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    Wavelength-Tunable Detector For Label-Independent Optical Reader
    92.
    发明申请
    Wavelength-Tunable Detector For Label-Independent Optical Reader 有权
    用于标签无关光学读取器的波长可调检测器

    公开(公告)号：US20140071450A1

    公开(公告)日：2014-03-13

    申请号：US13613974

    申请日：2012-09-13

    Applicant: David Andrew Pastel ,  Cameron John Tovey

    Inventor： David Andrew Pastel ,  Cameron John Tovey

    IPC: G01J3/51

    CPC classification number: G01N21/774

    Abstract: A wavelength-tunable detector for use in a label-independent optical reader for reading at least one resonant waveguide grating (RWG) biosensor is disclosed. The wavelength-tunable detector includes a tunable wavelength filter. Broadband light is made incident upon the RWG biosensor to produce resonantly reflected light, which is then passed through the tunable wavelength filter whose central wavelength is adjusted, such as by varying the filter angle of the tunable wavelength filter. This generates filtered resonantly reflected light, which is detected by a photodetector that generates an electrical signal in response thereto. The electrical signal is representative of the detected spectrum, which includes the center resonant wavelength of the RWG biosensor. A controller can be used to determine the center resonant wavelength from the electrical signal.

    Abstract translation: 公开了一种用于读取至少一个谐振波导光栅（RWG）生物传感器的标签无关光学读取器中的波长可调检测器。 波长可调检测器包括可调波长滤波器。 宽带光入射到RWG生物传感器上以产生共振的反射光，然后通过调节中心波长的可调谐波长滤波器，例如通过改变可调波长滤波器的滤光角度。 这产生滤波的共振反射光，该光被由响应于此产生电信号的光电检测器检测。 电信号表示检测到的光谱，其包括RWG生物传感器的中心谐振波长。 可以使用控制器来确定来自电信号的中心谐振波长。

    BEAM SPLITTER MODULE
    95.
    发明申请
    BEAM SPLITTER MODULE 失效
    光束分离器模块

    公开(公告)号：US20120193520A1

    公开(公告)日：2012-08-02

    申请号：US13363030

    申请日：2012-01-31

    Applicant: Joerg Bewersdorf ,  Brian Thomas Bennett

    Inventor： Joerg Bewersdorf ,  Brian Thomas Bennett

    IPC: G01J1/04 ,  G01J3/51

    CPC classification number: G02B27/145 ,  G02B19/0028 ,  G02B19/0057 ,  G02B19/0066 ,  G02B27/1006 ,  G02B27/14 ,  G02B27/141 ,  G02B27/144

    Abstract: A primary beam splitter (310) of an optical apparatus (300) can be used to split an incident light beam (305) into a primary plurality of light beams and to direct a first beam of the primary plurality of light beams in a first direction and a second beam of the primary plurality of light beams in a second direction orthogonal to the first direction. Secondary beam splitters (315a,b) positioned in beam paths of the first and second beams can be used to split the first and second beams of the primary plurality of light beams into a secondary plurality of light beams (320a,b) and to split the second beam of the primary plurality of light beams into a tertiary plurality of light beams (325a,b). A primary plurality of beam reflectors (335a,b/340a,b/345a,b) can be positioned and used to redirect the secondary and tertiary plurality of light beams toward a common detector (355).

    Abstract translation: 可以使用光学设备（300）的主分束器（310）将入射光束（305）分裂成主要的多个光束并且将第一个多个光束的第一光束沿第一方向 以及在与第一方向正交的第二方向上的主多个光束的第二光束。 定位在第一和第二光束的光束路径中的次级光束分离器（315a，b）可用于将主要多个光束的第一和第二光束分成次级多个光束（320a，b）并分裂 所述主多个光束的第二光束成为第三多个光束（325a，b）。 可以将主要的多个光束反射器（335a，b / 340a，b / 345a，b）定位并用于将次级和第三级光束朝着公共检测器（355）重定向。

    Observation device and wavelength limiting filter
    96.
    发明授权
    Observation device and wavelength limiting filter 有权
    观察装置和波长限制滤波器

    公开(公告)号：US08159675B2

    公开(公告)日：2012-04-17

    申请号：US12461013

    申请日：2009-07-29

    Applicant: Yasujiro Kiyota

    Inventor： Yasujiro Kiyota

    IPC: G01J3/51 ,  G02B21/00

    CPC classification number: G02B21/14 ,  G01N21/25 ,  Y10S435/808

    Abstract: An observation device observing a sample cultured in a culture vessel includes an illuminating unit including an illumination optical system and illuminating the sample, an image-capturing unit including an imaging sensor and generating an image by capturing an image of the sample illuminated by the illuminating unit, and a wavelength limiting filter being placed on an optical axis of the illumination optical system and between the illuminating unit and the image-capturing unit, and limiting a part of wavelengths of an illumination light from the illumination optical system in accordance with optical absorption properties of an additive contained in a culture medium used for culturing the sample. Accordingly, it is possible to suppress a change of the image resulting from the additive and to enable to generate an appropriate image in an automatic observation.

    Abstract translation: 观察在培养容器中培养的样本的观察装置包括：照明单元，包括照明光学系统和照射样本;图像捕获单元，包括成像传感器，并且通过拍摄由照明单元照射的样本的图像来产生图像; 以及波长限制滤光器，其被放置在照明光学系统的光轴上，并且在照明单元和图像捕获单元之间，并且根据光吸收特性限制来自照明光学系统的照明光的一部分波长 包含在用于培养样品的培养基中的添加剂。 因此，可以抑制由添加剂产生的图像的变化，并且能够在自动观察中产生适当的图像。

    Optical Sensing System Including Electronically Switched Optical Magnification
    97.
    发明申请
    Optical Sensing System Including Electronically Switched Optical Magnification 有权
    包括电子开关光学放大的光学感应系统

    公开(公告)号：US20120050741A1

    公开(公告)日：2012-03-01

    申请号：US13216507

    申请日：2011-08-24

    Applicant: Alexander N. Artsyukhovich

    Inventor： Alexander N. Artsyukhovich

    IPC: G01J3/51

    CPC classification number: G01D5/34 ,  G01L9/0077 ,  G02B15/00 ,  G02B21/0004

    Abstract: Disclosed is an exemplary optical sensing system including at least one light source for emitting light in a first wavelength range and light in a second wavelength. An image sensor is provided for detecting light emitted from the at least one light source. The optical sensing system also includes a first optical filter disposed in a first optical path extending between the light source and the image sensor, the first optical filter configured to pass light emitted in the first wavelength range, and to substantially block light emitted in the second wavelength range. A second optical filter is disposed in a second optical path extending between the light source and the image sensor, the second optical filter configured to pass light emitted from the at least one light source in the second wavelength range, and to substantially block light emitted in the first wavelength range.

    Abstract translation: 公开了一种示例性光学感测系统，其包括用于发射第一波长范围的光和第二波长的光的至少一个光源。 提供一种用于检测从至少一个光源发出的光的图像传感器。 光学传感系统还包括设置在光源和图像传感器之间延伸的第一光路中的第一光学滤光器，第一滤光器被配置为使在第一波长范围内发射的光通过，并基本上阻挡在第二光源中发射的光 波长范围。 第二滤光器设置在在光源和图像传感器之间延伸的第二光路中，第二滤光器被配置为将来自至少一个光源的光在第二波长范围内通过，并基本上阻挡在 第一波长范围。

    Extended depth of field imaging for high speed object analysis
    98.
    发明授权
    Extended depth of field imaging for high speed object analysis 有权
    用于高速物体分析的扩展景深成像

    公开(公告)号：US08009189B2

    公开(公告)日：2011-08-30

    申请号：US12132394

    申请日：2008-06-03

    Applicant: William Ortyn ,  David Basiji ,  Keith Frost ,  Luchuan Liang ,  Richard Bauer ,  Brian Hall ,  David Perry

    Inventor： William Ortyn ,  David Basiji ,  Keith Frost ,  Luchuan Liang ,  Richard Bauer ,  Brian Hall ,  David Perry

    IPC: G01J3/28 ,  G01J3/51

    CPC classification number: G02B27/0075 ,  G01N15/147 ,  G01N15/1475 ,  G01N21/6458 ,  G01N2015/1452 ,  G02B21/365 ,  G02B27/0012

    Abstract: A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element.

    Abstract translation: 改进了高速，高分辨率流动成像系统，以实现扩展的景深成像。 光学失真元件被引入到流动成像系统中。 来自诸如单元的物体的光被失真元件扭曲，使得成像系统的点扩散函数（PSF）在扩展的景深范围内是不变的。 失真光被光谱分散，并且分散的光被用于同时产生多个图像。 检测图像，并且使用图像处理来通过补偿失真来增强检测到的图像，以实现对象的扩展景深图像。 后图像处理优选地涉及去卷积，并且需要由光学失真元件修改的成像系统的PSF的知识。

    Color sensors using polarimetric techniques
    99.
    发明授权
    Color sensors using polarimetric techniques 有权
    彩色传感器采用偏光技术

    公开(公告)号：US07812951B2

    公开(公告)日：2010-10-12

    申请号：US11863001

    申请日：2007-09-27

    Applicant: Francis Lawrence Leard ,  Nelson D. Sheppard ,  Patrick J. Delaney, III ,  Shaun Paul Hentchel

    Inventor： Francis Lawrence Leard ,  Nelson D. Sheppard ,  Patrick J. Delaney, III ,  Shaun Paul Hentchel

    IPC: G01J3/51

    CPC classification number: G01J3/02 ,  G01J3/0224 ,  G01J3/0264 ,  G01J3/447 ,  G01J3/50 ,  G01J3/501 ,  G01J3/51 ,  G01N21/21 ,  G01N21/25

    Abstract: Embodiments include an apparatus including a color sensor including a transmitter portion and a receiver portion, the transmitter portion including a light source operable to generate and transmit a light having a particular range of wavelengths, the receiver portion including a first detector operable to receive a first portion of the light emitted from the transmitter portion and to measure a luminance of the received first portion of the emitted light, and a second detector including a polarization filter, the second detector operable to receive a second portion of the light emitted from the transmitter after the second portion has passed through the polarization filter, and operable to measure a pure color of the received second portion of transmitted light.

    Abstract translation: 实施例包括一种包括具有发射器部分和接收器部分的颜色传感器的装置，所述发射器部分包括可操作以产生和发射具有特定波长范围的光的光源，所述接收器部分包括可操作以接收第一 从所述发射器部分发射的光的一部分并且测量所接收的所述发射光的第一部分的亮度;以及第二检测器，其包括偏振滤光器，所述第二检测器可操作以在所述发射器之后接收从所述发射器发射的光的第二部分， 第二部分已经通过偏振滤光器，并且可操作以测量所接收的第二部分透射光的纯色。

    Methods for improving the performance of a detector
    100.
    发明授权
    Methods for improving the performance of a detector 有权
    提高检测器性能的方法

    公开(公告)号：US07764378B2

    公开(公告)日：2010-07-27

    申请号：US12138151

    申请日：2008-06-12

    Applicant: Mark F. Oldham

    Inventor： Mark F. Oldham

    IPC: G01J3/51 ,  C12M1/34

    CPC classification number: H04N5/335

    Abstract: A system and method for allowing adjustments of various parameters associated with the operation of charge-coupled devices adapted for use in biological analysis devices. Gate voltage signal applied to the CCDs can be adjusted to advantageously affect the manner in which charge is transferred from pixels. The manner in which transferred charges from the pixels are processed in a readout process can also be adjusted to advantageously change the speed of the CCD based detector. Various methods of performing such adjustments are disclosed.

    Abstract translation: 一种用于允许调整与适于在生物分析装置中使用的电荷耦合装置的操作相关联的各种参数的系统和方法。 可以调整施加到CCD的栅极电压信号以有利地影响从像素传送电荷的方式。 在读出处理中处理来自像素的传送电荷的方式也可以被调整以有利地改变基于CCD的检测器的速度。 公开了进行这种调整的各种方法。

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