公开(公告)号：WO0168248A3

公开(公告)日：2002-01-31

申请号：PCT/US0140287

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  ARGYROPOULOS JOHN NICHOLAS ,  PHILLIPS AILENE GARDNER ,  ROESCH BRIAN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MIN MAX ,  MAHER JOHN MICHAEL ,  BRYANT DAVID ROBERT

IPC: C07B63/00 ,  C07C45/50 ,  B01D11/04 ,  C07F9/02

CPC classification number: C07B63/00 ,  C07C45/50 ,  Y02P20/582 ,  C07C47/02

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more polar reaction solvents and one or more nonpolar reaction solvents, wherein said process comprises (1) subjecting said reaction product fluid to fractional countercurrent extraction with at least two immiscible extraction solvents, said at least two immiscible extraction solvents comprising at least one polar extraction solvent and at least one nonpolar extraction solvent, to obtain a polar phase comprising said metal-organophosphorus ligand complex catalyst, said optionally free organophosphorus ligand, said one or more polar reaction solvents and said at least one polar extraction solvent and a nonpolar phase comprising said one or more products, said one or more nonpolar reaction solvents and said at least one nonpolar extraction solvent, and (2) recovering said nonpolar phase from said polar phase; wherein (i) the organophosphorus ligand has a partition coefficient Kp1 defined herein between the polar phase and the nonpolar phase of greater than about 5, and (ii) the one or more products have a partition coefficient Kp2 defined herein between the polar phase and the nonpolar phase of less than about 2.0.

Abstract translation: 本发明涉及用于从反应产物流体中分离一种或多种产物的方法，其包括金属 - 有机磷配体配合物催化剂，任选的游离有机磷配体，所述一种或多种产物，一种或多种极性反应溶剂和一种或多种非极性反应溶剂 其中所述方法包括（1）使所述反应产物流体与至少两种不混溶的萃取溶剂进行分数逆流萃取，所述至少两种不混溶的萃取溶剂包含至少一种极性萃取溶剂和至少一种非极性萃取溶剂，以获得 所述极性相包含所述金属 - 有机磷配体配合物催化剂，所述任选游离的有机磷配体，所述一种或多种极性反应溶剂和所述至少一种极性提取溶剂和包含所述一种或多种产物的非极性相，所述一种或多种非极性反应溶剂 并表示至少一种非极性萃取溶剂，和（ 2）从所述极性相中回收所述非极性相; 其中（i）有机磷配体在极性相和非极性相之间定义的分配系数Kp1大于约5，和（ii）一种或多种产物在极性相和极性相之间具有限定的分配系数Kp2 非极性相小于约2.0。

公开(公告)号：WO0168249A3

公开(公告)日：2002-03-28

申请号：PCT/US0108156

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： ARGYROPOULOS JOHN NICHOLAS ,  KANEL JEFFREY SCOTT ,  TULCHINSKY MICHAEL LEO ,  MILLER DAVID JAMES ,  MORRISON DONALD LEE ,  FOLEY PAUL ,  BRYANT DAVID ROBERT ,  PHILLIPS AILENE GARDNER ,  ROESCH BRIAN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MAY MIN ,  MAHER JOHN MICHAEL

IPC: C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C47/02 ,  C07C47/19 ,  C07F9/02

CPC classification number: C07C45/50 ,  C07B63/00 ,  Y02P20/582 ,  C07C47/02

Abstract: This invention relates to a process for separating one or moer organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphous ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more polar solvents and one or more nonpolar solvent by phase separation wherein (i) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Efl which is a value greater than about 2.5, (ii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.

Abstract translation: 本发明涉及一种从连续生成的反应产物流体中分离一种或更多的有机磷配体降解产物，一种或多种反应副产物和一种或多种产物的方法，所述反应产物流体包含一种或多种未反应的反应物，金属有机磷配体络合物催化剂， 有机磷配体，所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，一种或多种极性溶剂和一种或多种非极性溶剂通过相分离，其中（i）极性相的选择性为 有机磷配体相对于一种或多种产物的分配系数比Efl表示为大于约2.5的值，（ii）极性相对于有机磷配体相对于一种或多种有机磷配体的选择性 降解产物由大于的值的分配系数比Ef2表示 约为2.5，（iii）相对于一种或多种反应副产物，极性相对有机磷配体的选择性由分配系数比Ef3表示，该分配系数比Ef3是大于约2.5的值。

公开(公告)号：WO0168250A3

公开(公告)日：2002-01-31

申请号：PCT/US0108173

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： ARGYROPOULOS JOHN NICHOLAS ,  KANEL JEFFREY SCOTT ,  TULCHINSKY MICHAEL LEO ,  MILLER DAVID JAMES ,  MORRISON DONALD LEE ,  FOLEY PAUL ,  BRYANT DAVID ROBERT ,  PHILLIPS AILENE GARDNER ,  ROESCH BRIAN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MAX MIN ,  MAHER JOHN MICHAEL

IPC: B01D11/04 ,  B01J23/46 ,  B01J31/18 ,  B01J31/24 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/80 ,  C07C47/19 ,  C07F9/02

CPC classification number: C07C45/50 ,  C07B63/00 ,  Y02P20/582 ,  C07C47/02

Abstract: This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more nonpolar solvents and one or more polar solvents by phase separation wherein (i) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1 which is a value greater than about 2.5, (ii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more organosphosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.

Abstract translation: 本发明涉及从连续生成的反应产物流体中分离一种或多种有机磷配体降解产物，一种或多种反应副产物和一种或多种产物，所述反应产物流体包含一种或多种未反应的反应物，金属 - 有机磷配体络合物催化剂， 有机磷配体，所述一种或多种有机磷配体降解产物，所述一种或多种反应副产物，所述一种或多种产物，一种或多种非极性溶剂和一种或多种极性溶剂通过相分离，其中（i）非极性相的选择性为 相对于一种或多种产物的有机磷配体由分配系数比Ef1表示，分配系数比Ef1是大于约2.5的值，（ii）非极性相对有机磷配体相对于一种或多种有机磷配体的选择性 降解产物由分配系数比Ef2表示，分配系数比Ef2是值gre 高于约2.5，以及（iii）非极性相对于一种或多种反应副产物的有机磷配体的选择性由大于约2.5的值的分配系数比Ef3表示。

公开(公告)号：WO0168247A8

公开(公告)日：2004-06-24

申请号：PCT/US0140286

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  BRYANT DAVID ROBERT ,  ROESCH BRIAN MICHAEL ,  PHILLIPS AILENE GARDNER

IPC: B01D11/04 ,  B01J31/00 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/78 ,  C07C47/02 ,  C07F9/02 ,  C07C29/16 ,  C07C29/74 ,  C07C253/30 ,  C07C253/32

CPC classification number: B01J31/4015 ,  B01J31/1845 ,  B01J31/185 ,  B01J31/24 ,  B01J31/4046 ,  B01J31/4053 ,  B01J2231/32 ,  B01J2231/321 ,  B01J2231/50 ,  B01J2231/641 ,  B01J2531/16 ,  B01J2531/17 ,  B01J2531/18 ,  B01J2531/60 ,  B01J2531/80 ,  B01J2531/822 ,  C07B63/00 ,  C07F9/025 ,  Y02P20/582 ,  Y02P20/584

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar reaction solvents and one or more polar reaction solvents, in which said reaction product fluid exhibits phase behavior depicted by Fig. 1, wherein said process comprises (1) supplying said reaction product fluid from a reaction zone to a separation zone, (2) controlling concentration of said one or more nonpolar reaction solvents and said one or more polar reaction solvents, temperature and pressure in said separation zone sufficient to obtain by phase separation two immiscible liquid phases depicted by regions 2, 4 and 6 of Fig. 1 comprising a polar phase and a nonpolar phase and to prevent or minimize formation of three immiscible liquid phases depicted by region 5 of Fig. 1 and one homogeneous liquid phase depicted by regions 1, 3 and 7 of Fig. 1, and (3) recovering said polar phase from said nonpolar phase or said nonpolar phase from said polar phase.

Abstract translation: 本发明涉及一种从反应产物流体中分离一种或多种产物的方法，其包括金属 - 有机磷配体配合物催化剂，任选的游离有机磷配体，所述一种或多种产物，一种或多种非极性反应溶剂和一种或多种极性反应溶剂 ，其中所述反应产物流体表现出由图1描绘的相位行为。 1，其中所述方法包括（1）将反应产物流体从反应区供应到分离区，（2）控制所述一种或多种非极性反应溶剂和所述一种或多种极性反应溶剂的浓度，所述的一种或多种极性反应溶剂的温度和压力 分离区足以通过相分离获得图2的区域2,4和6所示的两个不混溶的液相。 1包括极性相和非极性相，并且防止或最小化由图1的区域5描绘的三个不混溶的液相的形成。 1和图1的区域1,3和7所示的一个均匀液相。 1，和（3）从所述极性相从所述非极性相或所述非极性相回收所述极性相。

公开(公告)号：WO0168251A3

公开(公告)日：2002-01-31

申请号：PCT/US0108180

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  ARGYROPOULOS JOHN NICHOLAS ,  PHILLIPS AILENE GARDNER ,  ROESCH BRAIN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MIN MAX ,  MAHER JOHN MICHAEL ,  BRYANT DAVID ROBERT

IPC: C07B63/00 ,  C07C45/50 ,  B01D11/04 ,  C07F9/02

CPC classification number: C07C45/50 ,  C07B63/00 ,  Y02P20/582 ,  C07C47/02

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar reaction solvents and one or more polar reaction solvents, wherein said process comprises (1) subjecting said reaction product fluid to fractional countercurrent extraction with at least two immiscible extraction solvents, said at least two immiscible extraction solvents comprising at least one nonpolar extraction solvent and at least one polar extraction solvent, to obtain a nonpolar phase comprising said metal-organophosphorus ligand complex catalyst, said optionally free organophosphorus ligand, said one or more nonpolar reaction solvents and said at least one nonpolar extraction solvent and a polar phase comprising said one or more products, said one or more polar reaction solvents and said at least one polar extraction solvent, and (2) recovering said polar phase from said nonpolar phase; wherein (i) the organophosphorus ligand has a partition coefficient Kp1 defined herein between the nonpolar phase and the polar phase of greater than about 5, and (ii) the one or more products have a partition coefficient Kp2 defined herein between the nonpolar phase and the polar phase of less than about 2.0.

Abstract translation: 本发明涉及从反应产物流体中分离一种或多种产物的方法，其包括金属 - 有机磷配体配合物催化剂，任选的游离有机磷配体，所述一种或多种产物，一种或多种非极性反应溶剂和一种或多种极性反应溶剂 其中所述方法包括（1）使所述反应产物流体用至少两种不混溶的萃取溶剂进行分数逆流萃取，所述至少两种不混溶的萃取溶剂包含至少一种非极性萃取溶剂和至少一种极性提取溶剂，以获得 所述非极性相包含所述金属 - 有机磷配体配合物催化剂，所述任选游离的有机磷配体，所述一种或多种非极性反应溶剂和所述至少一种非极性萃取溶剂和包含所述一种或多种产物的极性相，所述一种或多种极性反应溶剂 并表示至少一种极性提取溶剂，和（ 2）从所述非极性相中回收所述极性相; 其中（i）有机磷配体在非极性相和极性相之间定义的分配系数Kp1大于约5，并且（ii）一种或多种产物在非极性相和非极性相之间具有本文定义的分配系数Kp2 极性相小于约2.0。

公开(公告)号：WO0168247A2

公开(公告)日：2001-09-20

申请号：PCT/US0140286

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  BRYANT DAVID ROBERT ,  ROESCH BRIAN MICHAEL ,  PHILLIPS AILENE GARDNER

IPC: B01D11/04 ,  B01J31/00 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/78 ,  C07C47/02 ,  C07F9/02

CPC classification number: B01J31/4015 ,  B01J31/1845 ,  B01J31/185 ,  B01J31/24 ,  B01J31/4046 ,  B01J31/4053 ,  B01J2231/32 ,  B01J2231/321 ,  B01J2231/50 ,  B01J2231/641 ,  B01J2531/16 ,  B01J2531/17 ,  B01J2531/18 ,  B01J2531/60 ,  B01J2531/80 ,  B01J2531/822 ,  C07B63/00 ,  C07F9/025 ,  Y02P20/582 ,  Y02P20/584

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar reaction solvents and one or more polar reaction solvents, in which said reaction product fluid exhibits phase behavior depicted by Fig. 1, wherein said process comprises (1) supplying said reaction product fluid from a reaction zone to a separation zone, (2) controlling concentration of said one or more nonpolar reaction solvents and said one or more polar reaction solvents, temperature and pressure in said separation zone sufficient to obtain by phase separation two immiscible liquid phases depicted by regions 2, 4 and 6 of Fig. 1 comprising a polar phase and a nonpolar phase and to prevent or minimize formation of three immiscible liquid phases depicted by region 5 of Fig. 1 and one homogeneous liquid phase depicted by regions 1, 3 and 7 of Fig. 1, and (3) recovering said polar phase from said nonpolar phase or said nonpolar phase from said polar phase.

Abstract translation: 本发明涉及一种从反应产物流体中分离一种或多种产物的方法，其包括金属 - 有机磷配体配合物催化剂，任选的游离有机磷配体，所述一种或多种产物，一种或多种非极性反应溶剂和一种或多种极性反应溶剂 ，其中所述反应产物流体表现出由图1描绘的相位行为。 1，其中所述方法包括（1）将反应产物流体从反应区供应到分离区，（2）控制所述一种或多种非极性反应溶剂和所述一种或多种极性反应溶剂的浓度，所述的一种或多种极性反应溶剂的温度和压力 分离区足以通过相分离获得图2的区域2,4和6所示的两个不混溶的液相。 1包括极性相和非极性相，并且防止或最小化由图1的区域5描绘的三个不混溶的液相的形成。 1和图1的区域1,3和7所示的一个均匀液相。 1，和（3）从所述极性相从所述非极性相或所述非极性相回收所述极性相。

公开(公告)号：AT314335T

公开(公告)日：2006-01-15

申请号：AT01922386

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： ARGYROPOULOS JOHN NICHOLAS ,  KANEL JEFFREY SCOTT ,  TULCHINSKY MICHAEL LEO ,  MILLER DAVID JAMES ,  MORRISON DONALD LEE ,  FOLEY PAUL ,  BRYANT DAVID ROBERT ,  PHILLIPS AILENE GARDNER ,  ROESCH BRIAN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MAX MIN ,  MAHER JOHN MICHAEL

IPC: C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C47/02 ,  C07C47/19 ,  C07F9/02

Abstract: This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more polar solvents and one or more nonpolar solvents by phase separation wherein (i) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1 which is a value greater than about 2.5, (ii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the polar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.

公开(公告)号：BR0109195A

公开(公告)日：2004-07-06

申请号：BR0109195

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  BRYANT DAVID ROBERT ,  ROESCH BRIAN MICHAEL ,  PHILLIPS AILENE GARDNER

IPC: B01D11/04 ,  B01J31/00 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/78 ,  C07C47/02 ,  C07F9/02

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar reaction solvents and one or more polar reaction solvents, in which said reaction product fluid exhibits phase behavior depicted by FIG. 1, wherein said process comprises (1) supplying said reaction product fluid from a reaction zone to a separation zone, (2) controlling concentration of said one or more nonpolar reaction solvents and said one or more polar reaction solvents, temperature and pressure in said separation zone sufficient to obtain by phase separation two immiscible liquid phases depicted by regions 2, 4 and 6 of FIG. 1 comprising a polar phase and a nonpolar phase and to prevent or minimize formation of three immiscible liquid phases depicted by region 5 of FIG. 1 and one homogeneous liquid phase depicted by regions 1, 3 and 7 of FIG. 1, and (3) recovering said polar phase from said nonpolar phase or said nonpolar phase from said polar phase.

公开(公告)号：BR0109216A

公开(公告)日：2002-12-03

申请号：BR0109216

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： ARGYROPOULOS JOHN NICHOLAS ,  KANEL JEFFREY SCOTT ,  TULCHINSKY MICHAEL LEO ,  MILLER DAVID JAMES ,  MORRISON DONALD LEE ,  FOLEY PAUL ,  BRYANT DAVID ROBERT ,  PHILLIPS AILENE GARDNER ,  ROESCH BRIAN MICHAEL ,  BRIGGS JOHN ROBERT ,  LEE MAX MIN ,  MAHER JOHN MICHAEL

IPC: B01D11/04 ,  B01J23/46 ,  B01J31/18 ,  B01J31/24 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/80 ,  C07C47/19 ,  C07F9/02 ,  B01J31/00

Abstract: This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more organophosphorus ligand degradation products, said one or more reaction byproducts, said one or more products, one or more nonpolar solvents and one or more polar solvents by phase separation wherein (i) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more products is expressed by a partition coefficient ratio Ef1which is a value greater than about 2.5, (ii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more organophosphorus ligand degradation products is expressed by a partition coefficient ratio Ef2 which is a value greater than about 2.5, and (iii) the selectivity of the nonpolar phase for the organophosphorus ligand with respect to the one or more reaction byproducts is expressed by a partition coefficient ratio Ef3 which is a value greater than about 2.5.

公开(公告)号：AU5385001A

公开(公告)日：2001-09-24

申请号：AU5385001

申请日：2001-03-14

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： KANEL JEFFREY SCOTT ,  BRYANT DAVID ROBERT ,  ROESCH BRIAN MICHAEL ,  PHILLIPS AILENE GARDNER

IPC: B01D11/04 ,  B01J31/00 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07B63/00 ,  C07C45/50 ,  C07C45/78 ,  C07C47/02 ,  C07F9/02

Abstract: This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar reaction solvents and one or more polar reaction solvents, in which said reaction product fluid exhibits phase behavior depicted by FIG. 1, wherein said process comprises (1) supplying said reaction product fluid from a reaction zone to a separation zone, (2) controlling concentration of said one or more nonpolar reaction solvents and said one or more polar reaction solvents, temperature and pressure in said separation zone sufficient to obtain by phase separation two immiscible liquid phases depicted by regions 2, 4 and 6 of FIG. 1 comprising a polar phase and a nonpolar phase and to prevent or minimize formation of three immiscible liquid phases depicted by region 5 of FIG. 1 and one homogeneous liquid phase depicted by regions 1, 3 and 7 of FIG. 1, and (3) recovering said polar phase from said nonpolar phase or said nonpolar phase from said polar phase.