公开(公告)号：JP2002241387A

公开(公告)日：2002-08-28

申请号：JP2001378680

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for the synthesis, screening and characterization of an organic metal compound and a catalyst (for example, a homogeneous catalyst). SOLUTION: A method for producing an array of an activated metal ligand compound comprises (a) a process for forming the first metal ligand compound in the first region on a substrate and forming the second metal ligand compound different from the first metal ligand compound in the second region on the substrate to form the arrays of the metal ligand compounds in the prescribed regions of the substrate at a space, and (b) a process for supplying one or more activating substances comprising ionizing agents or alkylating agents to the first region and the second region.

公开(公告)号：JP2002241388A

公开(公告)日：2002-08-28

申请号：JP2001378681

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for the synthesis, screening and characterization of an organic metal compound and a catalyst (for example, a homogeneous catalyst). SOLUTION: A method for producing an array of a carried metal ligand compound, which enables the measurement of at least one change of a ligand core, the identity of the substituent of the ligand core, the electric charge of a metal ion, a counter ion, an activating substance, reaction conditions, a solvent, additives, and a linker, comprises disposing the first metal ligand compound and the second metal ligand compound different from the first metal ligand compound, carried on a carrier different from the substrate, thus forming the combinatorial array of the metal ligand compounds carried at a space.

公开(公告)号：JP2002241319A

公开(公告)日：2002-08-28

申请号：JP2001378679

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for synthesizing a library of an organometallic material and screening the library in regard to catalytic activity. SOLUTION: This method for producing an array of a metal-ligand compound and screening comprises (a) synthesizing an array of spatially separated ligands, (b) preparing the array of metal-ligand compounds by feeding a suitable metal precursor to each of the elements of the array of ligands, (c) selectively activating the array of metal-ligand compounds with a suitable co-catalyst, (d) modifying the array of metal-ligand compounds with a third component, (e) screening the array of metal-ligand compounds in regard to useful characteristics by using a parallel or rapid serial screening method selected from a group consisting of an optical imaging, an optical spectroscopy, a mass spectroscopy, a chromatography, a sonic imaging, a sonic spectroscopy, an infrared imaging and an infrared spectroscopy.

公开(公告)号：AT210620T

公开(公告)日：2001-12-15

申请号：AT99203631

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY W ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：DE69708331T3

公开(公告)日：2010-10-28

申请号：DE69708331

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY W ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  C07B61/00 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

公开(公告)号：CA2261305C

公开(公告)日：2006-03-21

申请号：CA2261305

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  POWERS TIMOTHY ,  MURPHY VINCE

IPC: B01J23/22 ,  C07F17/00 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: The present invention relates, Inter alia, to methodologies for the synthesi s, screening and characterization of organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (e.g., homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：DE69707294T2

公开(公告)日：2002-05-02

申请号：DE69707294

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：AU7801698A

公开(公告)日：1998-12-30

申请号：AU7801698

申请日：1998-05-28

Applicant: SYMYX TECHNOLOGIES INC

Inventor： BOUSSIE THOMAS ,  HALL KEITH A ,  LAPOINTE ANNE M ,  MURPHY VINCE ,  POWERS TIMOTHY ,  BEEK JOHANNES A M VAN

IPC: B01J19/00 ,  C07B61/00 ,  C07F19/00

公开(公告)号：DK0923590T3

公开(公告)日：2002-01-28

申请号：DK97934335

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：DE69708928D1

公开(公告)日：2002-01-17

申请号：DE69708928

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY W ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.