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公开(公告)号：US09664608B2
公开(公告)日：2017-05-30
申请号：US14464658
申请日：2014-08-20
Inventor： Wayne Frederick Reed , Michael Felix Drenski , Alex Wayne Reed
CPC classification number: G01N15/0211 , G01N21/51 , G01N21/53 , G01N33/6803 , G01N2021/4711 , G01N2021/4719 , G01N2021/4726 , G01N2021/4792 , G01N2201/0612 , G01N2201/08 , G01N2201/1224
Abstract: Simultaneous Multiple Sample Light Scattering systems and methods can be used for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces, among others, that create a polymer stress response used to characterize the polymer solution and stability.
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公开(公告)号：US20230144017A1
公开(公告)日：2023-05-11
申请号：US17951721
申请日：2022-09-23
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
Inventor： Wayne Frederick REED , Rick D. MONTGOMERY , Michael Felix DRENSKI , Aide WU
CPC classification number: G01N21/75 , B01J19/0006 , C08F20/56 , C08F2400/02 , B01J2219/002 , B01J2219/00186 , B01J2219/00231 , B01J2219/00218
Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property. The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.
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公开(公告)号：US20190128812A1
公开(公告)日：2019-05-02
申请号：US16094542
申请日：2017-04-21
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
Inventor： Wayne Frederick REED , Rick D. MONTGOMERY , Michael Felix DRENSKI , Aide WU
Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.
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4.发明申请公开(公告)号：US20190086437A1
公开(公告)日：2019-03-21
申请号：US16082818
申请日：2017-03-07
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCTIONAL FUND
Inventor： Wayne Frederick REED , Alex REED , Michael Felix DRENSKI
Abstract: Devices and methods for rapidly and incrementally or continuously, measuring rheological properties of polymers under different shear rates. The device includes a pump configured to accept a continuous stream of sample solution during an interval of time, an injector configured to inject a flow of the sample solution through two or more viscometers, and a computing and processing device configured to monitor and measure rheological properties of the solution under at least two shear rates simultaneously in the two or more viscometers.
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公开(公告)号：US10197500B2
公开(公告)日：2019-02-05
申请号：US15544176
申请日：2016-01-19
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
Inventor： Wayne Frederick Reed , Michael Felix Drenski
IPC: G01N21/75 , G01N21/27 , G01N21/84 , G01N35/00 , B01J8/00 , B01J19/00 , B01J19/18 , B01J8/22 , G01N21/19 , G01N21/21 , G01N21/23 , G01N21/33 , G01N21/35 , G01N21/47 , G01N21/64 , G01N21/65 , G01N11/08
Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.
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Patent Agency Ranking
公开(公告)号：US11532381B2
公开(公告)日：2022-12-20
申请号：US16070117
申请日：2017-01-12
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATION FUND
Inventor： Wayne Frederick Reed , Daniel J. Rees
Abstract: Method, device, and system for identifying a model-based time dependent light scattering signature that includes receiving an experimental time dependent light scattering signature comprising experimental data descriptive of an average molecular weight of protein components in a solution over time. The method further includes identifying an Ansatz for evaluating the experimental time dependent light scattering signature, the Ansatz being an initial model-based time dependent light scattering signature, the initial model-based time dependent light scattering signature identifying at least one key variable. The method also includes adjusting the at least one key variable in the initial model-based time dependent light scattering signature until a final model-based time dependent light scattering signature is identified. In some instances, the final model-based time dependent light scattering signature identifies at least one protein aggregation mechanism.
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7.发明申请公开(公告)号：US20190194360A1
公开(公告)日：2019-06-27
申请号：US16329147
申请日：2017-08-31
Inventor： Wayne Frederick REED , Michael Felix DRENSKI , Natalie LEONARDI
CPC classification number: C08F2/001 , B01J19/0033 , C08F2/00 , C08F20/56 , C08F2400/02 , C08F2500/05 , C08G85/00 , G01N11/04 , G01N21/65 , G05B13/04 , G06F17/11
Abstract: Devices and methods for actively controlling the production of multistage and multimodal polymers. The device may include a reaction vessel configured to contain a polymer solution and generate polymer reactions in at least two stages as well as one or more detectors configured to monitor at least one reaction characteristic of the polymer solution contained in the reaction vessel. The device may further include a controller coupled with the reaction vessel and the one or more detectors, the controller configured to actively control the development of a predetermined reaction characteristic by modifying at least one process control variable based on the at least one reaction characteristic monitored by the detector.
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8.发明申请公开(公告)号：US20180011024A1
公开(公告)日：2018-01-11
申请号：US15544176
申请日：2016-01-19
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
Inventor： Wayne Frederick Reed , Michael Felix Drenski
CPC classification number: E21B41/00 , B01J8/001 , B01J8/006 , B01J8/222 , B01J8/228 , B01J19/0006 , B01J19/18 , B01J19/1881 , B01J2208/00061 , B01J2208/00212 , B01J2208/00362 , B01J2208/00539 , B01J2208/00548 , B01J2208/00575 , B01J2208/00628 , B01J2208/00637 , B01J2208/00725 , B01J2208/00973 , B01J2219/0004 , B01J2219/00063 , B01J2219/00069 , B01J2219/00072 , B01J2219/00094 , B01J2219/00123 , B01J2219/00164 , B01J2219/00168 , B01J2219/00186 , B01J2219/002 , B01J2219/00216 , B01J2219/00218 , B01J2219/00225 , B01J2219/00231 , B01J2219/00236 , B01J2219/00238 , B01J2219/0024 , B01J2219/00243 , B01J2219/00272 , G01N11/08 , G01N21/19 , G01N21/21 , G01N21/23 , G01N21/272 , G01N21/33 , G01N21/35 , G01N21/47 , G01N21/64 , G01N21/65 , G01N21/75 , G01N21/84 , G01N2021/8416 , G01N2201/12
Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.
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公开(公告)号：US20150056710A1
公开(公告)日：2015-02-26
申请号：US14464658
申请日：2014-08-20
Inventor： Wayne Frederick Reed , Michael Felix Drenski , Alex Wayne Reed
CPC classification number: G01N15/0211 , G01N21/51 , G01N21/53 , G01N33/6803 , G01N2021/4711 , G01N2021/4719 , G01N2021/4726 , G01N2021/4792 , G01N2201/0612 , G01N2201/08 , G01N2201/1224
Abstract: Simultaneous Multiple Sample Light Scattering systems and methods can be used to for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces. among others, that create a polymer stress response used to characterize the polymer solution and stability.
Abstract translation: 同时多重样品光散射系统和方法可用于聚合物稳定性测试和将应激物施加到聚合物或胶体溶液，包括热应力，超声波，冻融循环，剪切应力和暴露于不同物质和表面。 其中，产生用于表征聚合物溶液和稳定性的聚合物应力响应。
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10.发明申请公开(公告)号：US20190154588A1
公开(公告)日：2019-05-23
申请号：US16254532
申请日：2019-01-22
Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC. , THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
Inventor： Wayne Frederick Reed , Michael Felix Drenski
Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.
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