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公开(公告)号：US20150177133A1
公开(公告)日：2015-06-25
申请号：US14490242
申请日：2014-09-18
Applicant: Alison Hearn , David Feld , Jonathan Feld
Inventor： Wonshik Choi , Ramachandra Dasari , Christopher Fang-Yen , Michael Feld
CPC classification number: G01N21/45 , G01N21/51 , G01N21/6458 , G01N21/6486 , G01N2021/458 , G01N2201/061 , G01N2201/105 , G01N2201/12
Abstract: The present invention relates to systems and methods for quantitative three-dimensional mapping of refractive index in living or non-living cells, tissues, or organisms using a phase-shifting laser interferometric microscope with variable illumination angle. A preferred embodiment provides tomographic imaging of cells and multicellular organisms, and time-dependent changes in cell structure and the quantitative characterization of specimen-induced aberrations in high-resolution microscopy with multiple applications in tissue light scattering.
Abstract translation: 本发明涉及使用具有可变照明角度的移相激光干涉显微镜在生活或非活细胞，组织或生物体中定量三维映射折射率的系统和方法。 优选的实施方案提供细胞和多细胞生物的层析成像，以及在组织光散射中具有多种应用的高分辨率显微镜中细胞结构的时间依赖性变化和样品诱导的像差的定量表征。
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公开(公告)号：US20150089751A1
公开(公告)日：2015-04-02
申请号：US14501010
申请日：2014-09-29
Applicant: COLORIGHT LTD.
Inventor： Benzion Landa , Efraim Miklatzky , Sagi Abramovich , Yacov Mazuz , Anton Krassilnikov , Eliyahu Benny , Gilad Davara , Chen Ofek , Elena Ishkov , Lior Shahar , Daniel Mandelik , Uri Zadok
CPC classification number: A61Q5/10 , A61K8/0216 , A61K2800/4322 , B65D1/0223 , B65D83/04 , B65D2501/0081 , G01J3/02 , G01J3/18 , G01J3/42 , G01N21/21 , G01N21/27 , G01N21/4738 , G01N21/84 , G01N2201/062 , G01N2201/105
Abstract: Novel systems and methods for performing treatment (e.g., coloration) of keratinous fibers are disclosed. The methods and systems utilize one or more of a dispensing device which is configured to provide customized composition for treating keratinous fibers (e.g., a coloring composition), optionally formed from tablets; an optical reader, for obtaining sufficient characteristics of the keratinous fibers to make a realistic prediction of the outcome of a treatment (e.g., coloring treatment); a computational units for predicting an outcome of a treatment, optionally being interfaced with the dispensing device and for selecting a customized treatment; and tablet formulations which are useful in preparing customized composition for treating keratinous fibers. Further disclosed are rapidly disintegrating tablets for use in the preparation of compositions for treating keratinous fibers.
Abstract translation: 公开了用于进行角质纤维的处理（例如着色）的新型系统和方法。 所述方法和系统利用一种或多种分配装置，所述分配装置被配置为提供定制的组合物，用于治疗可选地由片剂形成的角质纤维（例如着色组合物） 光学读取器，用于获得角质纤维的足够特征以对治疗结果进行现实预测（例如着色处理）; 用于预测治疗结果的计算单元，可选地与分配装置接口并用于选择定制治疗; 以及可用于制备用于治疗角质纤维的定制组合物的片剂制剂。 进一步公开的是用于制备用于治疗角质纤维的组合物的快速崩解片剂。
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公开(公告)号：US20150069241A1
公开(公告)日：2015-03-12
申请号：US14542580
申请日：2014-11-15
Applicant: KLA-Tencor Corporation
Inventor： Steven R. Lange
CPC classification number: G01N21/9501 , G01N21/3563 , G01N21/359 , G01N21/55 , G01N21/9503 , G01N2201/0612 , G01N2201/105
Abstract: Multi-spectral defect inspection for 3D wafers is provided. One system configured to detect defects in one or more structures formed on a wafer includes an illumination subsystem configured to direct light in discrete spectral bands to the one or more structures formed on the wafer. At least some of the discrete spectral bands are in the near infrared (NIR) wavelength range. Each of the discrete spectral bands has a bandpass that is less than 100 nm. The system also includes a detection subsystem configured to generate output responsive to light in the discrete spectral bands reflected from the one or more structures. In addition, the system includes a computer subsystem configured to detect defects in the one or more structures on the wafer using the output.
Abstract translation: 提供了三维晶圆的多光谱缺陷检测。 被配置为检测在晶片上形成的一个或多个结构中的缺陷的一个系统包括被配置为将离散光谱带中的光引导到在晶片上形成的一个或多个结构的照明子系统。 至少一些离散的光谱带处于近红外（NIR）波长范围。 每个离散的光谱带具有小于100nm的带通。 该系统还包括检测子系统，该检测子系统被配置为响应于从一个或多个结构反映的离散频谱带中的光产生输出。 另外，该系统包括被配置为使用输出来检测晶片上的一个或多个结构中的缺陷的计算机子系统。
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公开(公告)号：US20150062582A1
公开(公告)日：2015-03-05
申请号：US14454052
申请日：2014-08-07
Applicant: RICOH COMPANY. LTD.
Inventor： Kazuhiko ADACHI , Yoshihiro OBA , Toshihiro ISHII , Fumikazu HOSHI , Sunao CHUBACHI , Yoshihiro MISAKA
CPC classification number: G01N21/21 , G01B11/06 , G01G9/00 , G01N21/4738 , G01N21/59 , G01N2201/06113 , G01N2201/062 , G01N2201/0691 , G01N2201/105 , G03G15/5029 , G03G2215/00616 , G03G2215/00738 , G03G2215/00742
Abstract: A sensor apparatus includes an irradiation system with a light source configured to emit linearly polarized light of a first polarization direction onto a sheet-like object, in a direction oblique to a direction orthogonal to a surface of the object, a first photodetector arranged on an optical path of light that is emitted from the irradiation system and then is reflected at the object by regular reflection, a first optical element, arranged on an optical path of light reflected by diffuse reflection from an incidence plane of the object, configured to transmit linearly polarized light of a second polarization direction that is orthogonal to the first polarization direction, a second photodetector configured to receive light that has passed through the first optical element, and a detection unit configured to detect at least one of basis weight and thickness of the object.
Abstract translation: 一种传感器装置，包括具有光源的照射系统，被配置为沿与物体的表面正交的方向倾斜的方向将第一偏振方向的线偏振光发射到片状物体上;第一光电检测器， 从照射系统发射的光的光路，然后通过规则反射在物体处反射;第一光学元件，布置在从物体的入射平面漫反射反射的光的光路上，被配置为线性地透射 与第一偏振方向正交的第二偏振方向的偏振光，被配置为接收通过第一光学元件的光的第二光电检测器，以及检测单元，被配置为检测物体的基重和厚度中的至少一个 。
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135.发明申请SAMPLE HOLDING CARRIER, AND FLUORESCENCE DETECTION SYSTEM AND FLUORESCENCE DETECTION DEVICE THAT USE SAME 有权样品保持载体和荧光检测系统以及使用相同的荧光检测装置公开(公告)号：US20150048256A1
公开(公告)日：2015-02-19
申请号：US14498877
申请日：2014-09-26
Applicant: PANASONIC CORPORATION , SANYO Electric Co., Ltd.
Inventor： Yoshiyuki MATSUMURA , Kenji NAGATOMI , Masaya NAKATANI , Akio OKI , Morio NAKATANI , Takuya HAYASHI , Masaaki HAYAMA
CPC classification number: G01N21/645 , B01L3/5085 , B01L2300/024 , B01L2300/0654 , B01L2300/0803 , B01L2300/0806 , B01L2300/0819 , B01L2300/0893 , B01L2300/168 , G01N21/03 , G01N21/6447 , G01N21/6452 , G01N35/00069 , G01N2021/6463 , G01N2021/6482 , G01N2201/105 , G11B7/00 , G11B7/09
Abstract: The present invention provides a sample holding carrier that can accurately measure a sample with a simple configuration, and a fluorescence detection system and device that use the same. Biosensor substrate includes: base substrate on which excitation light is incident from a lower surface; reflecting film that is arranged on an upper surface of base substrate to partially reflect the excitation light; and plural wells that are arranged on an upper surface side of reflecting film and have bottom surface portions. The excitation light is converged to be incident on base substrate. Distance from reflecting surface that is of a boundary between reflecting film and base substrate to bottom surface portion of well is less than or equal to a focal depth of the excitation light. Therefore, the sample accommodated in bottom surface portion of well can surely and efficiently be irradiated with the excitation light, and accurately be measured.
Abstract translation: 本发明提供一种能够以简单的结构准确测量样品的样品保持载体和使用其的荧光检测系统和装置。 生物传感器基板包括：激发光从其下表面入射的基底基板; 反射膜，其布置在基底基板的上表面上以部分地反射激发光; 以及布置在反射膜的上表面侧并具有底表面部分的多个阱。 激发光会聚到入射到基底基板上。 与反射膜和基底之间的边界的反射面与孔的底面部的距离小于或等于激发光的焦深。 因此，能够可靠且有效地利用激发光照射容纳在井底部的样品，并且可以精确地测量。
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Patent Agency Ranking
公开(公告)号：US20150042987A1
公开(公告)日：2015-02-12
申请号：US14525673
申请日：2014-10-28
Applicant: KLA-Tencor Corporation
Inventor： Richard E. Bills , Neil Judell , Klaus R. Freischlad , James P. McNiven
CPC classification number: G01N21/9501 , G01N21/21 , G01N21/47 , G01N21/4738 , G01N21/474 , G01N21/55 , G01N21/88 , G01N21/8806 , G01N21/95 , G01N21/956 , G01N2021/4707 , G01N2021/4711 , G01N2021/4792 , G01N2021/556 , G01N2021/8809 , G01N2021/8848 , G01N2021/8864 , G01N2021/8877 , G01N2021/8896 , G01N2201/0612 , G01N2201/105 , G06T7/0004 , G06T2207/30148 , Y10T29/49826
Abstract: A surface inspection system, as well as related components and methods, are provided. The surface inspection system includes a beam source subsystem, a beam scanning subsystem, a workpiece movement subsystem, an optical collection and detection subsystem, and a processing subsystem. The optical collection and detection system features, in the front quartersphere, a light channel assembly for collecting light reflected from the surface of the workpiece, and a front collector and wing collectors for collecting light scattered from the surface, to greatly improve the measurement capabilities of the system. The light channel assembly has a switchable edge exclusion mask and a reflected light detection system for improved detection of the reflected light.
Abstract translation: 提供了表面检查系统，以及相关的部件和方法。 表面检查系统包括光束源子系统，光束扫描子系统，工件运动子系统，光学收集和检测子系统以及处理子系统。 光学收集和检测系统在前四分之一区域中具有用于收集从工件表面反射的光的光通道组件，以及用于收集从表面散射的光的前收集器和翼收集器，以大大提高测量能力 系统。 光通道组件具有可切换的边缘排除掩模和用于改进反射光检测的反射光检测系统。
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公开(公告)号：US08922860B2
公开(公告)日：2014-12-30
申请号：US13613141
申请日：2012-09-13
Applicant: Cameron John Tovey
Inventor： Cameron John Tovey
CPC classification number: G01N21/253 , G01N21/774 , G01N2021/7773 , G01N2021/7793 , G01N2021/7796 , G01N2201/10 , G01N2201/1042 , G01N2201/105
Abstract: Motion control system and method for biosensor scanning that include inputting to a multi-axis motion controller move commands associated with the scan path as defined by multiple axes. The multiple axes including an x-baseline coordinate x0, a y-baseline coordinate y0, an x-direction oscillation amplitude x1, a y-direction oscillation amplitude y1, an oscillation frequency f and a phase φ. The multi-axis motion controller outputs digital commanded positions for each of the multiple axes. A post-processor receives the commanded positions and generates parameterized commanded positions x and y that each include a baseline motion component and an oscillating motion component. The parameterized commanded positions cause the scanning optical system to deflect the light beam to scan the beam spot over the scan path to scan the biosensor.
Abstract translation: 用于生物传感器扫描的运动控制系统和方法包括向多轴运动控制器输入移动与由多个轴定义的扫描路径相关联的命令。 多个轴包括x基线坐标x0，y基线坐标y0，x方向振荡振幅x1，y方向振荡振幅y1，振荡频率f和相位＆phgr。 多轴运动控制器为每个多轴输出数字指令位置。 后处理器接收命令位置并产生每个包括基线运动分量和振荡运动分量的参数化指令位置x和y。 参数化的命令位置使得扫描光学系统偏转光束以扫描扫描路径上的束斑以扫描生物传感器。
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公开(公告)号：US08867817B1
公开(公告)日：2014-10-21
申请号：US13663329
申请日：2012-10-29
Applicant: Amazon Technologies, Inc.
Inventor： Ted John Cooper , Omair Abdul Rahman
CPC classification number: G09G3/006 , G01N21/8851 , G01N21/95 , G01N2201/105 , G06K9/00 , G06K9/68 , G06T7/0004 , G06T7/001 , G06T2207/10008 , G06T2207/10024 , G06T2207/10048 , G06T2207/30121 , G09G5/02 , G09G2330/10
Abstract: A method for analyzing a display is described. The method includes scanning the display to generate a scanned image of the display. The scanned image may be analyzed to determine a characteristic of the display, such as whether or not the display is defective.
Abstract translation: 描述用于分析显示器的方法。 该方法包括扫描显示器以产生显示器的扫描图像。 可以分析扫描图像以确定显示器的特性，例如显示器是否有缺陷。
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公开(公告)号：US20140242717A1
公开(公告)日：2014-08-28
申请号：US13777053
申请日：2013-02-26
Inventor： Daniel Rochette , Pascal Gallant , Ozge Mermut , Francois Baribeau , Isabelle Noiseux , Isabelle Gosselin
IPC: G01N21/94
CPC classification number: G01N21/6428 , A61L2/28 , A61L2202/24 , G01N21/6486 , G01N21/94 , G01N2021/6417 , G01N2021/6439 , G01N2201/06113 , G01N2201/068 , G01N2201/0697 , G01N2201/10 , G01N2201/105
Abstract: A method and apparatus for optical detection of residual soil on articles (such as medical instruments and equipment), after completion of a washing or a rinsing operation by a washer. A soil detection system provides an indication of soil on the articles by detecting luminescent radiation emanating from the soil in the presence of ambient light.
Abstract translation: 在清洗完成洗涤或冲洗操作之后，用于光学检测物品（例如医疗仪器和设备）上残留土壤的方法和装置。 土壤检测系统通过在环境光的存在下检测从土壤发出的发光辐射来提供物品上的土壤的指示。
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140.发明申请OPTICAL ANALYSIS DEVICE, OPTICAL ANALYSIS METHOD AND COMPUTER PROGRAM FOR OPTICAL ANALYSIS USING SINGLE LIGHT-EMITTING PARTICLE DETECTION 有权光学分析装置，光学分析方法和使用单发光颗粒检测的光学分析的计算机程序公开(公告)号：US20140162268A1
公开(公告)日：2014-06-12
申请号：US14178442
申请日：2014-02-12
Applicant: OLYMPUS CORPORATION
Inventor： Tetsuya Tanabe , Mitsushiro Yamaguchi
IPC: G01N21/64
CPC classification number: G01N21/64 , G01N15/14 , G01N15/1429 , G01N15/1434 , G01N21/51 , G01N21/6408 , G01N21/645 , G01N21/6452 , G01N21/6458 , G01N21/6486 , G01N2021/6419 , G01N2021/6441 , G01N2201/103 , G01N2201/105 , G02B21/0032 , G02B21/0076 , G02B21/008
Abstract: In the scanning molecule counting method detecting light of a light-emitting particle in a sample solution using a confocal or multiphoton microscope, there is provided an optical analysis technique enabling the scanning in a sample solution with moving a light detection region in a broader area or along a longer route while making the possibility of detecting the same light-emitting particle as different particles as low as possible and remaining the size or shape of the light detection region unchanged as far as possible. In the inventive optical analysis technique, there are performed detecting light from the light detection region and generating time series light intensity data during moving the light detection region along the second route whose position is moved along the first route, and thereby, the signal indicating light from each light-emitting particle in a predetermined route is individually detected using the time series light intensity data.
Abstract translation: 在使用共聚焦或多光子显微镜检测样品溶液中的发光粒子的光的扫描分子计数方法中，提供了一种光学分析技术，其能够在较宽区域中移动光检测区域的样品溶液中进行扫描，或 沿着较长的路线，同时尽可能地检测与不同粒子相同的发光粒子的可能性，并尽可能地保持光检测区域的尺寸或形状不变。 在本发明的光学分析技术中，在沿着沿第一路线移动位置的第二路径移动光检测区域的同时，进行来自光检测区域的检测光并产生时间序列光强度数据，由此，指示光 使用时间序列光强度数据分别检测来自预定路线中的每个发光粒子。
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