公开(公告)号：US20160299058A1

公开(公告)日：2016-10-13

申请号：US15093745

申请日：2016-04-08

Applicant: Taiwan Biophotonic Corporation

Inventor： YU-TANG LI ,  CHANG-SHENG CHU ,  PEI-CHENG HO ,  KUAN-JUI HO ,  SHUANG-CHAO CHUNG ,  CHIH-HSUN FAN ,  JYH-CHERN CHEN

IPC: G01N21/21

CPC classification number: G01N21/21 ,  A61B3/10 ,  A61B3/152 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  G01B11/272 ,  G01N33/483 ,  G01N2201/0633 ,  G01N2201/0683 ,  G01N2201/126

Abstract: The present disclosure generally relates to an optical measurement module, an optical measurement device, and a method for optical measurement. The optical measurement module provides optical architecture to measure the optical properties of an analyte. The optical measurement device comprising the optical measurement module is configured to measure the optical properties of an analyte. The method for the optical measurement provides steps for optical measurement.

Abstract translation: 本公开一般涉及光学测量模块，光学测量装置和用于光学测量的方法。 光学测量模块提供光学架构来测量分析物的光学性质。 包括光学测量模块的光学测量装置被配置为测量分析物的光学性质。 光学测量的方法提供光学测量的步骤。

公开(公告)号：US09465015B2

公开(公告)日：2016-10-11

申请号：US14538181

申请日：2014-11-11

Applicant: VUVA Analytics, Inc.

Inventor： Dale A. Harrison ,  Anthony T. Hayes ,  Phillip Walsh

IPC: G01N21/00 ,  G01N30/74 ,  G01N21/33 ,  G01J3/02 ,  G01N30/02 ,  G01N33/00 ,  G01N21/15 ,  G01N21/05 ,  G01N21/03

CPC classification number: G01N30/78 ,  G01J3/02 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/15 ,  G01N21/33 ,  G01N30/02 ,  G01N30/74 ,  G01N33/0004 ,  G01N33/0027 ,  G01N2021/0325 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/335 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2201/024 ,  G01N2201/0633 ,  G01N2201/12 ,  G01N30/7266

Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.

公开(公告)号：US20160282332A1

公开(公告)日：2016-09-29

申请号：US15175013

申请日：2016-06-06

Applicant: Concordia Laboratories Inc.

Inventor： Michael Scot ROBERTS

IPC: G01N33/50 ,  G01N21/25 ,  F21V9/04 ,  F21V5/04 ,  F21V13/02 ,  F21V13/14 ,  F21V7/00 ,  C12N13/00 ,  F21V5/00

CPC classification number: G01N33/5011 ,  A61K41/00 ,  C12N13/00 ,  C12Q1/22 ,  F21V5/00 ,  F21V5/04 ,  F21V7/00 ,  F21V9/04 ,  F21V13/02 ,  F21V13/14 ,  G01N21/255 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0686

Abstract: Presently disclosed is a lighting system and methods of using the lighting system for in vitro potency assay for photofrin. The lighting system includes a lamp housing, a first lens, an infrared absorbing filter, an optical filter, and a second lens. The lamp housing includes a lamp and a light-port. In operation, broad spectrum light from the lamp exits the lamp housing by passing through the light-port. The first lens then collimates the broad spectrum light that exits the lamp housing through the light-port. The infrared absorbing filter then passes a first portion of the collimated broad spectrum light to the optical filter and absorbs infrared light of the broad spectrum light. The optical filter then passes a second portion of the collimated broad spectrum light to the second lens. The second lens then disperses the second portion of the collimated light to provide uniform irradiation of a cell culture plate. A method of using the lighting system for studying a photosensitizer is also disclosed.

Abstract translation: 目前公开的是一种照明系统和使用该照明系统进行光镊的体外效力测定的方法。 照明系统包括灯壳体，第一透镜，红外吸收滤光器，滤光器和第二透镜。 灯壳包括灯和光端口。 在操作中，来自灯的广谱光通过灯光而离开灯壳。 然后，第一透镜使通过光端口离开灯壳体的广谱光束准直。 然后，红外线吸收滤光器将准直的广谱光的第一部分通过光学滤光器并吸收广谱光的红外光。 然后，滤光器将准直的广谱光的第二部分通过第二透镜。 然后第二透镜分散准直光的第二部分以提供细胞培养板的均匀照射。 还公开了使用照明系统研究光敏剂的方法。

公开(公告)号：US20160266046A1

公开(公告)日：2016-09-15

申请号：US15029472

申请日：2014-10-13

Applicant: PHILIPS LIGHTING HOLDING B.V.

Inventor： SHUGUANG KUAI ,  MARK CHRISTOPH JAEGER ,  WEIXI ZHOU

IPC: G01N21/88 ,  H04N5/225

CPC classification number: G01N21/8806 ,  G01N21/8803 ,  G01N2021/8809 ,  G01N2201/0633 ,  G01N2201/12 ,  H04N5/225

Abstract: A defect inspection system is provided for inspection of defects in the surface of a sample. An array of light sources is used, with different light sources providing light to the sample from different directions. A main direction of illumination is defined with highest intensity, and this direction evolves over time. By providing varying directional illumination instead of blanket illumination, it becomes easier to detect defects.

Abstract translation: 提供缺陷检查系统用于检查样品表面的缺陷。 使用一组光源，不同的光源从不同的方向向样品提供光。 照明的主要方向被定义为具有最高强度，并且该方向随着时间而演变。 通过提供不同的定向照明而不是毯式照明，变得更容易检测缺陷。

公开(公告)号：US20160238535A1

公开(公告)日：2016-08-18

申请号：US15140707

申请日：2016-04-28

Applicant: SciAps, Inc.

Inventor： David R. Day ,  Konstantin Derman ,  John Francis Egan ,  Paul Edward Soucy

IPC: G01N21/71 ,  G01J3/443 ,  G01J3/10 ,  G01J3/02

CPC classification number: G01J3/0272 ,  G01J3/0208 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2823 ,  G01J3/443 ,  G01J2003/2879 ,  G01N21/718 ,  G01N2201/0221 ,  G01N2201/06113 ,  G01N2201/0633

Abstract: A handheld LIBS spectrometer includes an optics stage movably mounted to a housing and including a laser focusing lens and a detection lens. One or more motors advance and retract the optics stage, move the optics stage left and right, and/or move the optics stage up and down. A laser source in the housing is oriented to direct a laser beam to the laser focusing lens. A spectrometer subsystem in the housing is configured to receive electromagnetic radiation from the detection lens and to provide an output. A controller subsystem is responsive to the output of the spectrometer subsystem and is configured to control the laser source and motors. In this way, auto-calibration, auto-clean, and auto-focus, and/or moving spot functionality is possible.

Abstract translation: 手持式LIBS光谱仪包括可移动地安装到壳体并包括激光聚焦透镜和检测透镜的光学台。 一个或多个电机推进和缩回光学平台，左右移动光学台，和/或上下移动光学平台。 壳体中的激光源被定向成将激光束引导到激光聚焦透镜。 外壳中的光谱仪子系统被配置为从检测透镜接收电磁辐射并提供输出。 控制器子系统响应于光谱仪子系统的输出，并被配置为控制激光源和电动机。 这样就可以进行自动校准，自动清理和自动对焦，和/或移动点功能。

公开(公告)号：US09371555B2

公开(公告)日：2016-06-21

申请号：US13689490

申请日：2012-11-29

Applicant: Pinnacle Biologics, Inc.

Inventor： Michael S. Roberts

IPC: F21V13/02 ,  C12Q1/22 ,  G01N33/50 ,  G01N21/25 ,  A61K41/00

CPC classification number: G01N33/5011 ,  A61K41/00 ,  C12N13/00 ,  C12Q1/22 ,  F21V5/00 ,  F21V5/04 ,  F21V7/00 ,  F21V9/04 ,  F21V13/02 ,  F21V13/14 ,  G01N21/255 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0686

Abstract: Presently disclosed is a lighting system and methods of using the lighting system for in vitro potency assay for photofrin. The lighting system includes a lamp housing, a first lens, an infrared absorbing filter, an optical filter, and a second lens. The lamp housing includes a lamp and a light-port. In operation, broad spectrum light from the lamp exits the lamp housing by passing through the light-port. The first lens then collimates the broad spectrum light that exits the lamp housing through the light-port. The infrared absorbing filter then passes a first portion of the collimated broad spectrum light to the optical filter and absorbs infrared light of the broad spectrum light. The optical filter then passes a second portion of the collimated broad spectrum light to the second lens. The second lens then disperses the second portion of the collimated light to provide uniform irradiation of a cell culture plate. A method of using the lighting system for studying a photosensitizer is also disclosed.

Abstract translation: 目前公开的是一种照明系统和使用该照明系统进行光镊的体外效力测定的方法。 照明系统包括灯壳体，第一透镜，红外吸收滤光器，滤光器和第二透镜。 灯壳包括灯和光端口。 在操作中，来自灯的广谱光通过灯光而离开灯壳。 然后，第一透镜使通过光端口离开灯壳体的广谱光束准直。 然后，红外线吸收滤光器将准直的广谱光的第一部分通过光学滤光器并吸收广谱光的红外光。 然后，滤光器将准直的广谱光的第二部分通过第二透镜。 然后第二透镜分散准直光的第二部分以提供细胞培养板的均匀照射。 还公开了使用照明系统研究光敏剂的方法。

公开(公告)号：US20160109365A1

公开(公告)日：2016-04-21

申请号：US14890428

申请日：2013-05-13

Applicant: HACH LANGE GMBH

Inventor： BARBARA HAASE ,  MANFRED BATTEFELD ,  ANDREAS MITREITER ,  MICHAEL KUSSMANN ,  BAS DE HEIJ ,  CLEMENS HANSCHKE ,  WAYNE PERDUE

IPC: G01N21/51

CPC classification number: G01N21/51 ,  G01N21/53 ,  G01N2021/513 ,  G01N2201/0633 ,  G01N2201/0636

Abstract: A turbidimeter for measuring a turbidity of a liquid sample in a sample cuvette includes a cuvette receiving device configured to position the sample cuvette in a defined cuvette position, a light source configured to generate a parallel light beam in the sample cuvette, an annular 45° collecting mirror configured to surround the sample cuvette, a scattering body arranged concentric to the annular 45° collecting minor, a scattering light detector arranged to receive light scattered by the scattering body, and an annular 45° concentration minor arranged coaxially to the annular 45° collecting minor and optically opposite to the annular 45° collecting mirror. The annular 45° collecting minor is arranged concentric to the light beam. The annular 45° concentration minor is configured to surround the scattering body.

Abstract translation: 用于测量样品比色皿中的液体样品的浊度的浊度计包括配置成将样品比色皿定位在规定的比色杯位置的比色皿接收装置，被配置为在样品比色皿中产生平行光束的光源，环形45° 收集反射镜，被配置为围绕样品比色皿，散射体，其与环形45°收集小体同心地布置;散射光检测器，被布置成接收由散射体散射的光;以及环形45°浓度， 收集较小的并且与环形45°收集镜的光学相对。 环形45°收集小号与光束同心设置。 环形45°浓度次要构造成围绕散射体。

公开(公告)号：US20150316476A1

公开(公告)日：2015-11-05

申请号：US14649096

申请日：2013-11-29

Applicant: HORIBA JOBIN YVON SAS

Inventor： Olivier ACHER ,  Simon RICHARD ,  Christian BRACH ,  Viviane MILLET ,  Sebastien CORDE ,  Daphne HERAN

IPC: G01N21/64 ,  G01J3/18 ,  G01J3/447 ,  G01J3/02

CPC classification number: G01N21/645 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/18 ,  G01J3/447 ,  G01N2201/063 ,  G01N2201/0633 ,  G02B5/1866 ,  G02B27/283

Abstract: A spectrometer (100) for analyzing the spectrum of an upstream light beam (1), includes an entrance slit (101) and collimating elements (110) suitable for generating, from the upstream light beam, a collimated light beam (10), characterized in that it also includes: a polarization-dependent diffraction grating (120) suitable for diffracting, at each wavelength (11, 12) of the spectrum of the upstream light beam, the collimated light beam into a first diffracted light beam (11, 12) and a second diffracted light beam (21, 22); optical recombining elements (130) including a planar optical reflecting surface (130) perpendicular to the grating and suitable for deviating at least the second diffracted light beam; and focussing elements (140) suitable for focussing, at each wavelength, the first diffracted light beam and the second diffracted light beam onto one and the same focussing area (141).

Abstract translation: 用于分析上游光束（1）的光谱的光谱仪（100）包括入射狭缝（101）和适于从上游光束产生准直光束（10）的准直元件（110），其特征在于 因为它还包括：适用于在上游光束的光谱的每个波长（11,12）衍射的偏振相关衍射光栅（120），准直光束成为第一衍射光束（11,12 ）和第二衍射光束（21,22）; 光学重组元件（130），包括垂直于光栅的平面光学反射表面（130），并且适于至少偏离第二衍射光束; 以及适于在每个波长处将第一衍射光束和第二衍射光束聚焦到同一聚焦区域（141）上的聚焦元件（140）。

公开(公告)号：US20150131100A1

公开(公告)日：2015-05-14

申请号：US14405938

申请日：2013-06-06

Applicant: Technical University of Denmark

Inventor： Kasper Reck ,  Christian Østergaard ,  Ole Hansen ,  Erik Vilain Thomsen

IPC: G01L1/24 ,  G02B6/10 ,  G01N21/55

CPC classification number: G01L1/246 ,  G01L11/02 ,  G01N21/55 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/084 ,  G02B6/10

Abstract: The present invention relates to an all-optical sensor utilizing effective index modulation of a waveguide and detection of a wavelength shift of reflected light and a force sensing system accommodating said optical sensor. One embodiment of the invention relates to a sensor system comprising at least one multimode light source, one or more optical sensors comprising a multimode sensor optical waveguide accommodating a distributed Bragg reflector, at least one transmitting optical waveguide for guiding light from said at least one light source to said one or more multimode sensor optical waveguides, a detector for measuring light reflected from said Bragg reflector in said one or more multimode sensor optical waveguides, and a data processor adapted for analyzing variations in the Bragg wavelength of at least one higher order mode of the reflected light.

Abstract translation: 本发明涉及利用波导的有效折射率调制和检测反射光的波长偏移的全光学传感器以及容纳所述光学传感器的力感测系统。 本发明的一个实施例涉及包括至少一个多模光源的传感器系统，一个或多个光学传感器，其包括容纳分布式布拉格反射器的多模传感器光波导，至少一个发射光波导，用于引导来自所述至少一个光的光 源到所述一个或多个多模传感器光波导，用于测量在所述一个或多个多模传感器光波导中从所述布拉格反射器反射的光的检测器，以及适于分析至少一个高阶模的布拉格波长的变化的数据处理器 的反射光。

公开(公告)号：US20150059440A1

公开(公告)日：2015-03-05

申请号：US14538181

申请日：2014-11-11

Applicant: VUV Analytics, Inc.

Inventor： Dale A. Harrison ,  Anthony T. Hayes ,  Phillip Walsh

IPC: G01N30/74 ,  G01N33/00

CPC classification number: G01N30/78 ,  G01J3/02 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/15 ,  G01N21/33 ,  G01N30/02 ,  G01N30/74 ,  G01N33/0004 ,  G01N33/0027 ,  G01N2021/0325 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/335 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2201/024 ,  G01N2201/0633 ,  G01N2201/12 ,  G01N30/7266

Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.

Abstract translation: 提供了一种有效的吸收光谱系统。 光谱系统可以被配置为测量固体，液体或气体样品。 可以使用真空紫外线波长。 一些所公开的技术可用于检测痕量浓度的气态物质的存在。 公开了一种优选的气体流通池。 所公开的技术中的一些可以与气相色谱系统一起使用，以便检测和鉴定从柱洗脱的物质。 所公开的技术中的一些可以与电喷雾界面和液相色谱系统结合使用，以便检测和鉴定由溶液产生的大分子的气相离子。 所公开的技术中的一些可以用于表征化学反应。 一些所公开的技术可以与超短路径长度的样品池结合使用以测量液体。