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公开(公告)号：WO2013136193A8
公开(公告)日：2014-05-08
申请号：PCT/IB2013001179
申请日：2013-03-14
Applicant: UNIV HEALTH NETWORK , TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
CPC classification number: C07K14/70503 , A61K38/1709 , A61K38/1774 , C07K14/705 , C07K2319/02 , C07K2319/30
Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
Abstract translation: 本发明还涉及用于调节Toso蛋白质活性的方法和组合物。 本发明还包括使用包含可溶性Toso蛋白的组合物治疗与炎症，自身免疫病和癌症相关的病症。
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公开(公告)号：WO2013136193A3
公开(公告)日：2014-01-16
申请号：PCT/IB2013001179
申请日：2013-03-14
Applicant: UNIV HEALTH NETWORK , TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
CPC classification number: C07K14/70503 , A61K38/1709 , A61K38/1774 , C07K14/705 , C07K2319/02 , C07K2319/30
Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
Abstract translation: 本发明进一步涉及用于调节Toso蛋白活性的方法和组合物。 本发明还包括使用包括可溶性Toso蛋白的组合物治疗与炎症，自身免疫疾病和癌症相关的病症。
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公开(公告)号：AU2019204594A1
公开(公告)日：2019-07-18
申请号：AU2019204594
申请日：2019-06-28
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: METHODS AND COMPOSITIONS FOR MODULATING TOSO ACTIVITY The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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公开(公告)号：AU2017272172B2
公开(公告)日：2019-04-04
申请号：AU2017272172
申请日：2017-12-05
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: METHODS AND COMPOSITIONS FOR MODULATING TOSO ACTIVITY The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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公开(公告)号：AU6677000A
公开(公告)日：2001-03-26
申请号：AU6677000
申请日：2000-08-23
Applicant: UNIV HEALTH NETWORK
Inventor： OHASHI PAMELA S
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Patent Agency Ranking
公开(公告)号：AU2019204594B2
公开(公告)日：2021-05-06
申请号：AU2019204594
申请日：2019-06-28
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: METHODS AND COMPOSITIONS FOR MODULATING TOSO ACTIVITY The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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公开(公告)号：AU2013234046A1
公开(公告)日：2014-10-09
申请号：AU2013234046
申请日：2013-03-14
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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公开(公告)号：CA3032249A1
公开(公告)日：2018-02-22
申请号：CA3032249
申请日：2017-08-17
Applicant: UNIV HEALTH NETWORK
Inventor： NGUYEN THUY-LINH , OHASHI PAMELA S , CROME SARAH
IPC: A61K39/395 , A61P35/00 , C07K16/28 , C07K16/30 , G01N33/48
Abstract: There is described herein methods for improving tumor infiltrating lymphocyte (TIL) therapy by limiting the effect of innate lymphoid cells (ILCs) thereon. For example, in an aspect, there is provided a method of treating cancer in a patient in need thereof, comprising inhibiting the suppressive effect of CD56+CD3- innate lymphoid cells (ILCs) on tumor infiltrating lymphocyte (TIL) propagation or expansion.
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公开(公告)号：AU2017272172A1
公开(公告)日：2017-12-21
申请号：AU2017272172
申请日：2017-12-05
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: METHODS AND COMPOSITIONS FOR MODULATING TOSO ACTIVITY The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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公开(公告)号：AU2013234046B2
公开(公告)日：2017-09-07
申请号：AU2013234046
申请日：2013-03-14
Applicant: UNIV HEALTH NETWORK
Inventor： TUSCHE MICHAEL W , MAK TAK W , OHASHI PAMELA S , LANG PHILIPP , LANG KARL , BRENNER DIRK , LIN GLORIA
Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.
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