Patent search ap:("VERTEX PHARMA") AND inv:"SONG ZHENGTIAN" Page 1

1.

发明专利
SOLID FORMS OF 4-(5-(4-FLUOROPHENYL)-6-TETRAHYDRO-2H-PYRAN-4-YL)- 1,5-DIHYDROPYRROLO[2,3-F]INDAZOL-7-YL)BENZOIC ACID 未知

公开(公告)号：AU2021381509A1

公开(公告)日：2023-06-22

申请号：AU2021381509

申请日：2021-11-17

Applicant: VERTEX PHARMA

Inventor： SHI YI , LAI MEI-HSIU , MEDEK ALES , HU KAN-NIAN , SONG ZHENGTIAN , TORRICO GUZMAN ELISA , SOKOLOWSKY KATHLEEN , GIROUX SIMON , LIU SIYING , OVERHOFF KIRK , RODAY SETU , SAWANT RUPA , SPOSATO MARISA

IPC: A61P1/16 , A61K31/416 , A61K31/4162 , A61P11/00 , C07D487/04

Abstract: Solid forms of 4-(5-(4-fluorophenyl)-6-(tetrahydro-2H-pyran-4-yl)-1,5-dihydropyrrolo[2,3-f]indazol-7-yl)benzoic acid (Compound 1) capable of modulating alpha-1 antitrypsin (AAT) activity and methods of treating alpha-1 antitrypsin deficiency (AATD) by administering one or more such forms, and methods of using and preparing the same for treatment of alpha-1 antitrypsin deficiency (AATD).

2.

发明专利
FORMAS SÓLIDAS DE ÁCIDO 4-(5-(4-FLUOROFENIL)-6-(TETRAHIDRO-2H-PIRA N-4-IL)-1,5-DIHIDROPIRROLO[2,3-F]INDAZOL-7-IL)BENZOICO. 未知

公开(公告)号：MX2023005589A

公开(公告)日：2023-07-31

申请号：MX2023005589

申请日：2021-11-17

Applicant: VERTEX PHARMA

Inventor： SHI YI , GIROUX SIMON , MEDEK ALES , RODAY SETU , SAWANT RUPA , LAI MEI-HSIU , LIU SIYING , OVERHOFF KIRK ALAN , SPOSATO MARISA , HU KAN-NIAN , SONG ZHENGTIAN , TORRICO GUZMAN ELISA A , SOKOLOWSKY KATHLEEN PAIGE

IPC: A61P1/16 , A61K31/416 , A61K31/4162 , A61P11/00 , C07D487/04

Abstract: Formas sólidas del ácido 4-(5-(4-fluorofenil)-6- (tetrahidro-2H-piran-4-il)-1,5-dihidropirrolo[2,3-f]indazol-7-il) benzoico (Compuesto 1) capaces de modular la actividad de la alfa-1 antitripsina (AAT) y métodos para tratar la deficiencia de alfa-1 antitripsina (AATD) al administrar una o más de estas formas, y métodos de uso y preparación de las mismas para el tratamiento de la deficiencia de la alfa-1 antitripsina (AATD).

3.

发明专利
SOLID FORMS OF 4-(5-(4-FLUOROPHENYL)-6-(TETRAHYDRO-2H-PYRAN-4-YL)- 1,5-DIHYDROPYRROLO[2,3-F]INDAZOL-7-YL)BENZOIC ACID 未知

公开(公告)号：CA3202071A1

公开(公告)日：2022-05-27

申请号：CA3202071

申请日：2021-11-17

Applicant: VERTEX PHARMA

Inventor： SHI YI , LAI MEI-HSIU , MEDEK ALES , HU KAN-NIAN , SONG ZHENGTIAN , TORRICO GUZMAN ELISA A , SOKOLOWSKY KATHLEEN PAIGE , GIROUX SIMON , LIU SIYING , OVERHOFF KIRK ALAN , RODAY SETU , SAWANT RUPA , SPOSATO MARISA

IPC: A61K31/416 , A61K31/4162 , A61P1/16 , A61P11/00 , C07D487/04

Abstract: Solid forms of 4-(5-(4-fluorophenyl)-6-(tetrahydro-2H-pyran-4-yl)-1,5-dihydropyrrolo[2,3-f]indazol-7-yl)benzoic acid (Compound 1) capable of modulating alpha-1 antitrypsin (AAT) activity and methods of treating alpha-1 antitrypsin deficiency (AATD) by administering one or more such forms, and methods of using and preparing the same for treatment of alpha-1 antitrypsin deficiency (AATD).

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