BENZOTHIAZOLE COMPOUND AND MEDICINE CONTAINING SAME

    公开(公告)号:US20170197956A1

    公开(公告)日:2017-07-13

    申请号:US15326320

    申请日:2015-07-15

    Abstract: It is intended to provide: a compound useful as an amyloid oxidation catalyst which is applicable in vivo and is applicable not only to Aβ peptides but to other amyloids; and a prophylactic or therapeutic drug for an amyloid-related disease, comprising the same. The present invention provides a benzothiazole compound represented by the following formula (1) wherein X represents a halogen atom; R1 represents an optionally substituted hydrocarbon group; R2 represents a hydrogen atom or an optionally substituted hydrocarbon group; R3 and R4 are the same or different and each represent a hydrogen atom, an optionally substituted hydrocarbon group, an alkoxy group, a halogen atom, an amino group, a nitro group, or a cyano group; R2 and R4 optionally together form an alkylene group; and R5 represents an anion.

    Cobalt-base alloy with high heat resistance and high strength and process for producing the same
    100.
    发明授权
    Cobalt-base alloy with high heat resistance and high strength and process for producing the same 有权
    具有高耐热性和高强度的钴基合金及其制造方法

    公开(公告)号:US09453274B2

    公开(公告)日:2016-09-27

    申请号:US14017920

    申请日:2013-09-04

    CPC classification number: C22F1/10 C22C19/07

    Abstract: A process for producing a Co-base alloy which has a basic composition including, in terms of mass proportion, 0.1%-10% Al, 3.0-45% W, and Co as the remainder and has an intermetallic compound of the L12 type [Co3 (Al,W)] dispersed and precipitated therein. Part of the Co may be replaced with Ni, Ir, Fe, Cr, Re, or Ru, while part of the Al and W may be replaced with Ni, Ti, Nb, Zr, V, Ta or Hf. The intermetallic compound [Co3 (Al, W)] has a high melting point, and this compound and the matrix are mismatched little with respect to lattice constant. Thus, the cobalt-base alloy can have high-temperature strength equal to that of nickel-base alloys and excellent structure stability.

    Abstract translation: 一种钴基合金的制造方法,其具有以质量比计含有0.1%-10%Al,3.0-45%W和Co作为剩余部分的碱性组成,并具有L12型金属间化合物[ Co3(Al,W)]。 Co的一部分可以用Ni,Ir,Fe,Cr,Re或Ru代替,而Al和W的一部分可以被Ni,Ti,Nb,Zr,V,Ta或Hf代替。 金属间化合物[Co 3(Al,W)]具有高熔点,并且该化合物和基体相对于晶格常数几乎不匹配。 因此,钴基合金可以具有与镍基合金相当的高温强度和优异的结构稳定性。

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