公开(公告)号：JP2002241387A

公开(公告)日：2002-08-28

申请号：JP2001378680

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for the synthesis, screening and characterization of an organic metal compound and a catalyst (for example, a homogeneous catalyst). SOLUTION: A method for producing an array of an activated metal ligand compound comprises (a) a process for forming the first metal ligand compound in the first region on a substrate and forming the second metal ligand compound different from the first metal ligand compound in the second region on the substrate to form the arrays of the metal ligand compounds in the prescribed regions of the substrate at a space, and (b) a process for supplying one or more activating substances comprising ionizing agents or alkylating agents to the first region and the second region.

公开(公告)号：JP2002241388A

公开(公告)日：2002-08-28

申请号：JP2001378681

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for the synthesis, screening and characterization of an organic metal compound and a catalyst (for example, a homogeneous catalyst). SOLUTION: A method for producing an array of a carried metal ligand compound, which enables the measurement of at least one change of a ligand core, the identity of the substituent of the ligand core, the electric charge of a metal ion, a counter ion, an activating substance, reaction conditions, a solvent, additives, and a linker, comprises disposing the first metal ligand compound and the second metal ligand compound different from the first metal ligand compound, carried on a carrier different from the substrate, thus forming the combinatorial array of the metal ligand compounds carried at a space.

公开(公告)号：JP2002316042A

公开(公告)日：2002-10-29

申请号：JP2002019230

申请日：2002-01-28

Applicant: SYMYX TECHNOLOGIES INC

Inventor： DALES G CAMERON ,  DIAMOND GARY M ,  FRANK TREVOR G ,  FREITAG CHRISTOPHER J ,  HIGASHIHARA KENNETH S ,  MURPHY VINCE ,  TROTH JONAH R ,  CHANDLER WILLIAM H JR ,  HUFFMAN DAVE

IPC: B01J19/26 ,  B01F7/00 ,  B01F7/16 ,  B01F13/06 ,  B01F13/08 ,  B01F15/00 ,  B01J19/00 ,  B01L3/00 ,  B01L7/00 ,  B25J9/02 ,  C40B40/14 ,  C40B40/18 ,  C40B60/00 ,  C40B60/14 ,  F28F27/00 ,  G01K13/00 ,  G01N1/22 ,  G01N21/25 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To provide a parallel reactor system suitable for the handling of fluid substances containing slurry substance and to provide a method concerning the same. SOLUTION: The parallel reactor system is provided with a reactor 9, a vessel to be placed in the reactor and holding a reaction mixture and a cannula for introducing fluid reaction substances to the vessel. A robot system 23 enables the operation of inserting the cannula into a cannula path in the reactor 9 for conveying the reactant containing the slurry to a corresponding vessel and pulling off the cannula from the cannula path after the conveyance. The related method and the cannula design are also disclosed.

公开(公告)号：JP2002241319A

公开(公告)日：2002-08-28

申请号：JP2001378679

申请日：2001-12-12

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG W HENRY ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BUSHY THOMAS ,  TURNER HOWARD ,  VAN BEEK JOHANNES A M ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F4/70 ,  C08F10/00 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: PROBLEM TO BE SOLVED: To provide a method for synthesizing a library of an organometallic material and screening the library in regard to catalytic activity. SOLUTION: This method for producing an array of a metal-ligand compound and screening comprises (a) synthesizing an array of spatially separated ligands, (b) preparing the array of metal-ligand compounds by feeding a suitable metal precursor to each of the elements of the array of ligands, (c) selectively activating the array of metal-ligand compounds with a suitable co-catalyst, (d) modifying the array of metal-ligand compounds with a third component, (e) screening the array of metal-ligand compounds in regard to useful characteristics by using a parallel or rapid serial screening method selected from a group consisting of an optical imaging, an optical spectroscopy, a mass spectroscopy, a chromatography, a sonic imaging, a sonic spectroscopy, an infrared imaging and an infrared spectroscopy.

公开(公告)号：BRPI0620665A2

公开(公告)日：2011-11-22

申请号：BRPI0620665

申请日：2006-12-08

Applicant: DOW GLOBAL TECHNOLOGIES INC ,  SYMYX TECHNOLOGIES INC

Inventor： KLOSIN JERZY ,  ACKERMAN LILY ,  BEI XIAOHONG ,  DIAMOND GARY M ,  LONGMIRE JAMES ,  MURPHY VINCE ,  NAVA-SALGADO VICTOR ,  SHOEMAKER JAMES A W

IPC: B01J31/22 ,  C08F2/04 ,  C08F4/24 ,  C08L25/06

公开(公告)号：AU6701601A

公开(公告)日：2002-01-02

申请号：AU6701601

申请日：2001-06-18

Applicant: SYMYX TECHNOLOGIES INC

Inventor： DIAMOND GARY M ,  GOH CHRISTOPHER ,  LECLERC MARGARETE K ,  MURPHY VINCE ,  TURNER HOWARD W

IPC: C07B61/00 ,  C08F4/60 ,  C08F4/659 ,  C08F110/14 ,  C08F210/16

Abstract: A method is disclosed for screening potential catalysts for polymerization performance. The method includes the steps of reacting a potential catalyst with at least a first monomer under polymerization conditions, determining the polymerization performance of the catalyst with the at least first monomer, and using the determination as a predictor for the polymerization performance of the catalyst for at least a second monomer, wherein the first and second monomers are different from each other and the first monomer is an olefin other than ethylene. The method provides a useful, concrete and tangible result that has particular value for identifying appropriate catalysts for olefin polymerization and copolymerization.

公开(公告)号：AT210620T

公开(公告)日：2001-12-15

申请号：AT99203631

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY W ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：DE60211760D1

公开(公告)日：2006-07-06

申请号：DE60211760

申请日：2002-01-21

Applicant: SYMYX TECHNOLOGIES INC

Inventor： DALES G CAMERON ,  TROTH JONAH R ,  HIGASHIHARA KENNETH S ,  DIAMOND GARY ,  MURPHY VINCE ,  CHANDLER WILLIAM H JR ,  FRANK TREVOR G ,  FREITAG J CHRISTOPHER ,  HUFFMAN DAVE

IPC: B01J19/00 ,  B01J19/26 ,  B01F7/00 ,  B01F7/16 ,  B01F13/06 ,  B01F13/08 ,  B01F15/00 ,  B01L3/00 ,  B01L7/00 ,  B25J9/02 ,  C40B40/14 ,  C40B40/18 ,  C40B60/00 ,  C40B60/14 ,  F28F27/00 ,  G01K13/00 ,  G01N1/22 ,  G01N21/25 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

Abstract: A method of preparing and delivering a slurry into a series of vessels in a reactor, said method comprising: (1) mixing a particulate solid material and a liquid dispersing medium and agitating the mixture to form a substantially homogeneous first slurry in which said particulate solid material is suspended in the liquid; (2) aspirating said first slurry into a cannula carried by a robot system while the slurry is substantially homogeneous; (3) operating the robot system to insert the cannula into the reactor;(4) delivering the slurry from the cannula into the vessel while the cannula is in said reactor; and (5) repeating (2)-(4) for a second vessel with said first slurry or repeating (2)-(4) for a second vessel with a second slurry.

公开(公告)号：CA2369222C

公开(公告)日：2006-06-20

申请号：CA2369222

申请日：2002-01-23

Applicant: SYMYX TECHNOLOGIES INC

Inventor： FREITAG J CHRISTOPHER ,  DALES G CAMERON ,  HIGASHIHARA KENNETH S ,  FRANK TREVOR G ,  TROTH JONAH R ,  DIAMOND GARY M ,  HUFFMAN DAVE ,  CHANDLER WILLIAM H JR ,  MURPHY VINCE

IPC: B01J19/00 ,  B01J19/26 ,  B01F7/00 ,  B01F7/16 ,  B01F13/06 ,  B01F13/08 ,  B01F15/00 ,  B01J8/14 ,  B01L3/00 ,  B01L7/00 ,  B08B3/00 ,  B25J9/02 ,  B25J11/00 ,  C40B40/14 ,  C40B40/18 ,  C40B60/00 ,  C40B60/14 ,  F28F27/00 ,  G01K13/00 ,  G01N1/22 ,  G01N21/25 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods and cannula designs are also disclosed.

公开(公告)号：DE69709179T2

公开(公告)日：2002-07-18

申请号：DE69709179

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WEINBERG HENRY W ,  MCFARLAND ERIC ,  GOLDWASSER ISY ,  BOUSSIE THOMAS ,  TURNER HOWARD ,  BEEK JOHANNES A M VAN ,  MURPHY VINCE ,  POWERS TIMOTHY

IPC: B01J23/22 ,  B01J19/00 ,  B01J31/16 ,  B01J31/22 ,  B01J37/00 ,  C07B61/00 ,  C07C249/02 ,  C07C251/08 ,  C07C251/16 ,  C07D213/53 ,  C07F15/00 ,  C07F15/04 ,  C07F17/00 ,  C07F19/00 ,  C08F4/00 ,  C08F4/60 ,  C08F4/70 ,  C08F10/00 ,  C08F110/02 ,  C40B40/04 ,  C40B40/18 ,  C40B50/00 ,  C40B60/14 ,  G01N1/10 ,  G01N21/64 ,  G01N29/24 ,  G01N29/34 ,  G01N29/44

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.