICROFLUIDIC USE
    5.
    发明公开
    LOW ELASTICITY FILMS FOR MICROFLUIDIC USE 审中-公开
    FILME MIT GERINGEREELASTIZITÄTZUR MIKROFLUIDISCHEN VERWENDUNG

    公开(公告)号：EP2934751A4

    公开(公告)日：2016-11-16

    申请号：EP13865758

    申请日：2013-12-20

    Applicant: MICRONICS INC

    Inventor： SPRAGUE ISAAC ,  KAY JUSTIN L ,  BRAGD MATTHEW SCOTT ,  BATTRELL C FREDERICK

    IPC: B01L3/00

    CPC classification number: B01L3/502707 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2400/06 ,  F04B19/006 ,  F04B43/043 ,  F16K99/0015 ,  F16K99/0055 ,  F16K2099/0084

    Abstract: Microfluidic circuit elements, such as a microvalve, micropump or microvent, formed of a microcavity divided by a diaphragm web into a first subcavity bounded by a first internal wall and a second subcavity bounded by a second internal wall, where the diaphragm web is characterized as a thin film having a first state contacting the first internal wall and a second state contacting the second internal wall and exhibiting essentially no elasticity in moving between the first state and the second state, the thin film web having been stretched beyond its yield point before or during use are provided. The disclosed elements enable faster and more efficient cycling of the diaphragm in the microcavity and increases the diaphragm surface area. In a preferred embodiment, the microfluidic circuit element is pneumatically driven and controls the motion of fluids in a microassay device.

    Abstract translation: 微流体电路元件，例如微阀，微型泵或微量元件，由微腔分隔成由第一内壁限定的第一子空腔和由第二内壁限定的第二子腔，微腔由隔膜腹板分隔，其中隔膜腹板的特征在于 具有接触第一内壁的第一状态的薄膜和接触第二内壁的第二状态，并且在第一状态和第二状态之间基本上没有弹性移动，薄膜纤维网已被拉伸超过其屈服点之前或 在使用期间提供。 所公开的元件使得隔膜在微腔中更快且更有效地循环并增加隔膜表面积。 在优选实施例中，微流体电路元件被气动驱动并且控制微量测量装置中的流体的运动。

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