公开(公告)号：US12044648B2

公开(公告)日：2024-07-23

申请号：US17132360

申请日：2020-12-23

Applicant: Abbott Diabetes Care Inc.

Inventor： John V. LaTour ,  Jonathan D. McCanless ,  Stephen Oja ,  Tianmei Ouyang ,  Kevin Paul Wallis ,  Benjamin J. Feldman ,  Udo Hoss ,  Suyue Qian

IPC: G01N27/327

CPC classification number: G01N27/3272 ,  G01N27/3277

Abstract: Analyte sensors responsive at low working electrode potentials may comprise an active area upon a surface of a working electrode, wherein the active area comprises a polymer, a redox mediator covalently bonded to the polymer, and at least one analyte-responsive enzyme covalently bonded to the polymer. A specific redox mediator responsive at low potential may have a structure of




wherein G is a linking group covalently bonding the redox mediator to the polymer. A mass transport limiting membrane permeable to the analyte may overcoat the active area. In some sensor configurations, the mass transport limiting membrane may comprise a membrane polymer crosslinked with a branched crosslinker comprising three or more crosslinkable groups, such as polyethylene glycol tetraglycidyl ether.

公开(公告)号：US20240027390A1

公开(公告)日：2024-01-25

申请号：US18223263

申请日：2023-07-18

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Udo Hoss ,  Max Garbett ,  Andrew James Bull ,  Stephen Oja ,  Benjamin J. Feldman ,  Lam N. Tran ,  Jean-Pierre Babka ,  Mark Stephen Yahnke ,  Tahir S. Khan ,  Adrian Petyt ,  Mark Alan Schulz ,  Andrew McGibbon ,  Owen Daniel Reynolds

IPC: G01N27/327 ,  G01N33/66

CPC classification number: G01N27/3273 ,  G01N27/3272 ,  G01N33/66

Abstract: Analyte sensor comprises a substrate having an upper surface including a first portion and a second exposed portion, an electrode layer disposed on the first portion and having an elongate body comprising a proximal end and a distal end, the electrode layer including an active working electrode area having a surface area of between 0.15 mm2 to 0.25 mm2, at least one sensing spot with at least one analyte responsive enzyme disposed on the active working electrode area. Additional analyte sensors are disclosed.

公开(公告)号：US20230389831A1

公开(公告)日：2023-12-07

申请号：US18454445

申请日：2023-08-23

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Udo Hoss ,  John Charles Mazza ,  Phu Le

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/14865 ,  A61B5/6833 ,  A61B5/7221 ,  A61B2562/227 ,  A61B5/002 ,  A61B2560/0443

Abstract: Low profile continuous analyte measurement systems and systems and methods for implantation within the skin of a patient are provided.

公开(公告)号：US11806141B2

公开(公告)日：2023-11-07

申请号：US17942684

申请日：2022-09-12

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Mohammad E. Moein ,  Louis G. Pace ,  Udo Hoss ,  Phu X. Le ,  Samuel Mason Curry

IPC: H05K5/00 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473 ,  H05K3/32 ,  H01L23/00 ,  H05K3/36

CPC classification number: A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4839 ,  A61B5/6848 ,  H05K3/325 ,  A61B2562/164 ,  A61B2562/227 ,  H01L24/72 ,  H01L2924/07811 ,  H01L2924/12042 ,  H05K3/365 ,  H05K2201/053 ,  H05K2201/10151 ,  H05K2201/10401 ,  H05K2201/10409 ,  Y10T29/4913 ,  H01L2924/07811 ,  H01L2924/00 ,  H01L2924/12042 ,  H01L2924/00

Abstract: Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.

公开(公告)号：US20230320626A1

公开(公告)日：2023-10-12

申请号：US18184910

申请日：2023-03-16

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Louis Pace ,  Jean-Pierre Cole ,  Udo Hoss ,  Steven Mitchell ,  Matthew Simmons

IPC: A61B5/145 ,  G16H40/67

CPC classification number: A61B5/145 ,  G16H40/67 ,  A61B2560/0406 ,  A61B2560/0462 ,  A61B2562/164 ,  A61B2562/242

Abstract: An analyte measurement device including an analyte sensor configured to measure an analyte level, the analyte sensor including a tail portion for subcutaneous placement, the tail portion having an analyte-responsive enzyme disposed thereon; an applicator for delivery of the analyte sensor, the applicator having a housing defining a hermetically-sealed chamber, the tail portion disposed within the chamber prior to subcutaneous placement; and a scavenger material disposed within the chamber, the scavenger material comprising at least one of activated carbon, molecular sieve, and silica gel and configured to adsorb at least one substance within the chamber. A method of packaging an analyte sensor is also disclosed.

公开(公告)号：US20230268071A1

公开(公告)日：2023-08-24

申请号：US18176293

申请日：2023-02-28

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Daniel Milfred Bernstein ,  Martin J. Fennell ,  Mark Kent Sloan ,  Michael Love ,  Lei He ,  Christopher Allen Thomas ,  Udo Hoss ,  Benjamin Jay Feldman ,  Kenneth J. Doniger ,  Gary Ashley Stafford ,  Gary Alan Hayter ,  Phillip Yee ,  Namvar Kiaie ,  Jean-Pierre Cole ,  Marc Barry Taub ,  Louis George Pace ,  Jeffery Mario Sicurello

IPC: G16H40/67 ,  G01N33/487 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01 ,  G16H40/63

CPC classification number: G16H40/67 ,  G01N33/48792 ,  A61B5/0017 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/72 ,  G16H40/63 ,  Y02A90/10 ,  A61B2560/0238

Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

公开(公告)号：US20230238131A1

公开(公告)日：2023-07-27

申请号：US18130381

申请日：2023-04-03

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Daniel Milfred Bernstein ,  Martin J. Fennell ,  Mark Kent Sloan ,  Michael Love ,  Lei He ,  Christopher Allen Thomas ,  Udo Hoss ,  Benjamin Jay Feldman ,  Kenneth J. Doniger ,  Gary Ashley Stafford ,  Gary Alan Hayter ,  Phillip Yee ,  Namvar Kiaie ,  Jean-Pierre Cole ,  Marc Barry Taub ,  Louis George Pace ,  Jeffery Mario Sicurello

IPC: G16H40/67 ,  G01N33/487 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01 ,  G16H40/63

CPC classification number: G16H40/67 ,  G01N33/48792 ,  A61B5/0017 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/72 ,  G16H40/63 ,  Y02A90/10 ,  A61B2560/0238

Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

公开(公告)号：US20230028587A1

公开(公告)日：2023-01-26

申请号：US17950538

申请日：2022-09-22

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Steven Scott ,  Christopher J. Bennell ,  Claire Bhogal ,  Katie A. Cranfield ,  Marc B. Taub ,  Bree M. Winter ,  Owen D. Reynolds ,  Jean-Pierre Babka ,  Dharmendra S. Patel ,  Christopher A. Thomas ,  Udo Hoss ,  Mark S. Yahnke ,  Tahir S. Khan

IPC: A61B5/1495 ,  A61B5/145

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

公开(公告)号：USD957642S1

公开(公告)日：2022-07-12

申请号：US29776978

申请日：2021-04-01

Applicant: ABBOTT DIABETES CARE INC.

Designer： Christopher Allen Thomas ,  Udo Hoss ,  Martin J. Fennell ,  Lei He ,  Michael Love ,  Phillip Yee

公开(公告)号：US11382542B2

公开(公告)日：2022-07-12

申请号：US17513588

申请日：2021-10-28

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Mohammad E. Moein ,  Louis G. Pace ,  Udo Hoss ,  Phu X. Le ,  Samuel Mason Curry

IPC: H05K5/00 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473 ,  H05K3/32 ,  H01L23/00 ,  H05K3/36

Abstract: Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.