公开(公告)号：IT1188550B

公开(公告)日：1988-01-14

申请号：IT1933886

申请日：1986-02-07

Applicant: SCLAVO SPA

Inventor： TAGLIABUE ALDO ,  ANTONI GUIDO ,  PRESENTINI RIVO ,  BORASCHI DIAN

IPC: A61K38/00 ,  C07K14/52 ,  A61K39/39 ,  A61P37/00 ,  C07K7/06 ,  C07K14/54 ,  C07K14/545 ,  A61K

Abstract: Synthetic peptide with human interleukin 1 acti­vity, which peptide can be used as a stimulant of the immune functions and can be defined by the general formula:    Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-X      (I)where:Val = L-valine; Gln = L-glutamine; Gly = glycine; Glu = L-glutamic acid; Ser = L-serine; Asn = L-asparagine; Asp = L-aspartic acid; Lys = L-lysine; X = cysteine (Cys), OH, NH₂, a benzyl ester or an alkyl ester group having a number of carbon atoms from 1 to 7.